(95 nodes) Positive regulation of transcription by RNA polymerase II network (fungal sp. No14919)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1V1TN57	Uncharacterized protein. (564 aa)
	A0A1V1TMW6	ANK_REP_REGION domain-containing protein. (1424 aa)
	A0A1V1TMT5	Uncharacterized protein. (804 aa)
	A0A1V1TM64	Abhydrolase_3 domain-containing protein. (537 aa)
	A0A1V1TLV4	Fork-head domain-containing protein. (746 aa)
	A0A1V1TL83	AAA domain-containing protein; Belongs to the AAA ATPase family. (391 aa)
	A0A1V1TL24	GATA-type domain-containing protein. (476 aa)
	A0A1V1TKT5	Uncharacterized protein. (538 aa)
	A0A1V1TKE0	Uncharacterized protein. (588 aa)
	A0A1V1TK65	Uncharacterized protein. (118 aa)
	A0A1V1TJD5	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family. (1421 aa)
	A0A1V1TJ65	Uncharacterized protein. (583 aa)
	A0A1V1TJ05	Uncharacterized protein. (680 aa)
	A0A1V1TJ01	Uncharacterized protein. (140 aa)
	A0A1V1TIY4	YTH domain-containing protein. (637 aa)
	A0A1V1TIK3	Uncharacterized protein. (426 aa)
	A0A1V1THE4	Zn(2)-C6 fungal-type domain-containing protein. (1006 aa)
	A0A1V1TH61	BHLH domain-containing protein. (525 aa)
	A0A1V1TGH8	BHLH domain-containing protein. (481 aa)
	A0A1V1TFX3	RING-type domain-containing protein. (651 aa)
	A0A1V1TDD3	Uncharacterized protein. (565 aa)
	A0A1V1TD58	Beta-lactamase domain-containing protein. (418 aa)
	A0A1V1TD02	TMF_TATA_bd domain-containing protein. (846 aa)
	A0A1V1TCY0	Uncharacterized protein. (150 aa)
	A0A1V1TCH7	HTH cro/C1-type domain-containing protein. (156 aa)
	A0A1V1TBZ3	Uncharacterized protein. (412 aa)
	A0A1V1TBX6	BHLH domain-containing protein. (685 aa)
	A0A1V1TB11	Uncharacterized protein. (671 aa)
	A0A1V1TAV6	SGF29 C-terminal domain-containing protein. (392 aa)
	A0A1V1TA49	GCR1_C domain-containing protein. (391 aa)
	A0A1V1T8Z4	NDT80 domain-containing protein. (680 aa)
	A0A1V1T8M8	Plus3 domain-containing protein. (610 aa)
	A0A1V1T878	Uncharacterized protein. (1121 aa)
	A0A1V1T7Q5	Uncharacterized protein. (1602 aa)
	A0A1V1T7F1	Uncharacterized protein. (305 aa)
	A0A1V1T5W0	FACT complex subunit SPT16. (1031 aa)
	A0A1V1T5R9	Uncharacterized protein. (2862 aa)
	A0A1V1T5N8	Zn(2)-C6 fungal-type domain-containing protein. (784 aa)
	A0A1V1T5A9	CBFD_NFYB_HMF domain-containing protein. (200 aa)
	A0A1V1T4L1	BHLH domain-containing protein. (502 aa)
	A0A1V1T4D4	Zn(2)-C6 fungal-type domain-containing protein. (460 aa)
	A0A1V1T467	CBFD_NFYB_HMF domain-containing protein. (141 aa)
	A0A1V1T449	Abhydrolase_3 domain-containing protein. (337 aa)
	A0A1V1T3M2	Uncharacterized protein. (839 aa)
	A0A1V1T350	TPR_REGION domain-containing protein. (863 aa)
	A0A1V1T308	BZIP domain-containing protein. (578 aa)
	A0A1V1T300	F-box domain-containing protein. (529 aa)
	A0A1V1T2P6	Uncharacterized protein. (1771 aa)
	A0A1V1T2H0	BZIP domain-containing protein. (263 aa)
	A0A1V1T1T8	Uncharacterized protein. (183 aa)
	A0A1V1T1R5	Zn(2)-C6 fungal-type domain-containing protein. (940 aa)
	A0A1V1T1R0	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (735 aa)
	A0A1V1T1L3	Uncharacterized protein. (122 aa)
	A0A1V1T0X2	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (496 aa)
	A0A1V1T0M0	NDT80 domain-containing protein. (560 aa)
	A0A1V1T0A6	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (1155 aa)
	A0A1V1SZG6	NDT80 domain-containing protein. (526 aa)
	A0A1V1SZ59	Uncharacterized protein. (347 aa)
	A0A1V1SZ42	BZIP domain-containing protein. (454 aa)
	A0A1V1SWY5	Uncharacterized protein. (310 aa)
	A0A1V1SWK0	PC4 domain-containing protein. (160 aa)
	A0A1V1SWF3	Uncharacterized protein. (357 aa)
	A0A1V1SWD6	Uncharacterized protein. (272 aa)
	A0A1V1SVN3	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (410 aa)
	A0A1V1SVL4	Uncharacterized protein. (370 aa)
	A0A1V1SUW9	BRCT domain-containing protein. (1107 aa)
	A0A1V1SUJ9	PHD domain-containing protein. (805 aa)
	A0A1V1SUI4	HMG box domain-containing protein. (655 aa)
	A0A1V1SUG5	Uncharacterized protein. (873 aa)
	A0A1V1SU74	F-box domain-containing protein. (493 aa)
	A0A1V1STT2	Hist_deacetyl domain-containing protein. (1182 aa)
	A0A1V1STE2	MADS-box domain-containing protein. (612 aa)
	A0A1V1SRW2	Uncharacterized protein. (487 aa)
	A0A1V1TN84	Uncharacterized protein. (662 aa)
	A0A1V1TNA8	Uncharacterized protein. (366 aa)
	A0A1V1TNM4	Uncharacterized protein. (1409 aa)
	A0A1V1TNS2	CP2 domain-containing protein. (800 aa)
	A0A1V1TNV7	Zn(2)-C6 fungal-type domain-containing protein. (704 aa)
	A0A1V1TP54	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (113 aa)
	A0A1V1TRC3	Zn(2)-C6 fungal-type domain-containing protein. (847 aa)
	A0A1V1TRE0	Uncharacterized protein. (877 aa)
	A0A1V1TRE5	MADS-box domain-containing protein. (220 aa)
	A0A1V1TRY3	Zn(2)-C6 fungal-type domain-containing protein. (452 aa)
	A0A1V1TSN0	Uncharacterized protein. (2868 aa)
	A0A1V1TSN1	Amidohydro-rel domain-containing protein. (313 aa)
	A0A1V1TT09	Zn(2)-C6 fungal-type domain-containing protein. (1102 aa)
	A0A1V1TTM6	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (672 aa)
	A0A1V1TTV0	Uncharacterized protein. (1607 aa)
	A0A1V1TUC3	Response regulatory domain-containing protein. (621 aa)
	A0A1V1TVR7	BZIP domain-containing protein. (401 aa)
	A0A1V1TW14	GATA-type domain-containing protein. (956 aa)
	A0A1V1SRP4	CBFD_NFYB_HMF domain-containing protein. (276 aa)
	A0A1V1SRN4	CBFD_NFYB_HMF domain-containing protein. (399 aa)
	A0A1V1SQT7	Zn(2)-C6 fungal-type domain-containing protein. (839 aa)
	A0A1V1SQH1	CDC73_C domain-containing protein. (417 aa)

