(140 nodes) Microtubule cytoskeleton network (Aspergillus mulundensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DSM5745_02663	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (389 aa)
	DSM5745_02997	Uncharacterized protein. (398 aa)
	DSM5745_02944	Spindle pole body component. (996 aa)
	DSM5745_02866	Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (548 aa)
	DSM5745_03115	Uncharacterized protein. (267 aa)
	DSM5745_03142	Tyrosine-protein phosphatase cdcA. (596 aa)
	DSM5745_03389	C-CAP/cofactor C-like domain-containing protein. (407 aa)
	DSM5745_03388	Uncharacterized protein. (1011 aa)
	DSM5745_03439	Uncharacterized protein. (475 aa)
	DSM5745_03425	Uncharacterized protein. (1216 aa)
	DSM5745_03489	Kinesin class 6 (MKLP1 group); Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (804 aa)
	DSM5745_03458	Conidiophore development protein hymA. (365 aa)
	DSM5745_03512	Uncharacterized protein. (823 aa)
	DSM5745_03513	Uncharacterized protein; Belongs to the actin family. (555 aa)
	DSM5745_03170	EB1 C-terminal domain-containing protein. (201 aa)
	DSM5745_03768	Kinesin-like protein bimC; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1184 aa)
	DSM5745_03819	Uncharacterized protein. (1599 aa)
	DSM5745_01617	TCTP domain-containing protein; Belongs to the TCTP family. (178 aa)
	DSM5745_01632	Uncharacterized protein. (295 aa)
	DSM5745_01651	Tubulin gamma chain; Belongs to the tubulin family. (791 aa)
	DSM5745_01714	Uncharacterized protein. (894 aa)
	DSM5745_01686	Sfi1 domain-containing protein. (1082 aa)
	DSM5745_01942	J domain-containing protein. (832 aa)
	DSM5745_01866	Uncharacterized protein. (51 aa)
	DSM5745_02010	Uncharacterized protein. (623 aa)
	DSM5745_02054	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (708 aa)
	DSM5745_02074	CAP-Gly domain-containing protein. (1338 aa)
	DSM5745_01976	KapC. (874 aa)
	DSM5745_02137	Putative kinetochore protein spc24. (200 aa)
	DSM5745_02172	Putative Maintenance of ploidy protein mob1. (283 aa)
	DSM5745_02175	WD_REPEATS_REGION domain-containing protein. (1063 aa)
	nudF	Nuclear distribution protein nudF; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs; Belongs to the WD repeat LIS1/nudF family. (441 aa)
	DSM5745_02252	Tubulin-specific chaperone A; Belongs to the TBCA family. (118 aa)
	DSM5745_02297	Nuclear distribution protein nudE. (582 aa)
	DSM5745_02053	Uncharacterized protein. (169 aa)
	DSM5745_02599	Spindle pole body component. (843 aa)
	DSM5745_00049	Interferon-induced GTP-binding protein Mx; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (727 aa)
	DSM5745_00125	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (637 aa)
	DSM5745_00175	Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] (280 aa)
	DSM5745_00301	Spindle pole body component. (910 aa)
	DSM5745_00469	WW domain-containing protein. (276 aa)
	DSM5745_00478	Uncharacterized protein. (825 aa)
	DSM5745_00516	Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (714 aa)
	DSM5745_00501	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (372 aa)
	DSM5745_00552	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (925 aa)
	DSM5745_00661	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (323 aa)
	DSM5745_00150	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (709 aa)
	DSM5745_01065	Uncharacterized protein. (425 aa)
	DSM5745_01088	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1160 aa)
	DSM5745_00540	Uncharacterized protein. (982 aa)
	DSM5745_00983	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (874 aa)
	DSM5745_01354	SprT-like domain-containing protein. (676 aa)
	DSM5745_01366	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (750 aa)
	DSM5745_00910	Uncharacterized protein. (612 aa)
	DSM5745_01524	Uncharacterized protein. (465 aa)
	DSM5745_01383	Uncharacterized protein. (204 aa)
	DSM5745_11460	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (989 aa)
	DSM5745_11320	Uncharacterized protein. (821 aa)
	DSM5745_11189	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (975 aa)
	DSM5745_10804	Ima1_N domain-containing protein. (869 aa)
	DSM5745_10935	Spindle pole body protein An-Cdc31. (251 aa)
	DSM5745_10929	Uncharacterized protein. (1240 aa)
	DSM5745_10769	Uncharacterized protein. (633 aa)
	DSM5745_10682	Uncharacterized protein. (1420 aa)
	DSM5745_10511	Separin. (2038 aa)
	DSM5745_10422	Uncharacterized protein. (94 aa)
	DSM5745_10575	Uncharacterized protein. (465 aa)
