STRINGSTRING
SJZ95697.1 SJZ95697.1 SJZ95565.1 SJZ95565.1 SJZ95367.1 SJZ95367.1 rnmV rnmV SJZ94780.1 SJZ94780.1 SJZ94617.1 SJZ94617.1 SJZ94493.1 SJZ94493.1 SJZ94323.1 SJZ94323.1 SJZ94210.1 SJZ94210.1 SJZ94126.1 SJZ94126.1 leuS leuS SJZ93216.1 SJZ93216.1 SJZ93198.1 SJZ93198.1 tsaD tsaD truA truA SJZ92537.1 SJZ92537.1 pheT pheT pheS pheS gyrA gyrA gyrB gyrB recF recF rnpA rnpA mnmE mnmE mnmG-2 mnmG-2 mfd mfd SJZ90842.1 SJZ90842.1 SJZ90719.1 SJZ90719.1 SJZ90231.1 SJZ90231.1 SJZ89539.1 SJZ89539.1 SJZ89186.1 SJZ89186.1 SJZ86635.1 SJZ86635.1 sbcD sbcD mutS2 mutS2 cysS cysS mrnC mrnC SJZ84577.1 SJZ84577.1 ruvB ruvB SJZ84296.1 SJZ84296.1 SJZ84269.1 SJZ84269.1 rnj rnj SJZ84156.1 SJZ84156.1 SJZ84086.1 SJZ84086.1 rsmI rsmI dnaJ dnaJ rnr rnr tdk tdk SJZ83008.1 SJZ83008.1 ung ung trpS trpS SJZ82554.1 SJZ82554.1 SJZ81482.1 SJZ81482.1 SJZ81439.1 SJZ81439.1 SJZ81423.1 SJZ81423.1 SJZ81334.1 SJZ81334.1 SJZ81056.1 SJZ81056.1 SJZ80889.1 SJZ80889.1 SJZ80429.1 SJZ80429.1 SJZ79358.1 SJZ79358.1 rlmN rlmN SJZ77504.1 SJZ77504.1 SJZ75108.1 SJZ75108.1 SJZ74890.1 SJZ74890.1 SJZ74868.1 SJZ74868.1 SJZ69304.1 SJZ69304.1 nfo nfo SJZ67136.1 SJZ67136.1 SJZ67107.1 SJZ67107.1 queH queH SJZ66551.1 SJZ66551.1 cas2-2 cas2-2 cas1-2 cas1-2 SJZ63949.1 SJZ63949.1 SJZ63634.1 SJZ63634.1 asnS asnS SJZ58547.1 SJZ58547.1 SJZ58494.1 SJZ58494.1 SJZ55672.1 SJZ55672.1 SJZ54722.1 SJZ54722.1 recA recA SJZ52869.1 SJZ52869.1 SJZ48744.1 SJZ48744.1 SJZ48712.1 SJZ48712.1 SJZ48621.1 SJZ48621.1 nusB nusB SJZ48420.1 SJZ48420.1 rnhB rnhB SJZ48374.1 SJZ48374.1 rnc rnc SJZ47983.1 SJZ47983.1 SJZ47979.1 SJZ47979.1 radA radA SJZ47942.1 SJZ47942.1 SJZ47761.1 SJZ47761.1 miaB miaB rho rho SJZ47633.1 SJZ47633.1 queA queA SJZ47518.1 SJZ47518.1 xseB xseB SJZ47314.1 SJZ47314.1 tmcAL tmcAL SJZ46941.1 SJZ46941.1 SJZ46838.1 SJZ46838.1 SJZ46819.1 SJZ46819.1 thrS thrS SJZ46715.1 SJZ46715.1 mutS mutS alaS alaS SJZ46600.1 SJZ46600.1 SJZ46344.1 SJZ46344.1 recR recR uvrA uvrA ruvA ruvA SJZ45699.1 SJZ45699.1 hisS hisS aspS aspS argS argS uvrC uvrC SJZ45295.1 SJZ45295.1 SJZ45282.1 SJZ45282.1 SJZ45168.1 SJZ45168.1 SJZ44973.1 SJZ44973.1 uvrB uvrB xseA xseA topA topA trmFO trmFO SJZ44774.1 SJZ44774.1 priA priA SJZ44228.1 SJZ44228.1 ybeY ybeY ruvC ruvC SJZ43918.1 SJZ43918.1 SJZ43830.1 SJZ43830.1 SJZ43659.1 SJZ43659.1 mutL mutL rlmH rlmH lysS lysS SJZ43155.1 SJZ43155.1 gatC gatC gatB gatB truB truB rsmA rsmA rimM rimM trmD trmD SJZ42709.1 SJZ42709.1 polC polC SJZ41154.1 SJZ41154.1 selA selA SJZ38377.1 SJZ38377.1 SJZ38142.1 SJZ38142.1 polA polA SJZ38014.1 SJZ38014.1 SJZ37881.1 SJZ37881.1 SJZ37839.1 SJZ37839.1 SJZ37816.1 SJZ37816.1 SJZ37741.1 SJZ37741.1 SJZ37711.1 SJZ37711.1 mnmA mnmA SJZ37504.1 SJZ37504.1 cas2 cas2 cas1 cas1 SJZ37455.1 SJZ37455.1 SJZ37411.1 SJZ37411.1 SJZ36899.1 SJZ36899.1 SJZ36824.1 SJZ36824.1 SJZ36514.1 SJZ36514.1 dtd dtd SJZ36052.1 SJZ36052.1 SJZ35839.1 SJZ35839.1 dnaX dnaX SJZ35677.1 SJZ35677.1 SJZ35659.1 SJZ35659.1 SJZ35596.1 SJZ35596.1 rsmH rsmH rimO rimO pnp pnp tgt tgt fmt fmt recO recO serS serS rsmG rsmG mnmG mnmG psuG psuG SJZ34782.1 SJZ34782.1 tilS tilS SJZ34488.1 SJZ34488.1 SJZ34480.1 SJZ34480.1 smc smc rph rph SJZ34144.1 SJZ34144.1 SJZ34024.1 SJZ34024.1 SJZ34006.1 SJZ34006.1 SJZ33948.1 SJZ33948.1 metG metG valS valS SJZ33588.1 SJZ33588.1 rbfA rbfA nusA nusA glyS glyS glyQ glyQ ileS ileS trmB trmB SJZ33137.1 SJZ33137.1 rny rny miaA miaA SJZ32897.1 SJZ32897.1 proS proS recG recG SJZ32725.1 SJZ32725.1 SJZ32663.1 SJZ32663.1 SJZ32602.1 SJZ32602.1 SJZ95793.1 SJZ95793.1 SJZ95927.1 SJZ95927.1 SJZ95945.1 SJZ95945.1 SJZ95987.1 SJZ95987.1 mnmA-2 mnmA-2 ligA ligA SJZ97268.1 SJZ97268.1 SJZ97453.1 SJZ97453.1 gltX gltX rpsK rpsK rpoA rpoA dnaG dnaG sigA sigA SJZ98989.1 SJZ98989.1 SJZ99329.1 SJZ99329.1 nth nth SKA00325.1 SKA00325.1 