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MDE1 MDE1 DSM5745_00691 DSM5745_00691 DSM5745_00866 DSM5745_00866 DSM5745_00907 DSM5745_00907 DSM5745_00620 DSM5745_00620 DSM5745_01161 DSM5745_01161 DSM5745_01258 DSM5745_01258 DSM5745_01402 DSM5745_01402 DSM5745_01509 DSM5745_01509 DSM5745_01170 DSM5745_01170 DSM5745_01000 DSM5745_01000 DSM5745_11345 DSM5745_11345 DSM5745_11125 DSM5745_11125 DSM5745_11109 DSM5745_11109 MRI1 MRI1 DSM5745_11065 DSM5745_11065 DSM5745_10978 DSM5745_10978 DSM5745_10685 DSM5745_10685 DSM5745_10360 DSM5745_10360 DSM5745_10598 DSM5745_10598 DSM5745_10594 DSM5745_10594 DSM5745_10196 DSM5745_10196 DSM5745_10290 DSM5745_10290 DSM5745_10347 DSM5745_10347 DSM5745_09786 DSM5745_09786 DSM5745_09722 DSM5745_09722 DSM5745_09392 DSM5745_09392 DSM5745_09395 DSM5745_09395 DSM5745_09426 DSM5745_09426 DSM5745_09068 DSM5745_09068 DSM5745_09219 DSM5745_09219 DSM5745_09040 DSM5745_09040 DSM5745_09282 DSM5745_09282 DSM5745_09080 DSM5745_09080 DSM5745_09286 DSM5745_09286 DSM5745_08467 DSM5745_08467 DSM5745_08509 DSM5745_08509 DSM5745_08822 DSM5745_08822 DSM5745_08756 DSM5745_08756 DSM5745_08202 DSM5745_08202 DSM5745_07479 DSM5745_07479 DSM5745_07473 DSM5745_07473 DSM5745_07592 DSM5745_07592 DSM5745_07782 DSM5745_07782 DSM5745_07060 DSM5745_07060 DSM5745_07136 DSM5745_07136 DSM5745_06218 DSM5745_06218 DSM5745_06369 DSM5745_06369 DSM5745_06409 DSM5745_06409 DSM5745_06777 DSM5745_06777 DSM5745_06875 DSM5745_06875 DSM5745_06776 DSM5745_06776 DSM5745_05575 DSM5745_05575 DSM5745_05558 DSM5745_05558 DSM5745_05607 DSM5745_05607 DSM5745_05729 DSM5745_05729 DSM5745_05734 DSM5745_05734 DSM5745_05764 DSM5745_05764 DSM5745_05937 DSM5745_05937 DSM5745_05832 DSM5745_05832 DSM5745_06078 DSM5745_06078 DSM5745_06155 DSM5745_06155 DSM5745_04629 DSM5745_04629 DSM5745_04973 DSM5745_04973 DSM5745_05189 DSM5745_05189 DSM5745_05244 DSM5745_05244 DSM5745_05323 DSM5745_05323 DSM5745_05347 DSM5745_05347 DSM5745_03863 DSM5745_03863 DSM5745_04096 DSM5745_04096 DSM5745_04145 DSM5745_04145 DSM5745_04159 DSM5745_04159 DSM5745_04040 DSM5745_04040 DSM5745_04303 DSM5745_04303 DSM5745_04468 DSM5745_04468 DSM5745_04466 DSM5745_04466 DSM5745_04462 DSM5745_04462 ADI1 ADI1 DSM5745_04469 DSM5745_04469 DSM5745_04470 DSM5745_04470 DSM5745_03112 DSM5745_03112 DSM5745_03249 DSM5745_03249 DSM5745_03196 DSM5745_03196 DSM5745_03216 DSM5745_03216 DSM5745_02850 DSM5745_02850 DSM5745_03555 DSM5745_03555 DSM5745_03638 DSM5745_03638 DSM5745_03735 DSM5745_03735 DSM5745_03841 DSM5745_03841 DSM5745_03839 DSM5745_03839 DSM5745_03766 DSM5745_03766 DSM5745_03796 DSM5745_03796 DSM5745_03750 DSM5745_03750 DSM5745_01662 DSM5745_01662 DSM5745_01656 DSM5745_01656 DSM5745_02057 DSM5745_02057 DSM5745_02077 DSM5745_02077 DSM5745_02267 DSM5745_02267 DSM5745_02298 DSM5745_02298 DSM5745_02394 DSM5745_02394 DSM5745_02425 DSM5745_02425 DSM5745_02499 DSM5745_02499 DSM5745_02659 DSM5745_02659 DSM5745_00041 DSM5745_00041 DSM5745_00189 DSM5745_00189 DSM5745_00161 DSM5745_00161 DSM5745_00276 DSM5745_00276 DSM5745_00305 DSM5745_00305 DSM5745_00355 DSM5745_00355 DSM5745_00356 DSM5745_00356 DSM5745_00383 DSM5745_00383 DSM5745_00461 DSM5745_00461 DSM5745_00523 DSM5745_00523
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MDE1Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). (240 aa)
DSM5745_00691PLP-dependent transferase. (555 aa)
