(20 nodes) Negative regulation of actin filament polymerization network (fungal sp. No14919)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1V1STB7	DUF1708 domain-containing protein. (1015 aa)
	A0A1V1SY35	Uncharacterized protein. (334 aa)
	A0A1V1SZI0	Uncharacterized protein. (676 aa)
	A0A1V1SZU4	Uncharacterized protein. (263 aa)
	A0A1V1T0A9	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (272 aa)
	A0A1V1T5S4	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (279 aa)
	A0A1V1SSG7	RRN9 domain-containing protein. (681 aa)
	A0A1V1T9K8	Uncharacterized protein. (1741 aa)
	A0A1V1TAM2	Uncharacterized protein. (352 aa)
	A0A1V1TB70	WD_REPEATS_REGION domain-containing protein. (622 aa)
	A0A1V1TGG3	Uncharacterized protein. (414 aa)
	A0A1V1THD1	Zn(2)-C6 fungal-type domain-containing protein. (414 aa)
	A0A1V1TL93	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. (137 aa)
	A0A1V1TLM9	Uncharacterized protein. (333 aa)
	A0A1V1TLV1	Uncharacterized protein. (153 aa)
	A0A1V1TRR0	Zn(2)-C6 fungal-type domain-containing protein. (403 aa)
	A0A1V1TRY8	Uncharacterized protein. (281 aa)
	A0A1V1TSI9	Uncharacterized protein. (109 aa)
	A0A1V1TTZ2	Uncharacterized protein. (391 aa)
	A0A1V1TVA8	Uncharacterized protein. (1537 aa)

Your Current Organism:

fungal sp. No14919

NCBI taxonomy Id: 1813822
Other names: f. sp. No.14919, fungal sp. No.14919

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A1V1SSG7	A0A1V1T5S4	RRN9 domain-containing protein.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.947
A0A1V1SSG7	A0A1V1TB70	RRN9 domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.509
A0A1V1SSG7	A0A1V1TLM9	RRN9 domain-containing protein.	Uncharacterized protein.	0.617
A0A1V1STB7	A0A1V1TL93	DUF1708 domain-containing protein.	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.	0.909
A0A1V1SY35	A0A1V1T5S4	Uncharacterized protein.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.406
A0A1V1SY35	A0A1V1TL93	Uncharacterized protein.	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.	0.452
A0A1V1SY35	A0A1V1TLM9	Uncharacterized protein.	Uncharacterized protein.	0.686
A0A1V1SY35	A0A1V1TTZ2	Uncharacterized protein.	Uncharacterized protein.	0.476
A0A1V1SY35	A0A1V1TVA8	Uncharacterized protein.	Uncharacterized protein.	0.476
A0A1V1SZI0	A0A1V1T5S4	Uncharacterized protein.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.947
A0A1V1SZI0	A0A1V1TB70	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.509
A0A1V1SZI0	A0A1V1TLM9	Uncharacterized protein.	Uncharacterized protein.	0.617
A0A1V1SZU4	A0A1V1T5S4	Uncharacterized protein.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.947
A0A1V1SZU4	A0A1V1TB70	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.509
A0A1V1SZU4	A0A1V1TLM9	Uncharacterized protein.	Uncharacterized protein.	0.617
A0A1V1T0A9	A0A1V1T5S4	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.972
A0A1V1T0A9	A0A1V1TB70	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	WD_REPEATS_REGION domain-containing protein.	0.509
A0A1V1T0A9	A0A1V1TLM9	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	Uncharacterized protein.	0.617
A0A1V1T5S4	A0A1V1SSG7	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	RRN9 domain-containing protein.	0.947
A0A1V1T5S4	A0A1V1SY35	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	Uncharacterized protein.	0.406