(34 nodes) NADP binding network (fungal sp. No14919)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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experimentally determined

Predicted Interactions

gene neighborhood

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Your Input:
	A0A1V1TL70	Uncharacterized protein. (574 aa)
	A0A1V1SQ61	NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (693 aa)
	A0A1V1SRK2	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (219 aa)
	A0A1V1SSJ5	Uncharacterized protein. (226 aa)
	A0A1V1STV6	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (492 aa)
	TAH18	NADPH-dependent diflavin oxidoreductase 1; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe-S cluster of DRE2. Positively controls H(2)O(2)-induced cell death; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (723 aa)
	A0A1V1SUK6	Oxidored_FMN domain-containing protein. (429 aa)
	A0A1V1SUT8	Uncharacterized protein. (516 aa)
	A0A1V1SV50	Uncharacterized protein. (598 aa)
	A0A1V1SVC3	NmrA domain-containing protein. (466 aa)
	A0A1V1SVR3	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (482 aa)
	A0A1V1SX09	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (470 aa)
	A0A1V1T0L4	Uncharacterized protein. (318 aa)
	A0A1V1T0P1	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (333 aa)
	A0A1V1T2G7	Glyceraldehyde-3-phosphate dehydrogenase. (337 aa)
	A0A1V1T4B1	Semialdhyde_dh domain-containing protein. (362 aa)
	A0A1V1T6N5	Uncharacterized protein. (638 aa)
	A0A1V1T7X8	Uncharacterized protein; Belongs to the FMO family. (572 aa)
	A0A1V1TB45	PKS_ER domain-containing protein. (332 aa)
	A0A1V1TD51	Uncharacterized protein. (601 aa)
	A0A1V1TEW1	Uncharacterized protein. (332 aa)
	A0A1V1TF75	PKS_ER domain-containing protein. (390 aa)
	A0A1V1TH45	Glyceraldehyde-3-phosphate dehydrogenase. (339 aa)
	A0A1V1TH72	RibD_C domain-containing protein. (291 aa)
	A0A1V1TIQ2	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (503 aa)
	A0A1V1TIT0	Oxidored_FMN domain-containing protein. (415 aa)
	A0A1V1TJ69	Uncharacterized protein. (625 aa)
	A0A1V1TJS5	Aldedh domain-containing protein. (449 aa)
	A0A1V1TKF2	NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450. (703 aa)
	A0A1V1TL46	Uncharacterized protein; Belongs to the FMO family. (782 aa)
	A0A1V1TLV3	Uncharacterized protein. (595 aa)
	A0A1V1TMC6	Homoserine dehydrogenase. (365 aa)
	A0A1V1TNE8	Uncharacterized protein. (81 aa)
	A0A1V1TTR0	Uncharacterized protein; Belongs to the FMO family. (505 aa)

Your Current Organism:

fungal sp. No14919

NCBI taxonomy Id: 1813822
Other names: f. sp. No.14919, fungal sp. No.14919

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A1V1SRK2	A0A1V1SX09	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	0.698
A0A1V1SRK2	A0A1V1TMC6	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	Homoserine dehydrogenase.	0.533
A0A1V1STV6	A0A1V1SX09	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	0.515
A0A1V1STV6	A0A1V1T2G7	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.	Glyceraldehyde-3-phosphate dehydrogenase.	0.502
A0A1V1STV6	A0A1V1TH45	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.	Glyceraldehyde-3-phosphate dehydrogenase.	0.502
A0A1V1STV6	A0A1V1TH72	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.	RibD_C domain-containing protein.	0.430
A0A1V1STV6	A0A1V1TIQ2	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.	0.997
A0A1V1SUK6	A0A1V1SX09	Oxidored_FMN domain-containing protein.	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	0.467
A0A1V1SUK6	A0A1V1TB45	Oxidored_FMN domain-containing protein.	PKS_ER domain-containing protein.	0.451
A0A1V1SVR3	A0A1V1SX09	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	0.515
A0A1V1SVR3	A0A1V1T2G7	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.	Glyceraldehyde-3-phosphate dehydrogenase.	0.502
A0A1V1SVR3	A0A1V1TH45	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.	Glyceraldehyde-3-phosphate dehydrogenase.	0.502
A0A1V1SVR3	A0A1V1TH72	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.	RibD_C domain-containing protein.	0.430
A0A1V1SVR3	A0A1V1TIQ2	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.	0.988
A0A1V1SX09	A0A1V1SRK2	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	0.698
A0A1V1SX09	A0A1V1STV6	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.	0.515
A0A1V1SX09	A0A1V1SUK6	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	Oxidored_FMN domain-containing protein.	0.467
A0A1V1SX09	A0A1V1SVR3	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.	0.515
A0A1V1SX09	A0A1V1T2G7	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	Glyceraldehyde-3-phosphate dehydrogenase.	0.463
A0A1V1SX09	A0A1V1TH45	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	Glyceraldehyde-3-phosphate dehydrogenase.	0.463