(35 nodes) Spliceosomal snRNP complex, and Like-Sm (LSM) domain containing protein, LSm4/SmD1/SmD3 network (fungal sp. No14919)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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experimentally determined

Predicted Interactions

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protein homology

Your Input:
	A0A1V1SQ65	Uncharacterized protein. (104 aa)
	LSM8	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (99 aa)
	A0A1V1SRZ3	MPN domain-containing protein. (2373 aa)
	A0A1V1STA8	Tr-type G domain-containing protein. (987 aa)
	A0A1V1SUL8	WD_REPEATS_REGION domain-containing protein. (520 aa)
	A0A1V1SUX5	Small nuclear ribonucleoprotein Sm D3. (115 aa)
	A0A1V1SVY0	Uncharacterized protein. (343 aa)
	A0A1V1SWA7	Uncharacterized protein. (109 aa)
	A0A1V1SWU6	WD_REPEATS_REGION domain-containing protein. (355 aa)
	A0A1V1SXD4	Uncharacterized protein. (491 aa)
	A0A1V1T2Q6	Sm domain-containing protein. (128 aa)
	A0A1V1T2S4	Uncharacterized protein. (117 aa)
	A0A1V1T3U0	Uncharacterized protein. (539 aa)
	A0A1V1T4S6	PSP domain-containing protein. (599 aa)
	A0A1V1T6L9	Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. (94 aa)
	A0A1V1T741	Matrin-type domain-containing protein. (243 aa)
	A0A1V1TBC4	Small nuclear ribonucleoprotein Sm D1; Involved in pre-mRNA splicing. Binds snRNA U1, U2, U4 and U5 which contain a highly conserved structural motif called the Sm binding site; Belongs to the snRNP core protein family. (120 aa)
	A0A1V1TBD4	RRM domain-containing protein. (120 aa)
	A0A1V1TBF6	Uncharacterized protein; Belongs to the DEAD box helicase family. (712 aa)
	A0A1V1TBI1	SF3b1 domain-containing protein. (1222 aa)
	A0A1V1TBW2	Matrin-type domain-containing protein. (502 aa)
	A0A1V1TCG6	U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. (202 aa)
	A0A1V1TCY5	Uncharacterized protein. (1343 aa)
	A0A1V1TDP6	Small nuclear ribonucleoprotein Sm D2. (117 aa)
	A0A1V1TEL6	Pre-mRNA-splicing factor rse1. (1210 aa)
	A0A1V1TGI8	Uncharacterized protein. (248 aa)
	A0A1V1THD9	Nop domain-containing protein. (621 aa)
	A0A1V1TJC8	TPR_REGION domain-containing protein. (935 aa)
	A0A1V1TKT7	Splicing factor subunit; Belongs to the SF3B5 family. (97 aa)
	A0A1V1TND5	RRM domain-containing protein. (377 aa)
	A0A1V1TPI5	Small nuclear ribonucleoprotein G. (101 aa)
	A0A1V1TPN1	Sm domain-containing protein. (209 aa)
	A0A1V1TPV4	Uncharacterized protein. (2219 aa)
	A0A1V1TQ78	Uncharacterized protein. (1130 aa)
	A0A1V1TVP5	Uncharacterized protein. (652 aa)

Your Current Organism:

fungal sp. No14919

NCBI taxonomy Id: 1813822
Other names: f. sp. No.14919, fungal sp. No.14919

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1V1SQ65	A0A1V1SRZ3	A0A1V1SQ65	A0A1V1SRZ3	Uncharacterized protein.	MPN domain-containing protein.	0.996
A0A1V1SQ65	A0A1V1STA8	A0A1V1SQ65	A0A1V1STA8	Uncharacterized protein.	Tr-type G domain-containing protein.	0.997
A0A1V1SQ65	A0A1V1SUL8	A0A1V1SQ65	A0A1V1SUL8	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.946
A0A1V1SQ65	A0A1V1SUX5	A0A1V1SQ65	A0A1V1SUX5	Uncharacterized protein.	Small nuclear ribonucleoprotein Sm D3.	0.981
A0A1V1SQ65	A0A1V1SVY0	A0A1V1SQ65	A0A1V1SVY0	Uncharacterized protein.	Uncharacterized protein.	0.907
A0A1V1SQ65	A0A1V1SWA7	A0A1V1SQ65	A0A1V1SWA7	Uncharacterized protein.	Uncharacterized protein.	0.916
A0A1V1SQ65	A0A1V1SWU6	A0A1V1SQ65	A0A1V1SWU6	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.989
A0A1V1SQ65	A0A1V1SXD4	A0A1V1SQ65	A0A1V1SXD4	Uncharacterized protein.	Uncharacterized protein.	0.967
A0A1V1SQ65	A0A1V1T2Q6	A0A1V1SQ65	A0A1V1T2Q6	Uncharacterized protein.	Sm domain-containing protein.	0.976
A0A1V1SQ65	A0A1V1T2S4	A0A1V1SQ65	A0A1V1T2S4	Uncharacterized protein.	Uncharacterized protein.	0.845
A0A1V1SQ65	A0A1V1T3U0	A0A1V1SQ65	A0A1V1T3U0	Uncharacterized protein.	Uncharacterized protein.	0.904
A0A1V1SQ65	A0A1V1T4S6	A0A1V1SQ65	A0A1V1T4S6	Uncharacterized protein.	PSP domain-containing protein.	0.903
A0A1V1SQ65	A0A1V1T6L9	A0A1V1SQ65	A0A1V1T6L9	Uncharacterized protein.	Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family.	0.980
A0A1V1SQ65	A0A1V1T741	A0A1V1SQ65	A0A1V1T741	Uncharacterized protein.	Matrin-type domain-containing protein.	0.903
A0A1V1SQ65	A0A1V1TBC4	A0A1V1SQ65	A0A1V1TBC4	Uncharacterized protein.	Small nuclear ribonucleoprotein Sm D1; Involved in pre-mRNA splicing. Binds snRNA U1, U2, U4 and U5 which contain a highly conserved structural motif called the Sm binding site; Belongs to the snRNP core protein family.	0.966
A0A1V1SQ65	A0A1V1TBD4	A0A1V1SQ65	A0A1V1TBD4	Uncharacterized protein.	RRM domain-containing protein.	0.470
A0A1V1SQ65	A0A1V1TBF6	A0A1V1SQ65	A0A1V1TBF6	Uncharacterized protein.	Uncharacterized protein; Belongs to the DEAD box helicase family.	0.993
A0A1V1SQ65	A0A1V1TBI1	A0A1V1SQ65	A0A1V1TBI1	Uncharacterized protein.	SF3b1 domain-containing protein.	0.918
A0A1V1SQ65	A0A1V1TBW2	A0A1V1SQ65	A0A1V1TBW2	Uncharacterized protein.	Matrin-type domain-containing protein.	0.912
A0A1V1SQ65	A0A1V1TCG6	A0A1V1SQ65	A0A1V1TCG6	Uncharacterized protein.	U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.	0.599