tyrS tyrS rpoZ rpoZ SKA00557.1 SKA00557.1 rpoC rpoC rpoB rpoB rplA rplA nusG nusG SKA01136.1 SKA01136.1 SKA01267.1 SKA01267.1 SKA01306.1 SKA01306.1 SKA01474.1 SKA01474.1 SKA02277.1 SKA02277.1 SKA02422.1 SKA02422.1 SKA02445.1 SKA02445.1 dinB dinB SKA04663.1 SKA04663.1 SKA04697.1 SKA04697.1 SKA04741.1 SKA04741.1 SKA04778.1 SKA04778.1 SKA04796.1 SKA04796.1 SKA04842.1 SKA04842.1 SKA04862.1 SKA04862.1 SKA05086.1 SKA05086.1 SKA05281.1 SKA05281.1 SKA05301.1 SKA05301.1 SKA05314.1 SKA05314.1 SKA05328.1 SKA05328.1 SKA05558.1 SKA05558.1 SKA06203.1 SKA06203.1 SKA06547.1 SKA06547.1 SKA06969.1 SKA06969.1 SKA06982.1 SKA06982.1 SKA07470.1 SKA07470.1 SKA08730.1 SKA08730.1 SKA09430.1 SKA09430.1 SKA09779.1 SKA09779.1 SKA09792.1 SKA09792.1 SKA09986.1 SKA09986.1 SKA10333.1 SKA10333.1 SKA10876.1 SKA10876.1 SKA10977.1 SKA10977.1 SKA11353.1 SKA11353.1 SKA11622.1 SKA11622.1 SKA11803.1 SKA11803.1 SKA12006.1 SKA12006.1 SKA12203.1 SKA12203.1 SKA12464.1 SKA12464.1 SKA12474.1 SKA12474.1 SKA12826.1 SKA12826.1 SKA12929.1 SKA12929.1 SKA13802.1 SKA13802.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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SJZ95697.1Replication initiator protein A (RepA) N-terminus. (366 aa)
SJZ95565.1BRCA1 C Terminus (BRCT) domain-containing protein. (330 aa)
SJZ95367.1Phage terminase, large subunit GpA. (606 aa)
rnmVRibonuclease M5; Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step. (184 aa)
SJZ94780.1Hypothetical protein. (235 aa)
SJZ94617.1Putative transposase. (371 aa)
SJZ94493.1DNA-binding protein HU-beta; Belongs to the bacterial histone-like protein family. (91 aa)
SJZ94323.1Exodeoxyribonuclease-3. (251 aa)
SJZ94210.1DNA polymerase-3 subunit beta. (363 aa)
SJZ94126.1RNA methyltransferase, TrmH family. (255 aa)
leuSleucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (869 aa)
SJZ93216.1RNA polymerase, sigma 30 subunit, SigH; Belongs to the sigma-70 factor family. (200 aa)
SJZ93198.123S rRNA (guanosine2251-2'-O)-methyltransferase; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (237 aa)
tsaDN6-L-threonylcarbamoyladenine synthase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (337 aa)
truAtRNA pseudouridine38-40 synthase; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (243 aa)
SJZ92537.123S rRNA pseudouridine1911/1915/1917 synthase. (290 aa)
pheTphenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (797 aa)
pheSphenylalanyl-tRNA synthetase, alpha subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (338 aa)
gyrADNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (820 aa)
gyrBDNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (634 aa)
recFDNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. (365 aa)
rnpARibonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. (113 aa)
mnmEtRNA modification GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. (455 aa)
mnmG-2tRNA uridine 5-carboxymethylaminomethyl modification enzyme; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. (616 aa)
mfdTranscription-repair coupling factor (superfamily II helicase); Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (914 aa)
SJZ90842.116S rRNA pseudouridine516 synthase; Belongs to the pseudouridine synthase RsuA family. (230 aa)
SJZ90719.1tRNA G10 N-methylase Trm11. (310 aa)
SJZ90231.1Endonuclease YncB, thermonuclease family. (158 aa)
SJZ89539.1RNA polymerase nonessential primary-like sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (275 aa)
SJZ89186.1Autotransporter beta-domain-containing protein. (1023 aa)
SJZ86635.1DNA polymerase-3 subunit epsilon. (184 aa)
sbcDExodeoxyribonuclease I subunit D; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. (387 aa)
mutS2DNA mismatch repair protein MutS2; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. (779 aa)
cysScysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (473 aa)
mrnCRibonuclease-3 family protein; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors; Belongs to the MrnC RNase family. (126 aa)
SJZ84577.1DNA polymerase-3 subunit delta'. (305 aa)
ruvBHolliday junction DNA helicase subunit RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (329 aa)
SJZ84296.116S rRNA (uracil1498-N3)-methyltransferase; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. (237 aa)
SJZ84269.1Threonylcarbamoyladenosine tRNA methylthiotransferase MtaB. (434 aa)
rnjRibonuclease J; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay. (656 aa)
SJZ84156.1RNA-binding protein. (102 aa)
SJZ84086.13'-5' exoribonuclease YhaM, can participate in 23S rRNA maturation, HD superfamily. (278 aa)
rsmI16S rRNA (cytidine1402-2'-O)-methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. (221 aa)
dnaJMolecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] (383 aa)
rnrRibonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. (709 aa)
tdkThymidine kinase. (200 aa)
SJZ83008.1tRNA pseudouridine(38-40) synthase. (284 aa)
ungUracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (225 aa)
trpStryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (327 aa)
SJZ82554.1DnaJ domain-containing protein. (181 aa)
SJZ81482.1CRISPR-associated endoribonuclease Cas6. (262 aa)
SJZ81439.1CRISPR/Cas system CSM-associated protein Csm3, group 7 of RAMP superfamily. (277 aa)
SJZ81423.1CRISPR-associated protein, Csx7 family. (250 aa)
SJZ81334.1Hypothetical protein. (550 aa)
SJZ81056.123S rRNA m(6)A-1618 methyltransferase; Specifically methylates the adenine in position 1618 of 23S rRNA. (294 aa)
SJZ80889.1RNA polymerase, sigma 30 subunit, SigH; Belongs to the sigma-70 factor family. (196 aa)
SJZ80429.1Hypothetical protein. (568 aa)
SJZ79358.1alanyl-tRNA synthetase. (373 aa)
rlmN23S rRNA (adenine2503-C2)-methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. (350 aa)
SJZ77504.1Initiator Replication protein. (379 aa)
SJZ75108.1Phage integrase family protein. (197 aa)
SJZ74890.1AAA domain (dynein-related subfamily). (480 aa)
SJZ74868.15-methylcytosine-specific restriction enzyme subunit McrC. (407 aa)
SJZ69304.1Site-specific DNA recombinase. (252 aa)
nfoEndonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. (284 aa)
SJZ67136.116S rRNA pseudouridine516 synthase; Belongs to the pseudouridine synthase RsuA family. (226 aa)
SJZ67107.1Integrase/recombinase XerD; Belongs to the 'phage' integrase family. (330 aa)
queHHypothetical protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr). (212 aa)
SJZ66551.1DNA-binding protein HU-beta; Belongs to the bacterial histone-like protein family. (90 aa)
cas2-2CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (93 aa)
cas1-2CRISP-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (330 aa)
SJZ63949.1CRISPR-associated exonuclease Cas4. (136 aa)
SJZ63634.1Sulfur carrier protein ThiS adenylyltransferase. (178 aa)
asnSasparaginyl-tRNA synthetase. (463 aa)
SJZ58547.1Hypothetical protein. (370 aa)
SJZ58494.1Hypothetical protein. (217 aa)
SJZ55672.123S rRNA pseudouridine1911/1915/1917 synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (295 aa)
SJZ54722.1DNA-binding protein HU-beta; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. (92 aa)
recARecombination protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (356 aa)
SJZ52869.1Initiator Replication protein. (281 aa)
SJZ48744.1DNA repair protein RecN (Recombination protein N); May be involved in recombinational repair of damaged DNA. (553 aa)
SJZ48712.1Integrase/recombinase XerD; Belongs to the 'phage' integrase family. (269 aa)
