(43 nodes) Phenylalanine, tyrosine and tryptophan biosynthesis network (Aspergillus mulundensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DSM5745_11028	Uncharacterized protein. (362 aa)
	DSM5745_11027	Fungal_trans domain-containing protein. (1485 aa)
	DSM5745_11058	Uncharacterized protein. (99 aa)
	DSM5745_10843	Phospho-2-dehydro-3-deoxyheptonate aldolase. (362 aa)
	DSM5745_10809	Chorismate synthase. (410 aa)
	DSM5745_10224	Chorismate mutase. (267 aa)
	DSM5745_09707	Uncharacterized protein. (796 aa)
	DSM5745_09392	Aminotran_1_2 domain-containing protein. (404 aa)
	DSM5745_09528	PALP domain-containing protein. (441 aa)
	DSM5745_09634	FtsJ domain-containing protein. (391 aa)
	DSM5745_08236	Uncharacterized protein. (1293 aa)
	DSM5745_08237	Phospho-2-dehydro-3-deoxyheptonate aldolase. (374 aa)
	DSM5745_07782	Aspartate aminotransferase. (415 aa)
	DSM5745_07928	Uncharacterized protein. (699 aa)
	DSM5745_07276	Uncharacterized protein. (100 aa)
	DSM5745_06317	Shikimate_dh_N domain-containing protein. (312 aa)
	DSM5745_06318	Uncharacterized protein. (851 aa)
	DSM5745_06549	Quinate dehydrogenase. (329 aa)
	qutE	Catabolic 3-dehydroquinase; Is involved in the catabolism of quinate. Allows the utilization of quinate as carbon source via the beta-ketoadipate pathway; Belongs to the type-II 3-dehydroquinase family. (153 aa)
	DSM5745_06542	Quinate repressor protein. (899 aa)
	DSM5745_06799	DHQ_synthase domain-containing protein. (492 aa)
	DSM5745_05734	Amino_oxidase domain-containing protein. (682 aa)
	DSM5745_05764	Aspartate aminotransferase. (426 aa)
	DSM5745_04629	Aspartate aminotransferase. (429 aa)
	DSM5745_04902	Phospho-2-dehydro-3-deoxyheptonate aldolase; Belongs to the class-II DAHP synthase family. (482 aa)
	DSM5745_04913	Uncharacterized protein. (215 aa)
	DSM5745_01624	Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities. (769 aa)
	DSM5745_01682	3-phosphoshikimate 1-carboxyvinyltransferase; The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis. In the 2nd section; belongs to the EPSP synthase family. In the 4th section; belongs to the type-I 3-dehydroquinase family. In the N-terminal section; belongs to the dehydroquinate synthase family. (1583 aa)
	DSM5745_01807	Aminotran_1_2 domain-containing protein. (441 aa)
	DSM5745_01716	Aminotran_1_2 domain-containing protein. (427 aa)
	DSM5745_02057	Aminotran_1_2 domain-containing protein. (529 aa)
	DSM5745_02129	Tryptophan synthase. (723 aa)
	DSM5745_02394	Aspartate transaminase. (456 aa)
	DSM5745_02425	Aspartate aminotransferase. (418 aa)
	DSM5745_02496	Prephenate dehydrogenase [NADP(+)]; Belongs to the prephenate/arogenate dehydrogenase family. (437 aa)
	DSM5745_00041	Aminotran_1_2 domain-containing protein. (528 aa)
	DSM5745_00218	SnoaL-like domain-containing protein. (237 aa)
	DSM5745_00383	Aminotran_1_2 domain-containing protein. (591 aa)
	DSM5745_00691	PLP-dependent transferase. (555 aa)
	DSM5745_01065	Uncharacterized protein. (425 aa)
	DSM5745_01258	Aspartate aminotransferase. (420 aa)
	DSM5745_01404	Anthranilate synthetase. (515 aa)
	DSM5745_01478	Uncharacterized protein. (427 aa)

Your Current Organism:

Aspergillus mulundensis

NCBI taxonomy Id: 1810919
Other names: A. mulundensis, Aspergillus mulundensis Bills and Frisvad, 2015, Aspergillus sp. AJC-2016d, Aspergillus sp. QY-2015, Aspergillus sydowii var. GB-2015, Aspergillus sydowii var. mulundensis, CBS 140610, DSM 5745, DSMZ 5745, DTO 316-C9, IBT 33104