	DSM5745_10585	Centromere protein CBF5. (476 aa)
	DSM5745_10060	Dynein heavy chain, cytoplasmic. (4347 aa)
	DSM5745_10029	Uncharacterized protein. (148 aa)
	DSM5745_10227	SUN domain-containing protein. (608 aa)
	DSM5745_10237	Kinesin class 4 (Chromokinesin group); Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1713 aa)
	DSM5745_10199	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
	DSM5745_10279	Uncharacterized protein. (599 aa)
	DSM5745_09691	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (797 aa)
	DSM5745_09450	INCENP_ARK-bind domain-containing protein. (1242 aa)
	DSM5745_09621	CAP-Gly domain-containing protein. (594 aa)
	DSM5745_09607	Dis1 protein AlpA. (884 aa)
	DSM5745_09593	Uncharacterized protein. (240 aa)
	DSM5745_09073	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (831 aa)
	DSM5745_09037	Csm1 domain-containing protein. (517 aa)
	DSM5745_09183	Uncharacterized protein. (88 aa)
	DSM5745_09232	Rad51 domain-containing protein. (423 aa)
	DSM5745_09248	AAA domain-containing protein. (1137 aa)
	DSM5745_08460	Uncharacterized protein. (239 aa)
	DSM5745_08749	DAO domain-containing protein. (191 aa)
	DSM5745_08836	Nuclear movement protein nudC. (198 aa)
	DSM5745_08925	MPN domain-containing protein. (350 aa)
	DSM5745_08930	Uncharacterized protein. (272 aa)
	DSM5745_08164	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (324 aa)
	DSM5745_08284	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
	DSM5745_08159	Calponin-homology (CH) domain-containing protein. (1148 aa)
	DSM5745_08324	Rab-GAP TBC domain-containing protein. (453 aa)
	DSM5745_08257	Uncharacterized protein. (763 aa)
	DSM5745_07432	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (367 aa)
	DSM5745_07615	Septin; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (377 aa)
	DSM5745_07612	Dynein light intermediate chain. (508 aa)
	DSM5745_07486	Uncharacterized protein. (166 aa)
	DSM5745_07734	Non-specific serine/threonine protein kinase. (655 aa)
	DSM5745_07822	Uncharacterized protein. (238 aa)
	DSM5745_06961	DUF2439 domain-containing protein. (366 aa)
	DSM5745_06928	Putative glutathione-dependent formaldehyde-activating enzyme. (198 aa)
	DSM5745_07225	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (452 aa)
	DSM5745_06205	Putative Cell division control protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (342 aa)
	DSM5745_06280	Polarisome component BudA. (1011 aa)
	DSM5745_06337	GFA domain-containing protein. (163 aa)
	DSM5745_06465	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (447 aa)
	DSM5745_06499	Uncharacterized protein; Belongs to the glycosyl hydrolase 17 family. (2592 aa)
	DSM5745_06243	Uncharacterized protein. (74 aa)
	DSM5745_06574	Uncharacterized protein. (1087 aa)
	DSM5745_06591	SH3 domain-containing protein. (724 aa)
	DSM5745_06598	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (922 aa)
	DSM5745_06711	Protein stu1. (1232 aa)
	DSM5745_06678	Uncharacterized protein. (426 aa)
	DSM5745_06700	Spindle pole body component. (949 aa)
	DSM5745_05451	Uncharacterized protein. (772 aa)
	DSM5745_05408	Uncharacterized protein. (512 aa)
	DSM5745_05504	Spindle pole body component. (766 aa)
	DSM5745_06065	Uncharacterized protein. (293 aa)
	DSM5745_05896	Uncharacterized protein. (1788 aa)
	DSM5745_05922	Uncharacterized protein. (315 aa)
	DSM5745_06072	Uncharacterized protein. (356 aa)
	DSM5745_06066	Uncharacterized protein. (384 aa)
	DSM5745_06063	Putative Short-chain dehydrogenase. (262 aa)
	DSM5745_04573	Calmodulin; Belongs to the calmodulin family. (173 aa)
	DSM5745_04715	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (806 aa)
	DSM5745_04760	Uncharacterized protein. (915 aa)
	DSM5745_04770	Protein kinase domain-containing protein. (573 aa)
	DSM5745_04849	Protein kinase domain-containing protein. (260 aa)
	DSM5745_04878	Uncharacterized protein. (990 aa)
	DSM5745_05209	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (462 aa)
	DSM5745_05193	Serine/threonine-protein kinase. (1124 aa)
	DSM5745_05290	CAP-Gly domain-containing protein. (665 aa)
	DSM5745_05344	Uncharacterized protein. (743 aa)
	DSM5745_05315	Uncharacterized protein. (689 aa)
	DSM5745_03983	Protein kinase domain-containing protein. (278 aa)
	DSM5745_04075	Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (519 aa)
	DSM5745_04202	Uncharacterized protein. (724 aa)
	DSM5745_04300	Uncharacterized protein. (144 aa)
	DSM5745_04184	Checkpoint protein; Belongs to the HUS1 family. (399 aa)

