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DSM5745_02194 DSM5745_02194 DSM5745_11332 DSM5745_11332 YTM1 YTM1 DSM5745_11328 DSM5745_11328 DSM5745_11185 DSM5745_11185 DSM5745_11061 DSM5745_11061 DSM5745_11090 DSM5745_11090 DSM5745_10781 DSM5745_10781 TIF6 TIF6 DSM5745_10568 DSM5745_10568 DSM5745_10054 DSM5745_10054 DSM5745_10107 DSM5745_10107 SPB1 SPB1 DSM5745_10177 DSM5745_10177 DSM5745_10176 DSM5745_10176 DSM5745_10330 DSM5745_10330 DSM5745_09613 DSM5745_09613 DSM5745_08671 DSM5745_08671 DSM5745_07960 DSM5745_07960 DSM5745_08083 DSM5745_08083 DSM5745_08153 DSM5745_08153 DSM5745_08248 DSM5745_08248 DSM5745_08132 DSM5745_08132 DSM5745_08247 DSM5745_08247 DSM5745_08297 DSM5745_08297 DSM5745_08292 DSM5745_08292 NAT10 NAT10 DSM5745_07597 DSM5745_07597 DSM5745_07056 DSM5745_07056 DSM5745_07377 DSM5745_07377 DSM5745_07412 DSM5745_07412 ERB1 ERB1 DSM5745_06238 DSM5745_06238 DSM5745_06290 DSM5745_06290 DSM5745_06358 DSM5745_06358 DSM5745_06478 DSM5745_06478 DSM5745_06396 DSM5745_06396 DSM5745_06490 DSM5745_06490 DSM5745_06416 DSM5745_06416 DSM5745_05472 DSM5745_05472 DSM5745_05614 DSM5745_05614 DSM5745_05383 DSM5745_05383 DSM5745_06010 DSM5745_06010 DSM5745_04895 DSM5745_04895 DSM5745_04966 DSM5745_04966 DSM5745_05222 DSM5745_05222 DSM5745_05292 DSM5745_05292 DSM5745_05337 DSM5745_05337 DSM5745_04115 DSM5745_04115 DSM5745_04188 DSM5745_04188 DSM5745_04319 DSM5745_04319 DSM5745_04220 DSM5745_04220 DSM5745_04064 DSM5745_04064 DSM5745_03098 DSM5745_03098 DSM5745_03432 DSM5745_03432 DSM5745_03522 DSM5745_03522 DSM5745_03406 DSM5745_03406 DSM5745_03533 DSM5745_03533 DSM5745_03735 DSM5745_03735 DSM5745_03807 DSM5745_03807 DSM5745_03789 DSM5745_03789 DSM5745_03280 DSM5745_03280 DSM5745_03840 DSM5745_03840 DSM5745_01622 DSM5745_01622 DSM5745_01762 DSM5745_01762 DSM5745_01830 DSM5745_01830 DSM5745_01864 DSM5745_01864 DSM5745_02062 DSM5745_02062 DSM5745_02050 DSM5745_02050 DSM5745_01996 DSM5745_01996 DSM5745_02147 DSM5745_02147 DSM5745_00912 DSM5745_00912 DSM5745_01059 DSM5745_01059 DSM5745_00610 DSM5745_00610 NOP7 NOP7 DSM5745_01252 DSM5745_01252 DSM5745_01497 DSM5745_01497 DSM5745_01340 DSM5745_01340 DSM5745_02146 DSM5745_02146 DSM5745_02597 DSM5745_02597 DSM5745_02608 DSM5745_02608 DSM5745_00397 DSM5745_00397 DSM5745_00489 DSM5745_00489 DSM5745_00482 DSM5745_00482 DSM5745_00544 DSM5745_00544 DSM5745_00604 DSM5745_00604 DSM5745_00894 DSM5745_00894
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DSM5745_02194Midasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits; Belongs to the midasin family. (4917 aa)
DSM5745_11332WD_REPEATS_REGION domain-containing protein. (619 aa)
YTM1Ribosome biogenesis protein YTM1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (483 aa)
DSM5745_11328WD_REPEATS_REGION domain-containing protein. (977 aa)
DSM5745_11185Uncharacterized protein. (385 aa)
DSM5745_11061Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (365 aa)
DSM5745_11090U3 small nucleolar ribonucleoprotein protein MPP10; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the MPP10 family. (683 aa)
DSM5745_10781WD_REPEATS_REGION domain-containing protein. (771 aa)
TIF6Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export; Belongs to the eIF-6 family. (247 aa)
DSM5745_10568Brix domain-containing protein. (435 aa)
DSM5745_10054RIO1 family protein kinase. (657 aa)
DSM5745_10107Uncharacterized protein. (378 aa)
SPB1AdoMet-dependent rRNA methyltransferase SPB1; Required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily. (813 aa)
DSM5745_10177Uncharacterized protein. (449 aa)
DSM5745_10176Uncharacterized protein. (359 aa)
DSM5745_10330PINc domain-containing protein. (187 aa)
DSM5745_09613C2H2-type domain-containing protein. (112 aa)
DSM5745_0867160S ribosome subunit biogenesis protein NIP7; Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family. (188 aa)
DSM5745_07960RNA helicase. (808 aa)
DSM5745_08083Uncharacterized protein. (958 aa)
DSM5745_08153Multiple RNA-binding-containing protein 1. (827 aa)
DSM5745_08248Brix domain-containing protein. (359 aa)
DSM5745_08132HMG box domain-containing protein. (295 aa)
DSM5745_08247Uncharacterized protein. (356 aa)
DSM5745_08297WD_REPEATS_REGION domain-containing protein. (962 aa)
DSM5745_08292Uncharacterized protein. (321 aa)
