(52 nodes) PKMTs methylate histone lysines, and Nucleosome network (fungal sp. No14919)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	A0A1V1SR72	Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily. (916 aa)
	A0A1V1SRI9	WD_REPEATS_REGION domain-containing protein. (597 aa)
	A0A1V1SRL4	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
	A0A1V1SRT3	Uncharacterized protein. (1175 aa)
	A0A1V1ST84	Chromo domain-containing protein. (298 aa)
	A0A1V1SUL7	Uncharacterized protein. (1599 aa)
	A0A1V1SVQ8	Uncharacterized protein. (1273 aa)
	A0A1V1SW07	WD_REPEATS_REGION domain-containing protein. (440 aa)
	A0A1V1SXC8	DUF2236 domain-containing protein. (478 aa)
	A0A1V1SXD9	Histone H3; Belongs to the histone H3 family. (136 aa)
	A0A1V1SYN5	DUF2236 domain-containing protein. (464 aa)
	A0A1V1T0M7	WD_REPEATS_REGION domain-containing protein. (500 aa)
	A0A1V1T1P9	Chromo domain-containing protein. (1383 aa)
	A0A1V1T2P6	Uncharacterized protein. (1771 aa)
	A0A1V1T2T3	Histone H2A; Belongs to the histone H2A family. (142 aa)
	A0A1V1T3M2	Uncharacterized protein. (839 aa)
	A0A1V1T5I3	BAH domain-containing protein. (419 aa)
	A0A1V1T664	SHNi-TPR domain-containing protein. (488 aa)
	A0A1V1T6W1	Uncharacterized protein. (582 aa)
	A0A1V1T745	Uncharacterized protein. (161 aa)
	A0A1V1T750	B30.2/SPRY domain-containing protein. (609 aa)
	A0A1V1T865	SET domain-containing protein. (401 aa)
	A0A1V1T878	Uncharacterized protein. (1121 aa)
	A0A1V1T940	SET domain-containing protein. (643 aa)
	A0A1V1TAA1	Uncharacterized protein. (369 aa)
	A0A1V1TAJ3	Histone H2A; Belongs to the histone H2A family. (134 aa)
	A0A1V1TAS3	Histone H2B; Belongs to the histone H2B family. (136 aa)
	A0A1V1TBM1	Uncharacterized protein. (165 aa)
	A0A1V1TBS5	WD_REPEATS_REGION domain-containing protein. (503 aa)
	A0A1V1TC44	Uncharacterized protein. (1771 aa)
	A0A1V1TCV5	SET domain-containing protein. (934 aa)
	A0A1V1TDC7	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (124 aa)
	A0A1V1TGI6	Uncharacterized protein. (555 aa)
	A0A1V1TGT3	Uncharacterized protein. (348 aa)
	A0A1V1TGU8	Uncharacterized protein. (102 aa)
	A0A1V1TGY2	Uncharacterized protein. (444 aa)
	A0A1V1TH66	PH domain-containing protein. (824 aa)
	A0A1V1THK0	Uncharacterized protein. (79 aa)
	A0A1V1TK46	WD_REPEATS_REGION domain-containing protein. (474 aa)
	A0A1V1TLF7	Uncharacterized protein. (539 aa)
	A0A1V1TLH5	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. (484 aa)
	A0A1V1TLJ2	Glucanase; Belongs to the glycosyl hydrolase 7 (cellulase C) family. (461 aa)
	A0A1V1TMG9	Uncharacterized protein. (87 aa)
	A0A1V1TNG4	SET domain-containing protein. (710 aa)
	A0A1V1TNI8	PHD-type domain-containing protein. (465 aa)
	A0A1V1TNZ5	H15 domain-containing protein. (224 aa)
	A0A1V1TP85	Uncharacterized protein. (375 aa)
	A0A1V1TRQ3	Histone domain-containing protein. (140 aa)
	A0A1V1TTC7	Uncharacterized protein. (891 aa)
	A0A1V1TTS8	Uncharacterized protein. (166 aa)
	A0A1V1TU29	Histone acetyltransferase type B catalytic subunit; Catalytic component of the histone acetylase B (HAT-B) complex. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair; Belongs to the HAT1 family. (497 aa)
	A0A1V1TUG4	Histone domain-containing protein. (149 aa)

Your Current Organism:

fungal sp. No14919

NCBI taxonomy Id: 1813822
Other names: f. sp. No.14919, fungal sp. No.14919

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A1V1SR72	A0A1V1SRI9	Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.	WD_REPEATS_REGION domain-containing protein.	0.442
A0A1V1SR72	A0A1V1SRL4	Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	0.840
A0A1V1SR72	A0A1V1SRT3	Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.	Uncharacterized protein.	0.825
A0A1V1SR72	A0A1V1ST84	Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.	Chromo domain-containing protein.	0.526
A0A1V1SR72	A0A1V1SUL7	Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.	Uncharacterized protein.	0.734
A0A1V1SR72	A0A1V1SVQ8	Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.	Uncharacterized protein.	0.949
A0A1V1SR72	A0A1V1SW07	Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.	WD_REPEATS_REGION domain-containing protein.	0.682
A0A1V1SR72	A0A1V1SXC8	Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.	DUF2236 domain-containing protein.	0.846
A0A1V1SR72	A0A1V1SXD9	Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.	Histone H3; Belongs to the histone H3 family.	0.940
A0A1V1SR72	A0A1V1SYN5	Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.	DUF2236 domain-containing protein.	0.846
A0A1V1SR72	A0A1V1T0M7	Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.	WD_REPEATS_REGION domain-containing protein.	0.714
A0A1V1SR72	A0A1V1T1P9	Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.	Chromo domain-containing protein.	0.526
A0A1V1SR72	A0A1V1T2P6	Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.	Uncharacterized protein.	0.778
A0A1V1SR72	A0A1V1T2T3	Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.	Histone H2A; Belongs to the histone H2A family.	0.901
A0A1V1SR72	A0A1V1T3M2	Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.	Uncharacterized protein.	0.956
A0A1V1SR72	A0A1V1T5I3	Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.	BAH domain-containing protein.	0.640
A0A1V1SR72	A0A1V1T6W1	Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.	Uncharacterized protein.	0.551
A0A1V1SR72	A0A1V1T745	Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.	Uncharacterized protein.	0.540
A0A1V1SR72	A0A1V1T750	Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.	B30.2/SPRY domain-containing protein.	0.746
A0A1V1SR72	A0A1V1T865	Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.	SET domain-containing protein.	0.794