Your Current Organism:

Aspergillus mulundensis

NCBI taxonomy Id: 1810919
Other names: A. mulundensis, Aspergillus mulundensis Bills and Frisvad, 2015, Aspergillus sp. AJC-2016d, Aspergillus sp. QY-2015, Aspergillus sydowii var. GB-2015, Aspergillus sydowii var. mulundensis, CBS 140610, DSM 5745, DSMZ 5745, DTO 316-C9, IBT 33104

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DSM5745_00049	DSM5745_00150	A0A3D8T2D7	A0A3D8T4A5	Interferon-induced GTP-binding protein Mx; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.663
DSM5745_00049	DSM5745_06598	A0A3D8T2D7	A0A3D8RRN4	Interferon-induced GTP-binding protein Mx; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.655
DSM5745_00049	DSM5745_09691	A0A3D8T2D7	A0A3D8QRK9	Interferon-induced GTP-binding protein Mx; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.756
DSM5745_00049	DSM5745_11189	A0A3D8T2D7	A0A3D8QAW1	Interferon-induced GTP-binding protein Mx; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.412
DSM5745_00125	DSM5745_00501	A0A3D8T2M4	A0A3D8T3T1	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.614
DSM5745_00125	DSM5745_00661	A0A3D8T2M4	A0A3D8T490	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	0.614
DSM5745_00125	DSM5745_00910	A0A3D8T2M4	A0A3D8T6E7	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.	Uncharacterized protein.	0.998
DSM5745_00125	DSM5745_00983	A0A3D8T2M4	A0A3D8T5F0	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.811
DSM5745_00125	DSM5745_03142	A0A3D8T2M4	A0A3D8SJJ8	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.	Tyrosine-protein phosphatase cdcA.	0.404
DSM5745_00125	DSM5745_04770	A0A3D8T2M4	A0A3D8S4I1	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.	Protein kinase domain-containing protein.	0.614
DSM5745_00125	DSM5745_05193	A0A3D8T2M4	A0A3D8S5V3	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.	Serine/threonine-protein kinase.	0.720
DSM5745_00125	DSM5745_05209	A0A3D8T2M4	A0A3D8S5T0	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	0.982
DSM5745_00125	DSM5745_05408	A0A3D8T2M4	A0A3D8RX37	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.	Uncharacterized protein.	0.555
DSM5745_00125	DSM5745_05896	A0A3D8T2M4	A0A3D8RYV8	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.	Uncharacterized protein.	0.726
DSM5745_00125	DSM5745_05922	A0A3D8T2M4	A0A3D8RYX9	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.	Uncharacterized protein.	0.460
DSM5745_00125	DSM5745_08164	A0A3D8T2M4	A0A3D8R9C0	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.	0.840
DSM5745_00125	DSM5745_10511	A0A3D8T2M4	A0A3D8QJ78	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.	Separin.	0.719
DSM5745_00150	DSM5745_00049	A0A3D8T4A5	A0A3D8T2D7	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Interferon-induced GTP-binding protein Mx; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.663
DSM5745_00150	DSM5745_04715	A0A3D8T4A5	A0A3D8S4F6	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.663
DSM5745_00150	DSM5745_06598	A0A3D8T4A5	A0A3D8RRN4	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.573

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