SJZ48621.1DNA polymerase-3 subunit alpha. (1138 aa)
nusBNusB antitermination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (134 aa)
SJZ48420.123S rRNA pseudouridine1911/1915/1917 synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (319 aa)
rnhBRNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (201 aa)
SJZ48374.1Putative endonuclease; Belongs to the UPF0102 family. (120 aa)
rncRNAse III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (236 aa)
SJZ47983.1Hypothetical protein. (340 aa)
SJZ47979.1RNAse G. (488 aa)
radADNA repair protein RadA/Sms; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (458 aa)
SJZ47942.1Diadenylate cyclase; Belongs to the DisA family. (351 aa)
SJZ47761.1N-glycosylase/DNA lyase. (217 aa)
miaBtRNA-2-methylthio-N6-dimethylallyladenosine synthase; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. (437 aa)
rhoTranscription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (417 aa)
SJZ47633.1RNA polymerase sigma-70 factor, ECF subfamily. (150 aa)
queAS-adenosylmethionine--tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (343 aa)
SJZ47518.116S rRNA (guanine(966)-N(2))-methyltransferase RsmD. (182 aa)
xseBExodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (76 aa)
SJZ47314.1HD domain-containing protein. (192 aa)
tmcALPredicted nucleotidyltransferase; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac- AMP) and then transfers the acetyl group to tRNA to form ac(4)C34. (384 aa)
SJZ46941.1Ribonuclease HI. (206 aa)
SJZ46838.1tRNA threonylcarbamoyladenosine biosynthesis protein TsaE. (154 aa)
SJZ46819.1N6-L-threonylcarbamoyladenine synthase. (225 aa)
thrSthreonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). (636 aa)
SJZ46715.1Putative TIM-barrel protein, nifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (310 aa)
mutSDNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. (879 aa)
alaSalanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (869 aa)
SJZ46600.1Putative holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. (140 aa)
SJZ46344.123S rRNA pseudouridine955/2504/2580 synthase; Belongs to the pseudouridine synthase RluA family. (306 aa)
recRDNA replication and repair protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (197 aa)
uvrAExcinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (945 aa)
ruvAHolliday junction DNA helicase subunit RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (199 aa)
SJZ45699.1Putative ATPase. (409 aa)
hisShistidyl-tRNA synthetase. (413 aa)
aspSaspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (594 aa)
argSarginyl-tRNA synthetase. (570 aa)
uvrCExcinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. (588 aa)
SJZ45295.1tRNA 2-selenouridine synthase. (345 aa)
SJZ45282.1ATP-dependent DNA helicase RecQ. (631 aa)
SJZ45168.1Putative transposase. (366 aa)
SJZ44973.1Methyltransferase small domain-containing protein; Belongs to the methyltransferase superfamily. (224 aa)
uvrBExcinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (658 aa)
xseAExodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (402 aa)
topADNA topoisomerase-1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (750 aa)
trmFOmethylenetetrahydrofolate--tRNA-(uracil-5-)- methyltransferase; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily. (436 aa)
SJZ44774.1Integrase/recombinase XerD; Belongs to the 'phage' integrase family. (298 aa)
priAReplication restart DNA helicase PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (759 aa)
SJZ44228.1DNA polymerase III, delta subunit. (331 aa)
ybeYProbable rRNA maturation factor; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (157 aa)
ruvCHolliday junction endonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. (192 aa)