DSM5745_00866Rhodanese domain-containing protein. (228 aa)
DSM5745_00907Cysteine dioxygenase. (238 aa)
DSM5745_00620PALP domain-containing protein. (360 aa)
DSM5745_01161Uncharacterized protein; Belongs to the LDH/MDH superfamily. (312 aa)
DSM5745_01258Aspartate aminotransferase. (420 aa)
DSM5745_01402Aminotran_1_2 domain-containing protein. (414 aa)
DSM5745_01509Uncharacterized protein. (253 aa)
DSM5745_01170PALP domain-containing protein. (444 aa)
DSM5745_01000Fungal transcription factor regulatory middle homology region. (551 aa)
DSM5745_11345Cobalamin-independent methionine synthase. (774 aa)
DSM5745_11125Zn(2)-C6 fungal-type domain-containing protein. (588 aa)
DSM5745_11109Uncharacterized protein; Belongs to the LDH/MDH superfamily. (330 aa)
MRI1Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily. (379 aa)
DSM5745_11065Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (411 aa)
DSM5745_10978Aminotran_1_2 domain-containing protein. (497 aa)
DSM5745_10685Uncharacterized protein. (397 aa)
DSM5745_10360Uncharacterized protein. (461 aa)
DSM5745_10598D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (470 aa)
DSM5745_10594Aspartokinase. (523 aa)
DSM5745_10196Mac domain-containing protein. (239 aa)
DSM5745_10290Uncharacterized protein. (412 aa)
DSM5745_10347UNC93-like protein. (457 aa)
DSM5745_09786Uncharacterized protein. (430 aa)
DSM5745_09722PALP domain-containing protein. (351 aa)
DSM5745_09392Aminotran_1_2 domain-containing protein. (404 aa)
DSM5745_09395Uncharacterized protein. (301 aa)
DSM5745_09426Uncharacterized protein. (484 aa)
DSM5745_09068Rhodanese domain-containing protein. (520 aa)
DSM5745_09219Aldo_ket_red domain-containing protein. (322 aa)
DSM5745_09040Uncharacterized protein. (432 aa)
DSM5745_09282Uncharacterized protein. (175 aa)
DSM5745_09080Putative branched-chain-amino-acid aminotransferase TOXF. (306 aa)
DSM5745_09286Uncharacterized protein. (466 aa)
DSM5745_08467Uncharacterized protein. (241 aa)
DSM5745_08509Mac domain-containing protein. (223 aa)
DSM5745_08822Uncharacterized protein. (590 aa)
DSM5745_08756Uncharacterized protein. (277 aa)
DSM5745_08202Uncharacterized protein. (381 aa)
DSM5745_07479Phytanoyl-CoA dioxygenase family protein. (306 aa)
DSM5745_07473Prefoldin subunit 3; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit alpha family. (193 aa)
DSM5745_07592Uncharacterized protein. (448 aa)
DSM5745_07782Aspartate aminotransferase. (415 aa)
DSM5745_07060GAF domain-containing protein. (191 aa)
DSM5745_07136MARVEL domain-containing protein. (281 aa)
DSM5745_06218Yae1_N domain-containing protein. (191 aa)
DSM5745_06369Adenosylhomocysteinase. (449 aa)
DSM5745_06409S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (388 aa)
DSM5745_06777Zn(2)-C6 fungal-type domain-containing protein. (501 aa)
DSM5745_06875Uncharacterized protein. (231 aa)
DSM5745_06776Acetyltransferase. (218 aa)
DSM5745_05575Homoserine O-acetyltransferase. (482 aa)
DSM5745_05558Cys metabolizm PLP-dependent enzyme. (590 aa)
DSM5745_05607Glutathione synthetase. (516 aa)
DSM5745_05729S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (400 aa)
DSM5745_05734Amino_oxidase domain-containing protein. (682 aa)
DSM5745_05764Aspartate aminotransferase. (426 aa)
DSM5745_05937Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (343 aa)
DSM5745_05832Phosphoserine aminotransferase. (424 aa)
