STRINGSTRING
acsA acsA AMR76286.1 AMR76286.1 AMR76332.1 AMR76332.1 AMR76424.1 AMR76424.1 AMR76429.1 AMR76429.1 gpmA gpmA AMR76893.1 AMR76893.1 AMR76904.1 AMR76904.1 AMR76970.1 AMR76970.1 AMR77031.1 AMR77031.1 AMR77033.1 AMR77033.1 AMR77034.1 AMR77034.1 AMR77035.1 AMR77035.1 AMR77037.1 AMR77037.1 ackA ackA AMR80196.1 AMR80196.1 serC serC fbp fbp AMR77411.1 AMR77411.1 eno eno AMR80239.1 AMR80239.1 AMR77505.1 AMR77505.1 ackA-2 ackA-2 AMR78114.1 AMR78114.1 AMR80277.1 AMR80277.1 AMR78245.1 AMR78245.1 AMR78250.1 AMR78250.1 AMR78489.1 AMR78489.1 AMR78745.1 AMR78745.1 mdh mdh glyA glyA ppc ppc AMR79556.1 AMR79556.1 AMR79558.1 AMR79558.1 AMR79559.1 AMR79559.1 AMR79561.1 AMR79561.1 AMR79913.1 AMR79913.1 AMR80596.1 AMR80596.1 AMR80712.1 AMR80712.1 AMR80890.1 AMR80890.1 AMR80896.1 AMR80896.1 AMR80926.1 AMR80926.1 AMR81013.1 AMR81013.1 AMR81090.1 AMR81090.1 AMR81091.1 AMR81091.1 AMR81135.1 AMR81135.1 A2G96_26635 A2G96_26635 AMR81485.1 AMR81485.1 AMR81553.1 AMR81553.1 AMR81609.1 AMR81609.1 AMR81795.1 AMR81795.1 AMR82031.1 AMR82031.1 AMR82047.1 AMR82047.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (660 aa)
AMR76286.1Aldehyde-activating protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (116 aa)
AMR76332.1Hydroxypyruvate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (437 aa)
AMR76424.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (64 aa)
AMR76429.13-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (341 aa)
gpmAPhosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (248 aa)
AMR76893.1Hydroxypyruvate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (435 aa)
AMR76904.1Phosphoglycerate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate mutase family. (224 aa)
AMR76970.1Fructose-1,6-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (354 aa)
AMR77031.14Fe-4S ferredoxin; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. (109 aa)
AMR77033.1Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (185 aa)
AMR77034.1Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (520 aa)
AMR77035.1Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (962 aa)
AMR77037.1Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (74 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (411 aa)
AMR80196.1Catalyzes the formation of acetyl phosphate from acetyl-CoA and phosphate; can also act with other short-chain acyl-CoAs; Derived by automated computational analysis using gene prediction method: Protein Homology. (320 aa)
serC3-phosphoserine/phosphohydroxythreonine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (385 aa)
fbpFructose-bisphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FBPase class 1 family. (338 aa)
AMR77411.1Fructose-2,6-bisphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (242 aa)
enoPhosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (429 aa)
AMR80239.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (284 aa)
AMR77505.1AMP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (576 aa)
ackA-2Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (377 aa)
AMR78114.1Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (284 aa)
AMR80277.1ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (353 aa)
AMR78245.1HAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (360 aa)
AMR78250.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (358 aa)
AMR78489.1Aldehyde-activating protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (131 aa)
AMR78745.1Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (794 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (327 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (415 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (1018 aa)
AMR79556.1Formate dehydrogenase subunit gamma; Derived by automated computational analysis using gene prediction method: Protein Homology. (408 aa)
AMR79558.1Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (233 aa)
AMR79559.1Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (1015 aa)
AMR79561.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (212 aa)
AMR79913.1Molybdopterin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (702 aa)
AMR80596.1Fructose-bisphosphate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (340 aa)
AMR80712.1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (362 aa)
AMR80890.1Derived by automated computational analysis using gene prediction method: Protein Homology. (195 aa)
AMR80896.1D-3-phosphoglycerate dehydrogenase; Catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (408 aa)
AMR80926.1Acetaldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (133 aa)
AMR81013.1Phosphate acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (343 aa)
AMR81090.1NADH-quinone oxidoreductase subunit F; Derived by automated computational analysis using gene prediction method: Protein Homology. (569 aa)
AMR81091.1Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (940 aa)
AMR81135.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (298 aa)
A2G96_26635S-(hydroxymethyl)glutathione dehydrogenase; Serine hydrolase involved in the detoxification of formaldehyde. (280 aa)
AMR81485.1AMP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (553 aa)
AMR81553.1ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (353 aa)
AMR81609.1Serine--glyoxylate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (406 aa)
AMR81795.13-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (311 aa)
AMR82031.1Aldehyde-activating protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (152 aa)
AMR82047.1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (361 aa)
Your Current Organism:
Cupriavidus nantongensis
NCBI taxonomy Id: 1796606
Other names: C. nantongensis, Cupriavidus nantongensis Sun et al. 2016, Cupriavidus sp. X1, KCTC 42909, LMG 29218, LMG:29218, strain X1
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