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OHC10640.1 OHC10640.1 smc smc OHC10969.1 OHC10969.1 hscA hscA uvrB uvrB clpB clpB OHC10437.1 OHC10437.1 OHC10552.1 OHC10552.1 OHC10592.1 OHC10592.1 OHC10618.1 OHC10618.1 uvrA uvrA OHC09511.1 OHC09511.1 OHC09513.1 OHC09513.1 OHC09130.1 OHC09130.1 ychF ychF OHC09453.1 OHC09453.1 OHC09405.1 OHC09405.1 OHC08946.1 OHC08946.1 OHC09637.1 OHC09637.1 mfd mfd clpX clpX lon lon OHC09982.1 OHC09982.1 ftsH ftsH recG recG htpG htpG ruvA ruvA ruvB ruvB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
OHC10640.1ATP-dependent Clp protease ATP-binding subunit ClpA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ClpA/ClpB family. (768 aa)
smcChromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1173 aa)
OHC10969.1Cobaltochelatase subunit CobS; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa)
hscAFe-S protein assembly chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. (621 aa)
uvrBExcinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (692 aa)
clpBATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. (864 aa)
OHC10437.1Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (831 aa)
OHC10552.1Copper-translocating P-type ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (812 aa)
OHC10592.1AAA family ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (551 aa)
OHC10618.1DNA helicase II; Derived by automated computational analysis using gene prediction method: Protein Homology. (795 aa)
uvrAExcinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (962 aa)
OHC09511.1Copper-transporting ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (765 aa)
OHC09513.1ATP-binding protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (362 aa)
OHC09130.1Type II secretion system protein E; Derived by automated computational analysis using gene prediction method: Protein Homology. (356 aa)
ychFRedox-regulated ATPase YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (364 aa)
OHC09453.1Cell division protein ZapE; Derived by automated computational analysis using gene prediction method: Protein Homology. (367 aa)
OHC09405.1Recombination factor protein RarA; Derived by automated computational analysis using gene prediction method: Protein Homology. (437 aa)
OHC08946.1Cadmium-translocating P-type ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (705 aa)
OHC09637.1AAA family ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (285 aa)
mfdTranscription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1184 aa)
clpXATP-dependent protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (453 aa)
lonEndopeptidase La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (810 aa)
OHC09982.1TIGR02391 family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (558 aa)
ftsHCell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (625 aa)
recGATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (695 aa)
htpGMolecular chaperone HtpG; Molecular chaperone. Has ATPase activity. (633 aa)
ruvAHolliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (194 aa)
ruvBHolliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (356 aa)
Your Current Organism:
Polynucleobacter sp. GWA24521
NCBI taxonomy Id: 1801989
Other names: P. sp. GWA2_45_21, Polynucleobacter sp. GWA2_45_21
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