STRINGSTRING
AND78563.1 AND78563.1 AND78830.1 AND78830.1 AND78831.1 AND78831.1 AND78840.1 AND78840.1 AND78841.1 AND78841.1 AND78842.1 AND78842.1 AND78843.1 AND78843.1 cutC cutC serC serC AND78853.1 AND78853.1 AND78854.1 AND78854.1 AND80403.1 AND80403.1 AND79005.1 AND79005.1 dapA dapA AND79087.1 AND79087.1 AND79139.1 AND79139.1 dapB dapB mmuM mmuM AND79241.1 AND79241.1 thrB thrB AND79268.1 AND79268.1 asd asd dapA-2 dapA-2 AND79390.1 AND79390.1 AND79417.1 AND79417.1 metAA metAA AND79601.1 AND79601.1 metK metK AND80454.1 AND80454.1 AND79808.1 AND79808.1 luxS luxS AND79873.1 AND79873.1 ilvA ilvA AND79948.1 AND79948.1 AND79983.1 AND79983.1 gshAB gshAB AND80089.1 AND80089.1 dapH dapH metK-2 metK-2 AND80262.1 AND80262.1 AND80297.1 AND80297.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AND78563.1Diaminopimelate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (414 aa)
AND78830.1Catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. (364 aa)
AND78831.1Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology. (388 aa)
AND78840.1LysR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family. (288 aa)
AND78841.1Hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (286 aa)
AND78842.1Cystathionine beta-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (389 aa)
AND78843.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (168 aa)
cutCCopper homeostasis protein CutC; Participates in the control of copper homeostasis. Belongs to the CutC family. (210 aa)
serC3-phosphoserine/phosphohydroxythreonine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (363 aa)
AND78853.1GNAT family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (185 aa)
AND78854.1Phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (393 aa)
AND80403.1Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (330 aa)
AND79005.15-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (377 aa)
dapADihydrodipicolinate synthase family protein; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (299 aa)
AND79087.1Phosphoserine phosphatase SerB; Derived by automated computational analysis using gene prediction method: Protein Homology. (215 aa)
AND79139.1Aminotransferase; Associated with arginine deiminase pathway genes; probably functions in arginine catabolism; Derived by automated computational analysis using gene prediction method: Protein Homology. (375 aa)
dapB4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (255 aa)
mmuMConverts homocysteine and S-adenosyl-methionine to methionine and S-adenosyl-homocysteine or S-methyl-methionine and homocysteine to two methionines; Derived by automated computational analysis using gene prediction method: Protein Homology. (316 aa)
AND79241.1Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (428 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (290 aa)
AND79268.15'-methylthioadenosine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (230 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (358 aa)
dapA-24-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (308 aa)
AND79390.1Aminopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (847 aa)
AND79417.1O-acetylhomoserine aminocarboxypropyltransferase; Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; Derived by automated computational analysis using gene prediction method: Protein Homology. (426 aa)
metAAHomoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. (306 aa)
AND79601.15-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (381 aa)
metKMethionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (399 aa)
AND80454.1GAF domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (165 aa)
AND79808.1Cysteine synthase A; Derived by automated computational analysis using gene prediction method: Protein Homology. (309 aa)
luxSS-ribosylhomocysteinase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. (160 aa)
AND79873.1Aspartate kinase; Catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; lysine and threonine sensitive; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (453 aa)
ilvAThreonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (416 aa)
AND79948.1Serine O-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (207 aa)
AND79983.1Dihydrodipicolinate synthase family protein; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (299 aa)
gshABBifunctional glutamate--cysteine ligase/glutathione synthetase; Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine; In the N-terminal section; belongs to the glutamate--cysteine ligase type 1 family. Type 2 subfamily. (754 aa)
AND80089.1N-acetyldiaminopimelate deacetylase; Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate. (375 aa)
dapH2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. (232 aa)
metK-2Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (397 aa)
AND80262.1Catalyzes the transamination of the aromatic amino acid forming a ketoacid; first step in aromatic amino acid degradation in lactococci; Derived by automated computational analysis using gene prediction method: Protein Homology. (391 aa)
AND80297.1Threonine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (495 aa)
Your Current Organism:
Streptococcus pantholopis
NCBI taxonomy Id: 1811193
Other names: CGMCC 1.15667, DSM 102135, S. pantholopis, Streptococcus pantholopis Bai et al. 2016, Streptococcus sp. TA 26, Streptococcus sp. TA 421, strain TA 26
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