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lacD lacD AND78672.1 AND78672.1 AND78674.1 AND78674.1 lacA lacA lacB lacB lacC lacC lacD-2 lacD-2 AND78763.1 AND78763.1 AND78764.1 AND78764.1 lacG lacG AND79050.1 AND79050.1 AND79325.1 AND79325.1 AND79356.1 AND79356.1 AND79358.1 AND79358.1 AND79359.1 AND79359.1 AND79360.1 AND79360.1 pfkA pfkA AND79464.1 AND79464.1 AND80442.1 AND80442.1 AND79528.1 AND79528.1 AND79529.1 AND79529.1 AND79530.1 AND79530.1 AND79748.1 AND79748.1 gatC gatC AND79999.1 AND79999.1 AND80475.1 AND80475.1 AND80043.1 AND80043.1 AND80044.1 AND80044.1 AND80045.1 AND80045.1 AND80077.1 AND80077.1 AND80086.1 AND80086.1 AND80358.1 AND80358.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
lacDTagatose-bisphosphate aldolase; Catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in Streptococcus pyogenes there are two paralogs of tagatose-bisphosphate aldolase, encoded by lacD1 and lacD2; expression of lacD1 is highly regulated by environmental conditions while lacD2 specializes in an efficient utilization of carbohydrate sources; Derived by automated computational analysis using gene prediction method: Protein Homology. (326 aa)
AND78672.1Sucrose-6-phosphate hydrolase; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family. (487 aa)
AND78674.1Sucrose-6-phosphate hydrolase; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family. (485 aa)
lacAGalactose-6-phosphate isomerase; Catalyzes the interconversion of galactose 6-phosphate to tagatose 6-phosphate; tagatose pathway for galactose utilization; Derived by automated computational analysis using gene prediction method: Protein Homology. (141 aa)
lacBGalactose-6-phosphate isomerase; Catalyzes the interconversion of galactose 6-phosphate to tagatose 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (171 aa)
lacCTagatose-6-phosphate kinase; Catalyzes the formation of tagatose 1,6-bisphosphate from tagatose 6-phosphate and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. (310 aa)
lacD-2Tagatose-bisphosphate aldolase; Catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in Streptococcus pyogenes there are two paralogs of tagatose-bisphosphate aldolase, encoded by lacD1 and lacD2; expression of lacD1 is highly regulated by environmental conditions while lacD2 specializes in an efficient utilization of carbohydrate sources; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa)
AND78763.1PTS lactose transporter subunit IIA; Catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; Derived by automated computational analysis using gene prediction method: Protein Homology. (104 aa)
AND78764.1PTS lactose transporter subunit IIBC; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. (570 aa)
lacG6-phospho-beta-galactosidase; Catalyzes the formation of 6-phospho-galactose from a 6-phospho-beta-galactoside; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 1 family. (467 aa)
AND79050.1UDP-glucose 4-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (337 aa)
AND79325.1Phosphoglucomutase; Catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (571 aa)
AND79356.1PTS N-acetylgalactosamine transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology. (145 aa)
AND79358.1PTS N-acetylgalactosamine transporter subunit IIB; Derived by automated computational analysis using gene prediction method: Protein Homology. (164 aa)
AND79359.1PTS N-acetylgalactosamine transporter subunit IIC; Catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake;involved in N-acetylgalactosamine transport; Derived by automated computational analysis using gene prediction method: Protein Homology. (260 aa)
AND79360.1PTS N-acetylgalactosamine transporter subunit IID; Catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IID with IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport; Derived by automated computational analysis using gene prediction method: Protein Homology. (273 aa)
pfkAATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (337 aa)
AND79464.1UDP-galactopyranose mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (369 aa)
AND80442.1D-galactonate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the mandelate racemase/muconate lactonizing enzyme family. (381 aa)
AND79528.1PTS galactitol transporter subunit IIC; Derived by automated computational analysis using gene prediction method: Protein Homology. (449 aa)
AND79529.1PTS galactitol transporter subunit IIB; Derived by automated computational analysis using gene prediction method: Protein Homology. (93 aa)
AND79530.1PTS galactitol transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology. (168 aa)
AND79748.1Glucokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (323 aa)
gatCPTS galactitol transporter subunit IIC; With GatAB forms a phosphoenolpyruvate-dependent sugar phosphotransferase transporter for galactitol; subunit IIC forms the translocation channel and contains the substrate binding site; Derived by automated computational analysis using gene prediction method: Protein Homology. (422 aa)
AND79999.1PTS galactitol transporter subunit IIB; Derived by automated computational analysis using gene prediction method: Protein Homology. (99 aa)
AND80475.1PTS fructose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology. (157 aa)
AND80043.1PTS galactitol transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology. (156 aa)
AND80044.1PTS galactitol transporter subunit IIB; Derived by automated computational analysis using gene prediction method: Protein Homology. (95 aa)
AND80045.1PTS galactitol transporter subunit IIC; Derived by automated computational analysis using gene prediction method: Protein Homology. (451 aa)
AND80077.1Galactose mutarotase; Converts alpha-aldose to the beta-anomer. (343 aa)
AND80086.1UTP--glucose-1-phosphate uridylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (298 aa)
AND80358.1PTS fructose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology. (144 aa)
Your Current Organism:
Streptococcus pantholopis
NCBI taxonomy Id: 1811193
Other names: CGMCC 1.15667, DSM 102135, S. pantholopis, Streptococcus pantholopis Bai et al. 2016, Streptococcus sp. TA 26, Streptococcus sp. TA 421, strain TA 26
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