(35 nodes) Mixed, incl. Mediator complex, and AMP-binding enzyme C-terminal domain network (Panaeolus cyanescens)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MED6	Mediator of RNA polymerase II transcription subunit 6; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (292 aa)
	MED4	Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (235 aa)
	CVT24_005749	Uncharacterized protein. (715 aa)
	CVT24_005135	TSPc domain-containing protein. (681 aa)
	CVT24_005153	Uncharacterized protein. (314 aa)
	CVT24_010355	Zn(2)-C6 fungal-type domain-containing protein. (1009 aa)
	CVT24_008879	Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (461 aa)
	CVT24_008209	Uncharacterized protein. (612 aa)
	CVT24_012004	Mediator of RNA polymerase II transcription subunit 7; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. (265 aa)
	CVT24_007305	Uncharacterized protein. (634 aa)
	CVT24_006911	CYCLIN domain-containing protein; Belongs to the cyclin family. (462 aa)
	CVT24_008697	Uncharacterized protein. (655 aa)
	CVT24_002848	Uncharacterized protein. (314 aa)
	CVT24_001670	Uncharacterized protein. (572 aa)
	CVT24_003207	Uncharacterized protein. (954 aa)
	MED10	Mediator of RNA polymerase II transcription subunit 10; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (171 aa)
	CVT24_013135	Uncharacterized protein; Belongs to the cytochrome P450 family. (539 aa)
	CVT24_001052	START domain-containing protein. (2098 aa)
	CVT24_010011	Uncharacterized protein. (171 aa)
	CVT24_008585	Uncharacterized protein. (578 aa)
	CVT24_007536	Protein kinase domain-containing protein. (471 aa)
	CVT24_010278	Uncharacterized protein; Belongs to the cytochrome P450 family. (547 aa)
	CVT24_009816	Uncharacterized protein; Belongs to the cytochrome P450 family. (522 aa)
	CVT24_004115	Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (116 aa)
	CVT24_004119	Med12 domain-containing protein. (1606 aa)
	CVT24_004100	Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1120 aa)
	MED17	Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (511 aa)
	CVT24_003949	Uncharacterized protein. (1137 aa)
	CVT24_003590	Uncharacterized protein. (251 aa)
	CVT24_005196	Uncharacterized protein. (1165 aa)
	CVT24_005078	TSPc domain-containing protein. (682 aa)
	CVT24_011119	TSPc domain-containing protein. (657 aa)
	CVT24_012436	Uncharacterized protein. (582 aa)
	CVT24_012389	Uncharacterized protein; Belongs to the cytochrome P450 family. (562 aa)
	CVT24_008092	Uncharacterized protein. (515 aa)

Your Current Organism:

Panaeolus cyanescens

NCBI taxonomy Id: 181874
Other names: Copelandia cyanescens, P. cyanescens

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CVT24_001052	CVT24_001670	A0A409VX57	A0A409VSR2	START domain-containing protein.	Uncharacterized protein.	0.621
CVT24_001052	CVT24_002848	A0A409VX57	A0A409VN12	START domain-containing protein.	Uncharacterized protein.	0.607
CVT24_001052	CVT24_003207	A0A409VX57	A0A409VUE5	START domain-containing protein.	Uncharacterized protein.	0.773
CVT24_001052	CVT24_003590	A0A409VX57	A0A409Y7P1	START domain-containing protein.	Uncharacterized protein.	0.875
CVT24_001052	CVT24_003949	A0A409VX57	A0A409Y6F4	START domain-containing protein.	Uncharacterized protein.	0.621
CVT24_001052	CVT24_004100	A0A409VX57	A0A409Y649	START domain-containing protein.	Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.968
CVT24_001052	CVT24_004115	A0A409VX57	A0A409Y5Y5	START domain-containing protein.	Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.950
CVT24_001052	CVT24_004119	A0A409VX57	A0A409Y603	START domain-containing protein.	Med12 domain-containing protein.	0.934
CVT24_001052	CVT24_005078	A0A409VX57	A0A409YB07	START domain-containing protein.	TSPc domain-containing protein.	0.625
CVT24_001052	CVT24_005135	A0A409VX57	A0A409V9R0	START domain-containing protein.	TSPc domain-containing protein.	0.625
CVT24_001052	CVT24_005153	A0A409VX57	A0A409V9R5	START domain-containing protein.	Uncharacterized protein.	0.773
CVT24_001052	CVT24_005196	A0A409VX57	A0A409Y9F9	START domain-containing protein.	Uncharacterized protein.	0.773
CVT24_001052	CVT24_005749	A0A409VX57	A0A409V967	START domain-containing protein.	Uncharacterized protein.	0.773
CVT24_001052	CVT24_006911	A0A409VX57	A0A409VK29	START domain-containing protein.	CYCLIN domain-containing protein; Belongs to the cyclin family.	0.972
CVT24_001052	CVT24_007305	A0A409VX57	A0A409VJ77	START domain-containing protein.	Uncharacterized protein.	0.621
CVT24_001052	CVT24_008092	A0A409VX57	A0A409YLJ0	START domain-containing protein.	Uncharacterized protein.	0.773
CVT24_001052	CVT24_008209	A0A409VX57	A0A409VF20	START domain-containing protein.	Uncharacterized protein.	0.621
CVT24_001052	CVT24_008585	A0A409VX57	A0A409W4H4	START domain-containing protein.	Uncharacterized protein.	0.621
CVT24_001052	CVT24_008697	A0A409VX57	A0A409VKM7	START domain-containing protein.	Uncharacterized protein.	0.625
CVT24_001052	CVT24_008879	A0A409VX57	A0A409VAW9	START domain-containing protein.	Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.930