STRINGSTRING
KYP11430.1 KYP11430.1 KYP11383.1 KYP11383.1 purL purL KYP11316.1 KYP11316.1 KYP11352.1 KYP11352.1 ihfA ihfA KYP11217.1 KYP11217.1 nrdR nrdR KYP11179.1 KYP11179.1 KYP11076.1 KYP11076.1 KYP11095.1 KYP11095.1 KYP11056.1 KYP11056.1 KYP11020.1 KYP11020.1 truA truA purF purF KYP10972.1 KYP10972.1 KYP10973.1 KYP10973.1 ndk ndk surE surE KYP10712.1 KYP10712.1 purA purA ttcA ttcA KYP10487.1 KYP10487.1 KYP10454.1 KYP10454.1 KYP10230.1 KYP10230.1 KYP10219.1 KYP10219.1 KYP10111.1 KYP10111.1 KYP10074.1 KYP10074.1 A0129_15285 A0129_15285 KYP11452.1 KYP11452.1 KYP11531.1 KYP11531.1 tilS tilS KYP11868.1 KYP11868.1 cysC cysC KYP11986.1 KYP11986.1 ppnP ppnP KYP12119.1 KYP12119.1 purM purM KYP12099.1 KYP12099.1 purK purK purE purE KYP12091.1 KYP12091.1 purH purH KYP12210.1 KYP12210.1 KYP12307.1 KYP12307.1 gmk gmk rph rph KYP12298.1 KYP12298.1 KYP12285.1 KYP12285.1 KYP12284.1 KYP12284.1 KYP12428.1 KYP12428.1 ihfB ihfB KYP12383.1 KYP12383.1 purN purN KYP12529.1 KYP12529.1 prs prs ychF ychF guaB guaB guaA guaA purT purT KYP12591.1 KYP12591.1 KYP12563.1 KYP12563.1 KYP12761.1 KYP12761.1 apaH apaH KYP12691.1 KYP12691.1 KYP12676.1 KYP12676.1 purD purD KYP11424.1 KYP11424.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KYP11430.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (271 aa)
KYP11383.1DNA-binding protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. (90 aa)
purLPhosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. (1347 aa)
KYP11316.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (811 aa)
KYP11352.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (385 aa)
ihfAIntegration host factor subunit alpha; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. (109 aa)
KYP11217.1Magnesium transporter; Acts as a magnesium transporter. (484 aa)
nrdRTranscriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. (170 aa)
KYP11179.1Deoxyguanosinetriphosphate triphosphohydrolase; dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (370 aa)
KYP11076.1Electron transporter RnfB; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa)
KYP11095.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (148 aa)
KYP11056.1Sulfate adenylyltransferase; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (449 aa)
KYP11020.1Sulfate adenylyltransferase small subunit; With CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology. (307 aa)
truAtRNA pseudouridine(38-40) synthase; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (254 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (504 aa)
KYP10972.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (462 aa)
KYP10973.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (477 aa)
ndkNucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (141 aa)
surE5'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (248 aa)
KYP10712.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (158 aa)
purAAdenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (433 aa)
ttcAtRNA 2-thiocytidine biosynthesis protein TtcA; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. (290 aa)
KYP10487.1Alkaline phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (623 aa)
KYP10454.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (261 aa)
KYP10230.1Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (959 aa)
KYP10219.1Ribonucleotide-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (401 aa)
KYP10111.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (157 aa)
KYP10074.1Restriction endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (785 aa)
A0129_15285Transposase; Metagenomic; derived from metagenome: freshwater metagenome. (751 aa)
KYP11452.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (360 aa)
KYP11531.1Rossman fold protein, TIGR00730 family; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LOG family. (188 aa)
tilSHypothetical protein; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (322 aa)
KYP11868.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (259 aa)
cysCAdenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. (199 aa)
KYP11986.1ADP-ribose pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (180 aa)
ppnPHypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. (103 aa)
KYP12119.1Magnesium/cobalt efflux protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (304 aa)
purMPhosphoribosylformylglycinamidine cyclo-ligase; Catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (346 aa)
KYP12099.1Deoxyadenosine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (213 aa)
purK5-(carboxyamino)imidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (391 aa)
purEPhosphoribosylaminoimidazolesuccinocarboxamide synthase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (173 aa)
KYP12091.1Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family. (492 aa)
purHPhosphoribosylaminoimidazolecarboxamide formyltransferase; Involved in de novo purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (530 aa)
KYP12210.1Adenylosuccinate lyase; Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (458 aa)
KYP12307.1Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (742 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (215 aa)
rphRibonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (243 aa)
KYP12298.1Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (209 aa)
KYP12285.1Exopolyphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (499 aa)
KYP12284.1GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (764 aa)
KYP12428.1Serine endopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (355 aa)
ihfBIntegration host factor subunit beta; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. (98 aa)
KYP12383.1Rossman fold protein, TIGR00730 family; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LOG family. (245 aa)
purNPhosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (213 aa)
KYP12529.1Histidine triad nucleotide-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (118 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (317 aa)
ychFGTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (363 aa)
guaBIMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (486 aa)
guaAGMP synthetase; Catalyzes the synthesis of GMP from XMP. (540 aa)
purTPhosphoribosylglycinamide formyltransferase; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (413 aa)
KYP12591.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (359 aa)
KYP12563.1Cell division protein BolA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the BolA/IbaG family. (92 aa)
KYP12761.1Phosphoglucomutase; Catalyzes the interconversion of alpha-D-mannose 1-phosphate to alpha-D-mannose 6-phosphate and alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (463 aa)
apaHDiadenosine tetraphosphatase; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. (281 aa)
KYP12691.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0301 (AlgH) family. (194 aa)
KYP12676.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (436 aa)
purDPhosphoribosylamine--glycine ligase; Catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GARS family. (423 aa)
KYP11424.1Sugar kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (318 aa)
Your Current Organism:
Limnobacter sp. CACIAM66H1
NCBI taxonomy Id: 1813033
Other names: L. sp. CACIAM 66H1, Limnobacter sp. CACIAM 66H1
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