STRINGSTRING
ANU74789.1 ANU74789.1 ANU74798.1 ANU74798.1 ANU74842.1 ANU74842.1 ANU74867.1 ANU74867.1 leuB leuB ilvD ilvD ANU75027.1 ANU75027.1 ANU75064.1 ANU75064.1 ANU75110.1 ANU75110.1 ackA ackA ANU75316.1 ANU75316.1 ANU75335.1 ANU75335.1 ANU75336.1 ANU75336.1 ANU75404.1 ANU75404.1 ANU78573.2 ANU78573.2 ANU75414.1 ANU75414.1 ANU75679.1 ANU75679.1 ANU75681.1 ANU75681.1 ANU75787.1 ANU75787.1 leuA leuA leuD leuD leuC leuC ilvC ilvC ANU75804.1 ANU75804.1 ANU75898.1 ANU75898.1 ANU75899.1 ANU75899.1 ANU75904.1 ANU75904.1 ANU75905.1 ANU75905.1 ANU76062.1 ANU76062.1 ANU76117.1 ANU76117.1 ANU76118.1 ANU76118.1 ANU76277.1 ANU76277.1 ANU76278.1 ANU76278.1 ANU76279.1 ANU76279.1 ANU76280.2 ANU76280.2 ANU76282.1 ANU76282.1 ANU78648.1 ANU78648.1 ANU76383.1 ANU76383.1 ANU76442.1 ANU76442.1 ANU76484.1 ANU76484.1 ANU76573.1 ANU76573.1 ANU76574.1 ANU76574.1 ANU76575.1 ANU76575.1 ANU76576.1 ANU76576.1 ANU76577.1 ANU76577.1 ANU76578.1 ANU76578.1 ANU76579.1 ANU76579.1 ANU76643.1 ANU76643.1 ANU76644.1 ANU76644.1 ANU76888.2 ANU76888.2 ANU76911.1 ANU76911.1 ANU76995.2 ANU76995.2 ANU76996.1 ANU76996.1 ANU77247.1 ANU77247.1 ANU77248.1 ANU77248.1 ldh ldh ANU77887.1 ANU77887.1 ANU78025.1 ANU78025.1 ANU78080.1 ANU78080.1 ANU78144.1 ANU78144.1 ANU78163.1 ANU78163.1 ANU78311.1 ANU78311.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ANU74789.1Aminotransferase; Broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; Derived by automated computational analysis using gene prediction method: Protein Homology. (406 aa)
ANU74798.1Citrate synthase; Catalyzes the formation of citrate from acetyl-CoA and oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology. (452 aa)
ANU74842.1Pyruvate:ferredoxin (flavodoxin) oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1176 aa)
ANU74867.1Pyruvate, phosphate dikinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the PEP-utilizing enzyme family. (874 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (360 aa)
ilvDDihydroxy-acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (555 aa)
ANU75027.1Acetolactate synthase, large subunit, biosynthetic type; Derived by automated computational analysis using gene prediction method: Protein Homology. (561 aa)
ANU75064.12-hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (332 aa)
ANU75110.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (193 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (400 aa)
ANU75316.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (288 aa)
ANU75335.1glutaconyl-CoA decarboxylase subunit beta; Tunnel subunit of the primary sodium pump glutaconyl-CoA decarboxylase (GCD). (385 aa)
ANU75336.1Converts oxaloacetate to phosphoenolpyruvate using ATP as an energy source; Derived by automated computational analysis using gene prediction method: Protein Homology. (470 aa)
ANU75404.1Propanediol utilization protein; Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate. (207 aa)
ANU78573.2Radical SAM protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (303 aa)
ANU75414.1Glycyl radical enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. (790 aa)
ANU75679.1Isocitrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (403 aa)
ANU75681.12-isopropylmalate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (462 aa)
ANU75787.1Phosphoenolpyruvate carboxykinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (563 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (551 aa)
leuD3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. (162 aa)
leuC3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (422 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (337 aa)
ANU75804.1Acetolactate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (170 aa)
ANU75898.1Pyruvate formate-lyase 1-activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. (255 aa)
ANU75899.1Formate C-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (750 aa)
ANU75904.1Formate C-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (741 aa)
ANU75905.1Pyruvate formate-lyase 1-activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. (255 aa)
ANU76062.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (455 aa)
ANU76117.1Fumarate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (178 aa)
ANU76118.1Fumarate hydratase; Catalyzes the reversible hydration of fumaric acid to yield I-malic acid; Derived by automated computational analysis using gene prediction method: Protein Homology. (281 aa)
ANU76277.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (314 aa)
ANU76278.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (375 aa)
ANU76279.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (81 aa)
ANU76280.2Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (177 aa)
ANU76282.1Branched-chain amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (356 aa)
ANU78648.1NAD-dependent malic enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. (391 aa)
ANU76383.1Zinc-binding alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (371 aa)
ANU76442.1Methylmalonate-semialdehyde dehydrogenase (CoA acylating); Derived by automated computational analysis using gene prediction method: Protein Homology. (507 aa)
ANU76484.1Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family. (478 aa)
ANU76573.1acetyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (706 aa)
ANU76574.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (179 aa)
ANU76575.12-oxoglutarate oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (245 aa)
ANU76576.13-methyl-2-oxobutanoate dehydrogenase subunit VorB; Catalyzes the coenzyme A-dependent oxidation of 3-methyl-2-oxobutanoate coupled to the reduction of ferredoxin producing S-(2-methylpropanoyl)-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (350 aa)
ANU76577.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (67 aa)
ANU76578.1MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (415 aa)
ANU76579.1Amino acid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (390 aa)
ANU76643.1Acetolactate synthase, large subunit, biosynthetic type; Derived by automated computational analysis using gene prediction method: Protein Homology. (574 aa)
ANU76644.1Acetolactate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (165 aa)
ANU76888.2Acylphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (89 aa)
ANU76911.1Branched-chain amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (341 aa)
ANU76995.2Pyruvate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (742 aa)
ANU76996.1Ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (364 aa)
ANU77247.1Hydrolyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (186 aa)
ANU77248.1Fumarate hydratase; Catalyzes the reversible hydration of fumaric acid to yield I-malic acid; Derived by automated computational analysis using gene prediction method: Protein Homology. (280 aa)
ldhL-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (315 aa)
ANU77887.1Dihydroxy-acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (573 aa)
ANU78025.1Propanediol utilization protein; Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate. (189 aa)
ANU78080.1NAD-dependent malic enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. (390 aa)
ANU78144.1Dihydroxy-acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (576 aa)
ANU78163.1Hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (762 aa)
ANU78311.1Bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (872 aa)
Your Current Organism:
Blautia sp. YL58
NCBI taxonomy Id: 1796616
Other names: B. sp. YL58
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