SJZ43918.1RNA polymerase primary sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (262 aa)
SJZ43830.1tRNA (cytidine/uridine-2'-O-)-methyltransferase; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily. (154 aa)
SJZ43659.1Exonuclease RecJ. (852 aa)
mutLDNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (582 aa)
rlmH23S rRNA (pseudouridine1915-N3)-methyltransferase; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. (155 aa)
lysSlysyl-tRNA synthetase, class II; Belongs to the class-II aminoacyl-tRNA synthetase family. (492 aa)
SJZ43155.1Ribosomal large subunit pseudouridine synthase B; Belongs to the pseudouridine synthase RsuA family. (236 aa)
gatCaspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. (96 aa)
gatBaspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (481 aa)
truBtRNA pseudouridine55 synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. (285 aa)
rsmA16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (266 aa)
rimM16S rRNA processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. (170 aa)
trmDtRNA (guanine37-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. (241 aa)
SJZ42709.1Hypothetical protein. (187 aa)
polCDNA polymerase-3 subunit alpha; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (1447 aa)
SJZ41154.1Selenium metabolism protein YedF; Belongs to the sulfur carrier protein TusA family. (192 aa)
selAL-seryl-tRNA(Sec) selenium transferase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis. (455 aa)
SJZ38377.1methylated-DNA-[protein]-cysteine S-methyltransferase. (160 aa)
SJZ38142.1Adenine-specific DNA-methyltransferase. (510 aa)
polADNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (885 aa)
SJZ38014.1Single-strand DNA-binding protein. (141 aa)
SJZ37881.1ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains). (1030 aa)
SJZ37839.1PD-(D/E)XK nuclease superfamily protein. (849 aa)
SJZ37816.1Hypothetical protein. (253 aa)
SJZ37741.1Resolvase, N terminal domain. (195 aa)
SJZ37711.1Initiator Replication protein. (307 aa)
mnmAtRNA-specific 2-thiouridylase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (344 aa)
SJZ37504.1CRISPR-associated exonuclease Cas4; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family. (190 aa)
cas2CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (95 aa)
cas1CRISPR-associated protein, Cas1 family; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (319 aa)
SJZ37455.1Group II intron reverse transcriptase/maturase. (295 aa)
SJZ37411.1NYN domain-containing protein. (164 aa)
SJZ36899.1Pseudouridine-5'-phosphate glycosidase. (268 aa)
SJZ36824.1Group II intron reverse transcriptase/maturase. (600 aa)
SJZ36514.1Phosphoesterase RecJ domain-containing protein. (314 aa)
dtdD-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (150 aa)
SJZ36052.1Putative N6-adenine-specific DNA methylase. (379 aa)
SJZ35839.1Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (446 aa)
dnaXDNA polymerase-3 subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (485 aa)
SJZ35677.1DNA polymerase-3 subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] (374 aa)
SJZ35659.1RNA polymerase primary sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (273 aa)
SJZ35596.123S rRNA (uracil1939-C5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (452 aa)
rsmH16S rRNA (cytosine1402-N4)-methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (312 aa)
rimORibosomal protein S12 methylthiotransferase; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. (445 aa)
pnpPolyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (711 aa)
tgtQueuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (388 aa)
fmtmethionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (310 aa)