DSM5745_06078APH domain-containing protein. (362 aa)
DSM5745_06155Uncharacterized protein. (547 aa)
DSM5745_04629Aspartate aminotransferase. (429 aa)
DSM5745_04973S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (804 aa)
DSM5745_05189Uncharacterized protein. (382 aa)
DSM5745_05244Cysteine synthase 2. (430 aa)
DSM5745_05323Cystathionine gamma-lyase. (409 aa)
DSM5745_05347Uncharacterized protein. (508 aa)
DSM5745_03863Uncharacterized protein. (191 aa)
DSM5745_04096Transaminase. (407 aa)
DSM5745_04145PALP domain-containing protein. (319 aa)
DSM5745_04159Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (587 aa)
DSM5745_04040Malate dehydrogenase, mitochondrial. (546 aa)
DSM5745_04303Putative Zn(II)2Cys6 transcription factor. (701 aa)
DSM5745_04468Uncharacterized protein. (338 aa)
DSM5745_04466Uncharacterized protein. (280 aa)
DSM5745_04462Uncharacterized protein. (292 aa)
ADI11,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (178 aa)
DSM5745_04469Uncharacterized protein. (260 aa)
DSM5745_04470Uncharacterized protein. (255 aa)
DSM5745_03112Meth_synt_2 domain-containing protein. (400 aa)
DSM5745_03249Mac domain-containing protein. (233 aa)
DSM5745_03196Homoserine dehydrogenase. (368 aa)
DSM5745_03216Uncharacterized protein. (1092 aa)
DSM5745_02850Semialdhyde_dh domain-containing protein. (363 aa)
DSM5745_03555Uncharacterized protein. (665 aa)
DSM5745_03638Uncharacterized protein. (309 aa)
DSM5745_03735rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (404 aa)
DSM5745_03841Cystathionine gamma-synthase. (554 aa)
DSM5745_03839Uncharacterized protein. (1257 aa)
DSM5745_03766Uncharacterized protein. (344 aa)
DSM5745_03796Mac domain-containing protein. (233 aa)
DSM5745_03750Homocysteine S-methyltransferase. (354 aa)
DSM5745_01662PABS domain-containing protein; Belongs to the spermidine/spermine synthase family. (310 aa)
DSM5745_01656Putative Cystathionine beta-lyase. (395 aa)
DSM5745_02057Aminotran_1_2 domain-containing protein. (529 aa)
DSM5745_02077Uncharacterized protein. (510 aa)
DSM5745_02267Microbody (Peroxisome) biogenesis protein peroxin 8. (698 aa)
DSM5745_02298Uncharacterized protein. (388 aa)
DSM5745_02394Aspartate transaminase. (456 aa)
DSM5745_02425Aspartate aminotransferase. (418 aa)
DSM5745_02499Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (400 aa)
DSM5745_02659Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (532 aa)
DSM5745_00041Aminotran_1_2 domain-containing protein. (528 aa)
DSM5745_00189Cysteine synthase 1. (370 aa)
DSM5745_00161RmlD_sub_bind domain-containing protein. (305 aa)
DSM5745_00276Uncharacterized protein. (308 aa)
DSM5745_00305Uncharacterized protein. (484 aa)
DSM5745_00355Uncharacterized protein. (185 aa)
DSM5745_00356Putative Branched-chain amino acid aminotransferase lyase. (321 aa)
DSM5745_00383Aminotran_1_2 domain-containing protein. (591 aa)
DSM5745_00461Uncharacterized protein. (501 aa)
DSM5745_00523Homocysteine synthase. (437 aa)
Your Current Organism:
Aspergillus mulundensis
NCBI taxonomy Id: 1810919
Other names: A. mulundensis, Aspergillus mulundensis Bills and Frisvad, 2015, Aspergillus sp. AJC-2016d, Aspergillus sp. QY-2015, Aspergillus sydowii var. GB-2015, Aspergillus sydowii var. mulundensis, CBS 140610, DSM 5745, DSMZ 5745, DTO 316-C9, IBT 33104
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