NAT10RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (1067 aa)
DSM5745_07597WD_REPEATS_REGION domain-containing protein. (541 aa)
DSM5745_07056Nucleolar protein 16. (232 aa)
DSM5745_07377WD_REPEATS_REGION domain-containing protein. (580 aa)
DSM5745_07412ATP-dependent RNA helicase dbp3; Belongs to the DEAD box helicase family. (491 aa)
ERB1Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (785 aa)
DSM5745_06238Uncharacterized protein. (729 aa)
DSM5745_06290Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (143 aa)
DSM5745_06358Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (263 aa)
DSM5745_06478Uncharacterized protein. (321 aa)
DSM5745_06396PUM-HD domain-containing protein. (707 aa)
DSM5745_06490Sas10 domain-containing protein. (643 aa)
DSM5745_06416CP-type G domain-containing protein. (543 aa)
DSM5745_05472Uncharacterized protein. (1815 aa)
DSM5745_05614Uncharacterized protein. (480 aa)
DSM5745_05383NUC153 domain-containing protein. (789 aa)
DSM5745_06010Nucleolar complex-associated protein 3; Required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm. Belongs to the CBF/MAK21 family. (689 aa)
DSM5745_04895Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily. (560 aa)
DSM5745_04966BUD22 domain-containing protein. (481 aa)
DSM5745_05222Putative CCAAT-box-binding transcription factor. (570 aa)
DSM5745_05292Uncharacterized protein. (402 aa)
DSM5745_05337Uncharacterized protein. (914 aa)
DSM5745_04115Uncharacterized protein. (648 aa)
DSM5745_04188Protein MAK16; Belongs to the MAK16 family. (321 aa)
DSM5745_04319Uncharacterized protein. (488 aa)
DSM5745_04220Uncharacterized protein. (1211 aa)
DSM5745_04064Uncharacterized protein. (404 aa)
DSM5745_03098Uncharacterized protein. (393 aa)
DSM5745_03432Nop domain-containing protein. (510 aa)
DSM5745_03522RNA helicase. (639 aa)
DSM5745_03406HAD_SAK_1 domain-containing protein. (571 aa)
DSM5745_03533Nucleolar protein 58. (581 aa)
DSM5745_03735rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (404 aa)
DSM5745_03807Uncharacterized protein. (363 aa)
DSM5745_03789S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (260 aa)
DSM5745_03280Ribosome biogenesis protein nsa2. (332 aa)
DSM5745_03840U3 small nucleolar RNA-associated protein 22. (1106 aa)
DSM5745_01622Brix domain-containing protein. (302 aa)
DSM5745_01762Uncharacterized protein. (318 aa)
DSM5745_01830U3 small nucleolar RNA-associated protein 11; Involved in nucleolar processing of pre-18S ribosomal RNA. (285 aa)
DSM5745_01864Uncharacterized protein. (804 aa)
DSM5745_02062Bms1-type G domain-containing protein. (1181 aa)
DSM5745_02050Uncharacterized protein; Belongs to the DEAD box helicase family. (449 aa)
DSM5745_01996Uncharacterized protein. (764 aa)
DSM5745_02147Bms1-type G domain-containing protein. (808 aa)
DSM5745_00912KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (266 aa)
DSM5745_01059DRIM domain-containing protein. (2638 aa)
DSM5745_00610WD_REPEATS_REGION domain-containing protein. (447 aa)
NOP7Pescadillo homolog; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (675 aa)
DSM5745_01252WD_REPEATS_REGION domain-containing protein. (925 aa)
DSM5745_01497AB hydrolase-1 domain-containing protein. (330 aa)
DSM5745_01340Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (219 aa)
DSM5745_02146WD_REPEATS_REGION domain-containing protein. (534 aa)
DSM5745_02597KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. (361 aa)
DSM5745_02608Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (655 aa)
DSM5745_00397WD_REPEATS_REGION domain-containing protein. (901 aa)
DSM5745_0048920S-pre-rRNA D-site endonuclease NOB1; Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm. Belongs to the NOB1 family. (430 aa)
DSM5745_00482Uncharacterized protein. (283 aa)
DSM5745_00544Uncharacterized protein. (1040 aa)
DSM5745_00604Brix domain-containing protein. (445 aa)
DSM5745_00894Kri1_C domain-containing protein. (590 aa)
Your Current Organism:
Aspergillus mulundensis
NCBI taxonomy Id: 1810919
Other names: A. mulundensis, Aspergillus mulundensis Bills and Frisvad, 2015, Aspergillus sp. AJC-2016d, Aspergillus sp. QY-2015, Aspergillus sydowii var. GB-2015, Aspergillus sydowii var. mulundensis, CBS 140610, DSM 5745, DSMZ 5745, DTO 316-C9, IBT 33104
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