Your Current Organism:

fungal sp. No14919

NCBI taxonomy Id: 1813822
Other names: f. sp. No.14919, fungal sp. No.14919

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A1V1SQH1	A0A1V1STT2	CDC73_C domain-containing protein.	Hist_deacetyl domain-containing protein.	0.587
A0A1V1SQH1	A0A1V1T1R0	CDC73_C domain-containing protein.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.601
A0A1V1SQH1	A0A1V1T350	CDC73_C domain-containing protein.	TPR_REGION domain-containing protein.	0.649
A0A1V1SQH1	A0A1V1T5W0	CDC73_C domain-containing protein.	FACT complex subunit SPT16.	0.996
A0A1V1SQH1	A0A1V1T878	CDC73_C domain-containing protein.	Uncharacterized protein.	0.448
A0A1V1SQH1	A0A1V1T8M8	CDC73_C domain-containing protein.	Plus3 domain-containing protein.	0.995
A0A1V1SQH1	A0A1V1TIK3	CDC73_C domain-containing protein.	Uncharacterized protein.	0.999
A0A1V1SQH1	A0A1V1TJD5	CDC73_C domain-containing protein.	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family.	0.962
A0A1V1SQH1	A0A1V1TTM6	CDC73_C domain-containing protein.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.468
A0A1V1SRN4	A0A1V1T467	CBFD_NFYB_HMF domain-containing protein.	CBFD_NFYB_HMF domain-containing protein.	0.990
A0A1V1SRN4	A0A1V1T5A9	CBFD_NFYB_HMF domain-containing protein.	CBFD_NFYB_HMF domain-containing protein.	0.588
A0A1V1SRN4	A0A1V1TLV4	CBFD_NFYB_HMF domain-containing protein.	Fork-head domain-containing protein.	0.423
A0A1V1SRN4	A0A1V1TN84	CBFD_NFYB_HMF domain-containing protein.	Uncharacterized protein.	0.428
A0A1V1SRN4	A0A1V1TNV7	CBFD_NFYB_HMF domain-containing protein.	Zn(2)-C6 fungal-type domain-containing protein.	0.935
A0A1V1SRP4	A0A1V1T467	CBFD_NFYB_HMF domain-containing protein.	CBFD_NFYB_HMF domain-containing protein.	0.468
A0A1V1SRP4	A0A1V1T5A9	CBFD_NFYB_HMF domain-containing protein.	CBFD_NFYB_HMF domain-containing protein.	0.998
A0A1V1SRP4	A0A1V1T878	CBFD_NFYB_HMF domain-containing protein.	Uncharacterized protein.	0.634
A0A1V1SRP4	A0A1V1TDD3	CBFD_NFYB_HMF domain-containing protein.	Uncharacterized protein.	0.708
A0A1V1SRP4	A0A1V1TL24	CBFD_NFYB_HMF domain-containing protein.	GATA-type domain-containing protein.	0.471
A0A1V1SRP4	A0A1V1TNV7	CBFD_NFYB_HMF domain-containing protein.	Zn(2)-C6 fungal-type domain-containing protein.	0.423