STRINGSTRING
DSM5745_02758 DSM5745_02758 YTM1 YTM1 DSM5745_10823 DSM5745_10823 TIF6 TIF6 DSM5745_10276 DSM5745_10276 DSM5745_09098 DSM5745_09098 GUF1 GUF1 DSM5745_08229 DSM5745_08229 DSM5745_07647 DSM5745_07647 DSM5745_07009 DSM5745_07009 DSM5745_07026 DSM5745_07026 ERB1 ERB1 DSM5745_06364 DSM5745_06364 DSM5745_06238 DSM5745_06238 DSM5745_06612 DSM5745_06612 DSM5745_05385 DSM5745_05385 DSM5745_05712 DSM5745_05712 DSM5745_06120 DSM5745_06120 DSM5745_04943 DSM5745_04943 DSM5745_05363 DSM5745_05363 DSM5745_04171 DSM5745_04171 DSM5745_02795 DSM5745_02795 DSM5745_03025 DSM5745_03025 DSM5745_03401 DSM5745_03401 DSM5745_03417 DSM5745_03417 DSM5745_03296 DSM5745_03296 DSM5745_03459 DSM5745_03459 DSM5745_03547 DSM5745_03547 DSM5745_03426 DSM5745_03426 DSM5745_01728 DSM5745_01728 DSM5745_01939 DSM5745_01939 DSM5745_01966 DSM5745_01966 DSM5745_02066 DSM5745_02066 DSM5745_02360 DSM5745_02360 DSM5745_02637 DSM5745_02637 DSM5745_02672 DSM5745_02672 DSM5745_02660 DSM5745_02660 DSM5745_02665 DSM5745_02665 DSM5745_00682 DSM5745_00682 NOP7 NOP7 DSM5745_00840 DSM5745_00840 DSM5745_00870 DSM5745_00870
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DSM5745_02758Eukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner. (657 aa)
YTM1Ribosome biogenesis protein YTM1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (483 aa)
DSM5745_10823Uncharacterized protein; Belongs to the eukaryotic ribosomal protein P1/P2 family. (109 aa)
TIF6Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export; Belongs to the eIF-6 family. (247 aa)
DSM5745_10276Tr-type G domain-containing protein. (1077 aa)
DSM5745_09098J domain-containing protein. (449 aa)
GUF1Translation factor GUF1, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner. (662 aa)
DSM5745_08229RING-type domain-containing protein. (772 aa)
DSM5745_07647Uncharacterized protein. (525 aa)
DSM5745_07009WD_REPEATS_REGION domain-containing protein. (341 aa)
DSM5745_07026Plug_translocon domain-containing protein. (478 aa)
ERB1Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (785 aa)
DSM5745_06364Pre-mRNA-processing ATP-dependent RNA helicase prp5. (1174 aa)
DSM5745_06238Uncharacterized protein. (729 aa)
DSM5745_06612Uncharacterized protein. (233 aa)
DSM5745_05385Uncharacterized protein. (191 aa)
DSM5745_05712Putative b-zip transcription factor. (468 aa)
DSM5745_06120RRM domain-containing protein. (503 aa)
DSM5745_0494360S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. (511 aa)
DSM5745_05363RRF domain-containing protein. (259 aa)
DSM5745_04171SRP54 domain-containing protein. (641 aa)
DSM5745_02795Eukaryotic translation initiation factor eIF-1. (311 aa)
DSM5745_03025Uncharacterized protein. (374 aa)
DSM5745_03401Uncharacterized protein. (303 aa)
DSM5745_03417Eukaryotic translation initiation factor 3 subunit K; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (250 aa)
DSM5745_03296Letm1 RBD domain-containing protein. (543 aa)
DSM5745_03459Protein methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (544 aa)
DSM5745_03547Translation initiation factor eIF2 alpha subunit. (308 aa)
DSM5745_03426Uncharacterized protein. (605 aa)
DSM5745_01728RING-type domain-containing protein. (1627 aa)
DSM5745_01939OBG-type G domain-containing protein. (557 aa)
DSM5745_01966Uncharacterized protein. (564 aa)
DSM5745_02066Tr-type G domain-containing protein. (844 aa)
DSM5745_02360Uncharacterized protein. (1165 aa)
DSM5745_02637Ribosomal protein L19; Belongs to the eukaryotic ribosomal protein eL19 family. (2764 aa)
DSM5745_02672MIT domain-containing protein. (1132 aa)
DSM5745_02660Uncharacterized protein. (317 aa)
DSM5745_02665Uncharacterized protein. (334 aa)
DSM5745_00682WD_REPEATS_REGION domain-containing protein. (287 aa)
NOP7Pescadillo homolog; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (675 aa)
DSM5745_00840Eukaryotic translation initiation factor 5A. (114 aa)
DSM5745_00870Signal recognition particle subunit SRP68; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP68 family. (620 aa)
Your Current Organism:
Aspergillus mulundensis
NCBI taxonomy Id: 1810919
Other names: A. mulundensis, Aspergillus mulundensis Bills and Frisvad, 2015, Aspergillus sp. AJC-2016d, Aspergillus sp. QY-2015, Aspergillus sydowii var. GB-2015, Aspergillus sydowii var. mulundensis, CBS 140610, DSM 5745, DSMZ 5745, DTO 316-C9, IBT 33104
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