recODNA replication and repair protein RecO; Involved in DNA repair and RecF pathway recombination. (231 aa)
serSseryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (423 aa)
rsmG16S rRNA m(7)G-527 methyltransferase; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. (233 aa)
mnmGtRNA uridine 5-carboxymethylaminomethyl modification enzyme; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. (629 aa)
psuGPseudouridine-5'-phosphate glycosidase; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family. (305 aa)
SJZ34782.1RNA polymerase sporulation-specific sigma factor; Belongs to the sigma-70 factor family. (201 aa)
tilStRNA(Ile)-lysidine synthase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (448 aa)
SJZ34488.1caffeoyl-CoA O-methyltransferase. (210 aa)
SJZ34480.116S rRNA (cytosine967-C5)-methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. (435 aa)
smcCondensin subunit Smc; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1170 aa)
rphRibonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (246 aa)
SJZ34144.1DNA helicase-2 / ATP-dependent DNA helicase PcrA. (717 aa)
SJZ34024.1tRNA(Ile)-lysidine synthase TilS/MesJ; Belongs to the TtcA family. (268 aa)
SJZ34006.1tRNA(Ile)-lysidine synthase TilS/MesJ; Belongs to the TtcA family. (313 aa)
SJZ33948.1tRNA-specific 2-thiouridylase. (332 aa)
metGmethionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (641 aa)
valSvalyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (886 aa)
SJZ33588.1single-stranded-DNA-specific exonuclease. (572 aa)
rbfARibosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. (118 aa)
nusANusA antitermination factor; Participates in both transcription termination and antitermination. (362 aa)
glySglycyl-tRNA synthetase beta chain. (690 aa)
glyQglycyl-tRNA synthetase alpha chain. (289 aa)
ileSIsoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (931 aa)
trmBtRNA (guanine-N7-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (232 aa)
SJZ33137.13-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (410 aa)
rnyRibonucrease Y; Endoribonuclease that initiates mRNA decay. Belongs to the RNase Y family. (521 aa)
miaAtRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (298 aa)
SJZ32897.1tRNA A37 threonylcarbamoyladenosine dehydratase. (241 aa)
proSprolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] (569 aa)
recGATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (684 aa)
SJZ32725.1DNA polymerase. (190 aa)
SJZ32663.1SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase). (221 aa)
SJZ32602.1DNA helicase-2 / ATP-dependent DNA helicase PcrA; Belongs to the helicase family. UvrD subfamily. (935 aa)
SJZ95793.1AP2-like DNA-binding integrase domain-containing protein; Belongs to the 'phage' integrase family. (354 aa)
SJZ95927.1Transposase, Mutator family; Required for the transposition of the insertion element. (123 aa)
SJZ95945.1Transposase, Mutator family; Required for the transposition of the insertion element. (84 aa)
SJZ95987.1Transposase, IS605 OrfB family, central region. (124 aa)
mnmA-2tRNA-specific 2-thiouridylase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (345 aa)
ligADNA ligase (NAD+); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. (669 aa)
SJZ97268.1Hypothetical protein. (276 aa)
SJZ97453.1TatD DNase family protein. (254 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (503 aa)
rpsKSmall subunit ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (129 aa)
rpoADNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (325 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (599 aa)
sigARNA polymerase primary sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (402 aa)
SJZ98989.1RNA polymerase sigma factor, sigma-70 family. (283 aa)
