(15 nodes) Isoprene biosynthesis, and Riboflavin metabolic process network (Sphingorhabdus sp. M41)

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	dxs	1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (642 aa)
	ispG	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (375 aa)
	dxr	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (386 aa)
	folE	GTP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (199 aa)
	ispE	Hypothetical protein; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (284 aa)
	ispDF	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF). (390 aa)
	AMO73336.1	Dihydropteroate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (374 aa)
	AMO72086.1	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (176 aa)
	ispH	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (319 aa)
	ribA	GTP cyclohydrolase; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. (365 aa)
	AMO72678.1	Dihydroneopterin aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (123 aa)
	ribB	3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. (438 aa)
	ribH	6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (140 aa)
	AMO73044.1	Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (202 aa)
	AMO73045.1	Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (326 aa)

Your Current Organism:

Sphingorhabdus sp. M41

NCBI taxonomy Id: 1806885
Other names: S. sp. M41

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMO72086.1	AMO72678.1	AZE99_09725	AZE99_13175	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Dihydroneopterin aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.996
AMO72086.1	AMO73045.1	AZE99_09725	AZE99_15370	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.	0.695
AMO72086.1	AMO73336.1	AZE99_09725	AZE99_08765	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Dihydropteroate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
AMO72086.1	folE	AZE99_09725	AZE99_07135	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	GTP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.985
AMO72086.1	ispDF	AZE99_09725	AZE99_08125	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).	0.637
AMO72086.1	ribB	AZE99_09725	AZE99_14430	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.	0.545
AMO72678.1	AMO72086.1	AZE99_13175	AZE99_09725	Dihydroneopterin aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.996
AMO72678.1	AMO73045.1	AZE99_13175	AZE99_15370	Dihydroneopterin aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.	0.666
AMO72678.1	AMO73336.1	AZE99_13175	AZE99_08765	Dihydroneopterin aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Dihydropteroate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.996
AMO72678.1	folE	AZE99_13175	AZE99_07135	Dihydroneopterin aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	GTP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.965
AMO72678.1	ispDF	AZE99_13175	AZE99_08125	Dihydroneopterin aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).	0.653
AMO72678.1	ribB	AZE99_13175	AZE99_14430	Dihydroneopterin aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.	0.463
AMO73044.1	AMO73045.1	AZE99_15365	AZE99_15370	Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.	0.999
AMO73044.1	ispDF	AZE99_15365	AZE99_08125	Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).	0.450
AMO73044.1	ribA	AZE99_15365	AZE99_11405	Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	GTP cyclohydrolase; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.	0.989
AMO73044.1	ribB	AZE99_15365	AZE99_14430	Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.	0.999
AMO73044.1	ribH	AZE99_15365	AZE99_14435	Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.	0.999
AMO73045.1	AMO72086.1	AZE99_15370	AZE99_09725	Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.695
AMO73045.1	AMO72678.1	AZE99_15370	AZE99_13175	Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.	Dihydroneopterin aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.666
AMO73045.1	AMO73044.1	AZE99_15370	AZE99_15365	Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.	Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999