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metAA metAA AND79601.1 AND79601.1 thiI thiI metK metK folD folD AND80403.1 AND80403.1 AND79770.1 AND79770.1 AND79808.1 AND79808.1 accA accA accD accD AND79862.1 AND79862.1 AND79928.1 AND79928.1 AND79948.1 AND79948.1 gshAB gshAB AND80064.1 AND80064.1 metK-2 metK-2 AND80327.1 AND80327.1 ackA ackA AND79241.1 AND79241.1 AND79268.1 AND79268.1 asd asd AND79417.1 AND79417.1 AND79562.1 AND79562.1 AND79564.1 AND79564.1 AND79005.1 AND79005.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
metAAHomoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. (306 aa)
AND79601.15-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (381 aa)
thiItRNA sulfurtransferase ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (404 aa)
metKMethionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (399 aa)
folDMethenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (287 aa)
AND80403.1Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (330 aa)
AND79770.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (176 aa)
AND79808.1Cysteine synthase A; Derived by automated computational analysis using gene prediction method: Protein Homology. (309 aa)
accAacetyl-CoA carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (256 aa)
accDacetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (288 aa)
AND79862.1acetyl-CoA carboxylase biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (455 aa)
AND79928.1Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (255 aa)
AND79948.1Serine O-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (207 aa)
gshABBifunctional glutamate--cysteine ligase/glutathione synthetase; Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine; In the N-terminal section; belongs to the glutamate--cysteine ligase type 1 family. Type 2 subfamily. (754 aa)
AND80064.1Thiamine pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (210 aa)
metK-2Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (397 aa)
AND80327.1Gamma-glutamylcysteine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (427 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (397 aa)
AND79241.1Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (428 aa)
AND79268.15'-methylthioadenosine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (230 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (358 aa)
AND79417.1O-acetylhomoserine aminocarboxypropyltransferase; Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; Derived by automated computational analysis using gene prediction method: Protein Homology. (426 aa)
AND79562.1Iron ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (462 aa)
AND79564.1Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (322 aa)
AND79005.15-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (377 aa)
Your Current Organism:
Streptococcus pantholopis
NCBI taxonomy Id: 1811193
Other names: CGMCC 1.15667, DSM 102135, S. pantholopis, Streptococcus pantholopis Bai et al. 2016, Streptococcus sp. TA 26, Streptococcus sp. TA 421, strain TA 26
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