SJZ99329.1Protein involved in initiation of plasmid replication. (338 aa)
nthDNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (215 aa)
SKA00325.1Hypothetical protein. (151 aa)
tyrStyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (408 aa)
rpoZDNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (69 aa)
SKA00557.1TIGR00255 family protein. (292 aa)
rpoCDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1314 aa)
rpoBDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1166 aa)
rplALarge subunit ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. (234 aa)
nusGTranscription antitermination protein nusG; Participates in transcription elongation, termination and antitermination. (199 aa)
SKA01136.1Protein involved in initiation of plasmid replication. (336 aa)
SKA01267.1Site-specific DNA-methyltransferase (adenine-specific)/modification methylase. (156 aa)
SKA01306.1DNA methylase. (76 aa)
SKA01474.1Phage terminase, large subunit GpA. (614 aa)
SKA02277.1Sigma-70, region 4. (605 aa)
SKA02422.1Ribonucleoside-diphosphate reductase beta chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (344 aa)
SKA02445.1Ribonucleoside-diphosphate reductase class Ia alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (723 aa)
dinBDNA polymerase-4; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (351 aa)
SKA04663.1Hypothetical protein. (281 aa)
SKA04697.1Adenine-specific DNA-methyltransferase. (665 aa)
SKA04741.1LlaJI restriction endonuclease. (435 aa)
SKA04778.1DNA (cytosine-5)-methyltransferase 1. (509 aa)
SKA04796.1DNA (cytosine-5)-methyltransferase 1. (329 aa)
SKA04842.1AAA domain (dynein-related subfamily). (263 aa)
SKA04862.15-methylcytosine-specific restriction enzyme subunit McrC. (345 aa)
SKA05086.1Transposase DDE domain-containing protein. (210 aa)
SKA05281.1AAA domain-containing protein, putative AbiEii toxin, Type IV TA system. (626 aa)
SKA05301.1Type I restriction enzyme, S subunit. (560 aa)
SKA05314.1Type I restriction enzyme M protein. (487 aa)
SKA05328.1Type I restriction enzyme, R subunit. (788 aa)
SKA05558.1Site-specific DNA recombinase. (202 aa)
SKA06203.1Type IV secretion system protein VirB3. (87 aa)
SKA06547.1Initiator Replication protein. (338 aa)
SKA06969.1Transposase, IS605 OrfB family, central region. (124 aa)
SKA06982.1Initiator Replication protein. (390 aa)
SKA07470.1RNA polymerase, sigma 30 subunit, SigH; Belongs to the sigma-70 factor family. (199 aa)
SKA08730.1Rad52/22 family double-strand break repair protein. (266 aa)
SKA09430.1Putative transposase. (277 aa)
SKA09779.1Ribonucleoside-triphosphate reductase class III catalytic subunit. (729 aa)
SKA09792.1Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. (159 aa)
SKA09986.1Short C-terminal domain-containing protein. (177 aa)
SKA10333.1Initiator Replication protein. (370 aa)
SKA10876.1Protein involved in initiation of plasmid replication. (300 aa)
SKA10977.1Hypothetical protein. (132 aa)
SKA11353.1Site-specific DNA recombinase. (189 aa)
SKA11622.1RNA polymerase sporulation-specific sigma factor; Belongs to the sigma-70 factor family. (195 aa)
SKA11803.1Resolvase, N terminal domain. (189 aa)
SKA12006.1Hypothetical protein. (107 aa)
SKA12203.1MobA/MobL family protein. (777 aa)
SKA12464.1Rad52/22 family double-strand break repair protein. (266 aa)
SKA12474.1Helix-turn-helix domain-containing protein. (164 aa)
SKA12826.1Initiator Replication protein. (385 aa)
SKA12929.1Hypothetical protein; Belongs to the 'phage' integrase family. (287 aa)
SKA13802.1Hypothetical protein. (133 aa)
Your Current Organism:
Cetobacterium ceti
NCBI taxonomy Id: 180163
Other names: ATCC 700028, C. ceti, NCFB 3026, NCIMB 703026, strain M-3333
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