(35 nodes) One carbon pool by folate network (fungal sp. No14919)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	A0A1V1T6Z1	FSH1 domain-containing protein. (266 aa)
	A0A1V1T895	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (687 aa)
	A0A1V1T8C3	PNPLA domain-containing protein. (522 aa)
	A0A1V1T8J0	Uncharacterized protein. (1123 aa)
	A0A1V1TCK1	FSH1 domain-containing protein. (239 aa)
	A0A1V1TD20	Uncharacterized protein. (199 aa)
	A0A1V1TDH3	ACT domain-containing protein. (284 aa)
	A0A1V1TFX2	FSH1 domain-containing protein. (213 aa)
	A0A1V1TG39	Formyl_trans_N domain-containing protein. (462 aa)
	A0A1V1TH00	Thymidylat_synt domain-containing protein. (339 aa)
	A0A1V1TH94	FSH1 domain-containing protein. (235 aa)
	A0A1V1TJ44	PNPLA domain-containing protein. (1184 aa)
	A0A1V1TJ54	PNPLA domain-containing protein. (468 aa)
	A0A1V1TKT0	FSH1 domain-containing protein. (243 aa)
	A0A1V1TPQ0	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. (477 aa)
	A0A1V1TQ65	MGS domain-containing protein. (591 aa)
	A0A1V1TR96	PNPLA domain-containing protein. (1453 aa)
	A0A1V1TTN4	PNPLA domain-containing protein. (630 aa)
	A0A1V1TUE9	FSH1 domain-containing protein. (280 aa)
	A0A1V1TVM3	FSH1 domain-containing protein. (201 aa)
	A0A1V1TUK3	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (479 aa)
	A0A1V1SRK2	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (219 aa)
	A0A1V1STR4	SHMT domain-containing protein. (447 aa)
	A0A1V1STW0	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (616 aa)
	A0A1V1SU47	Queuine tRNA-ribosyltransferase catalytic subunit 1; Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, formi [...] (416 aa)
	A0A1V1SUQ6	Uncharacterized protein. (340 aa)
	A0A1V1SUU8	Uncharacterized protein. (409 aa)
	A0A1V1SV15	FSH1 domain-containing protein. (158 aa)
	A0A1V1SV87	Uncharacterized protein. (256 aa)
	A0A1V1SVD3	Uncharacterized protein. (996 aa)
	A0A1V1SW57	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (517 aa)
	A0A1V1SXW5	FSH1 domain-containing protein. (268 aa)
	A0A1V1T115	Formyl_trans_N domain-containing protein. (227 aa)
	A0A1V1T527	FSH1 domain-containing protein. (299 aa)
	A0A1V1T6M0	Uncharacterized protein. (260 aa)

Your Current Organism:

fungal sp. No14919

NCBI taxonomy Id: 1813822
Other names: f. sp. No.14919, fungal sp. No.14919

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A1V1SRK2	A0A1V1STR4	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	SHMT domain-containing protein.	0.844
A0A1V1SRK2	A0A1V1STW0	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	0.730
A0A1V1SRK2	A0A1V1SU47	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	Queuine tRNA-ribosyltransferase catalytic subunit 1; Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, formi [...]	0.628
A0A1V1SRK2	A0A1V1SUQ6	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	Uncharacterized protein.	0.856
A0A1V1SRK2	A0A1V1SW57	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.844
A0A1V1SRK2	A0A1V1T115	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	Formyl_trans_N domain-containing protein.	0.823
A0A1V1SRK2	A0A1V1T6M0	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	Uncharacterized protein.	0.420
A0A1V1SRK2	A0A1V1T895	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	0.730
A0A1V1SRK2	A0A1V1T8J0	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	Uncharacterized protein.	0.892
A0A1V1SRK2	A0A1V1TDH3	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	ACT domain-containing protein.	0.823
A0A1V1SRK2	A0A1V1TG39	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	Formyl_trans_N domain-containing protein.	0.871
A0A1V1SRK2	A0A1V1TH00	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	Thymidylat_synt domain-containing protein.	0.993
A0A1V1SRK2	A0A1V1TPQ0	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	0.811
A0A1V1SRK2	A0A1V1TQ65	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	MGS domain-containing protein.	0.833
A0A1V1SRK2	A0A1V1TUE9	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	FSH1 domain-containing protein.	0.770
A0A1V1SRK2	A0A1V1TUK3	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.844
A0A1V1STR4	A0A1V1SRK2	SHMT domain-containing protein.	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	0.844
A0A1V1STR4	A0A1V1STW0	SHMT domain-containing protein.	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	0.811
A0A1V1STR4	A0A1V1SU47	SHMT domain-containing protein.	Queuine tRNA-ribosyltransferase catalytic subunit 1; Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, formi [...]	0.566
A0A1V1STR4	A0A1V1SUQ6	SHMT domain-containing protein.	Uncharacterized protein.	0.934