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DSM5745_00041	DSM5745_00691	A0A3D8T2I1	A0A3D8T4B8	Aminotran_1_2 domain-containing protein.	PLP-dependent transferase.	0.732
DSM5745_00041	DSM5745_01065	A0A3D8T2I1	A0A3D8T5B3	Aminotran_1_2 domain-containing protein.	Uncharacterized protein.	0.720
DSM5745_00041	DSM5745_01258	A0A3D8T2I1	A0A3D8T5U0	Aminotran_1_2 domain-containing protein.	Aspartate aminotransferase.	0.741
DSM5745_00041	DSM5745_01404	A0A3D8T2I1	A0A3D8T681	Aminotran_1_2 domain-containing protein.	Anthranilate synthetase.	0.742
DSM5745_00041	DSM5745_01624	A0A3D8T2I1	A0A3D8SU67	Aminotran_1_2 domain-containing protein.	Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities.	0.916
DSM5745_00041	DSM5745_01682	A0A3D8T2I1	A0A3D8SUC4	Aminotran_1_2 domain-containing protein.	3-phosphoshikimate 1-carboxyvinyltransferase; The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis. In the 2nd section; belongs to the EPSP synthase family. In the 4th section; belongs to the type-I 3-dehydroquinase family. In the N-terminal section; belongs to the dehydroquinate synthase family.	0.417
DSM5745_00041	DSM5745_01716	A0A3D8T2I1	A0A3D8SUT4	Aminotran_1_2 domain-containing protein.	Aminotran_1_2 domain-containing protein.	0.812
DSM5745_00041	DSM5745_02057	A0A3D8T2I1	A0A3D8SVE0	Aminotran_1_2 domain-containing protein.	Aminotran_1_2 domain-containing protein.	0.792
DSM5745_00041	DSM5745_02129	A0A3D8T2I1	A0A3D8SVQ5	Aminotran_1_2 domain-containing protein.	Tryptophan synthase.	0.857
DSM5745_00041	DSM5745_02394	A0A3D8T2I1	A0A3D8SWH9	Aminotran_1_2 domain-containing protein.	Aspartate transaminase.	0.823
DSM5745_00041	DSM5745_02425	A0A3D8T2I1	A0A3D8SWI8	Aminotran_1_2 domain-containing protein.	Aspartate aminotransferase.	0.822
DSM5745_00041	DSM5745_02496	A0A3D8T2I1	A0A3D8SX31	Aminotran_1_2 domain-containing protein.	Prephenate dehydrogenase [NADP(+)]; Belongs to the prephenate/arogenate dehydrogenase family.	0.832
DSM5745_00041	DSM5745_04629	A0A3D8T2I1	A0A3D8S443	Aminotran_1_2 domain-containing protein.	Aspartate aminotransferase.	0.839
DSM5745_00041	DSM5745_05764	A0A3D8T2I1	A0A3D8RXY2	Aminotran_1_2 domain-containing protein.	Aspartate aminotransferase.	0.749
DSM5745_00041	DSM5745_06799	A0A3D8T2I1	A0A3D8RRU1	Aminotran_1_2 domain-containing protein.	DHQ_synthase domain-containing protein.	0.417
DSM5745_00041	DSM5745_07782	A0A3D8T2I1	A0A3D8RF71	Aminotran_1_2 domain-containing protein.	Aspartate aminotransferase.	0.749
DSM5745_00041	DSM5745_09528	A0A3D8T2I1	A0A3D8QVJ4	Aminotran_1_2 domain-containing protein.	PALP domain-containing protein.	0.849
DSM5745_00041	DSM5745_10224	A0A3D8T2I1	A0A3D8QMQ4	Aminotran_1_2 domain-containing protein.	Chorismate mutase.	0.751
DSM5745_00041	DSM5745_10809	A0A3D8T2I1	A0A3D8QF68	Aminotran_1_2 domain-containing protein.	Chorismate synthase.	0.760
DSM5745_00218	DSM5745_01065	A0A3D8T2W5	A0A3D8T5B3	SnoaL-like domain-containing protein.	Uncharacterized protein.	0.679

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