(112 nodes) Ubiquinol biosynthesis, and Phase I - Functionalization of compounds network (Panaeolus cyanescens)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CVT24_006104	Uncharacterized protein. (85 aa)
	CVT24_005823	Uncharacterized protein. (1128 aa)
	CVT24_005128	Abhydrolase_3 domain-containing protein. (410 aa)
	CVT24_004869	Uncharacterized protein. (183 aa)
	CVT24_009504	Uncharacterized protein. (119 aa)
	CVT24_010310	Glyco_hydro_cc domain-containing protein. (1214 aa)
	CVT24_006189	FAD_binding_3 domain-containing protein. (424 aa)
	CVT24_008803	AB hydrolase-1 domain-containing protein. (299 aa)
	CVT24_008421	Uncharacterized protein. (598 aa)
	CVT24_008473	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (504 aa)
	CVT24_007857	Uncharacterized protein. (254 aa)
	CVT24_005775	FAA_hydrolase domain-containing protein. (288 aa)
	CVT24_004254	Uncharacterized protein. (229 aa)
	CVT24_004327	Uncharacterized protein. (554 aa)
	CVT24_008613	Uncharacterized protein. (378 aa)
	CVT24_004767	Uncharacterized protein. (228 aa)
	COQ4	Ubiquinone biosynthesis protein COQ4, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family. (305 aa)
	CVT24_008154	FAD_binding_3 domain-containing protein. (439 aa)
	CVT24_003027	Abhydrolase_3 domain-containing protein. (358 aa)
	CVT24_010797	Uncharacterized protein. (80 aa)
	CVT24_010827	MBOAT_2 domain-containing protein. (395 aa)
	CVT24_012113	FAD_binding_3 domain-containing protein. (555 aa)
	CVT24_000331	Uncharacterized protein. (247 aa)
	CVT24_007221	Uncharacterized protein. (526 aa)
	CVT24_007120	FAD_binding_3 domain-containing protein. (565 aa)
	CVT24_003159	Ubiquinone biosynthesis protein; Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. (232 aa)
	CVT24_002943	Uncharacterized protein. (371 aa)
	CVT24_004805	Lactamase_B domain-containing protein. (299 aa)
	CVT24_004791	Uncharacterized protein. (1567 aa)
	CVT24_000352	Uncharacterized protein. (301 aa)
	CVT24_001474	Uncharacterized protein. (608 aa)
	COQ6	Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. (758 aa)
	CVT24_001204	AB hydrolase-1 domain-containing protein. (342 aa)
	CVT24_006436	Pyr_redox_2 domain-containing protein. (594 aa)
	CVT24_002347	Uncharacterized protein. (837 aa)
	CVT24_004543	Uncharacterized protein. (420 aa)
	CVT24_002064	BZIP domain-containing protein. (454 aa)
	COQ7	5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. (257 aa)
	CVT24_004888	Uncharacterized protein. (663 aa)
	CVT24_007959	Uncharacterized protein; Belongs to the FMO family. (1591 aa)
	CVT24_012250	Uncharacterized protein. (870 aa)
	CVT24_000691	Uncharacterized protein. (414 aa)
	CVT24_000688	Uncharacterized protein. (309 aa)
	CVT24_004191	Uncharacterized protein. (660 aa)
	CVT24_003825	Uncharacterized protein. (923 aa)
	CVT24_003050	Uncharacterized protein. (431 aa)
	CVT24_003052	Uncharacterized protein. (231 aa)
	CVT24_010065	FAD_binding_3 domain-containing protein. (577 aa)
	CVT24_010175	Uncharacterized protein. (647 aa)
	CVT24_010117	FAD_binding_3 domain-containing protein. (578 aa)
	CVT24_010927	Uncharacterized protein. (962 aa)
	CVT24_006553	Uncharacterized protein. (640 aa)
	CVT24_003653	Uncharacterized protein. (282 aa)
	CVT24_002655	Uncharacterized protein. (586 aa)
	CVT24_012549	Uncharacterized protein. (787 aa)
	CVT24_011971	AB hydrolase-1 domain-containing protein. (394 aa)
	CVT24_008321	Abhydrolase_3 domain-containing protein. (330 aa)
	CVT24_004089	Uncharacterized protein. (211 aa)
	CVT24_003984	Uncharacterized protein. (538 aa)
	CVT24_003393	Uncharacterized protein. (625 aa)
	CVT24_009265	Uncharacterized protein; Belongs to the FMO family. (1183 aa)
	CVT24_009158	Abhydrolase_3 domain-containing protein. (371 aa)
	CVT24_005244	EHN domain-containing protein. (708 aa)
	CVT24_005335	Uncharacterized protein. (1294 aa)
	CVT24_009000	TauD domain-containing protein. (385 aa)
	CVT24_008962	FAD_binding_3 domain-containing protein. (506 aa)
	CVT24_004953	Abhydrolase_3 domain-containing protein. (287 aa)
	CVT24_004906	Methyltransf_25 domain-containing protein. (267 aa)
	CVT24_005032	BTB domain-containing protein. (633 aa)
	CVT24_004590	Abhydrolase_3 domain-containing protein. (362 aa)
	CVT24_005507	Uncharacterized protein. (1379 aa)
	CVT24_001000	Uncharacterized protein. (246 aa)
	CVT24_000321	Uncharacterized protein; Belongs to the FMO family. (668 aa)
	CVT24_000379	MBOAT_2 domain-containing protein. (437 aa)
	CVT24_000373	Proline iminopeptidase; Belongs to the peptidase S33 family. (313 aa)
	CVT24_001856	ABC1 domain-containing protein. (672 aa)
	CVT24_001599	Abhydrolase_3 domain-containing protein. (349 aa)
	CVT24_001301	Aldolase_II domain-containing protein. (310 aa)
	CVT24_011107	MBOAT_2 domain-containing protein. (406 aa)
	CVT24_011218	EHN domain-containing protein. (425 aa)
	CVT24_011393	AB hydrolase-1 domain-containing protein. (414 aa)
	CVT24_011462	Uncharacterized protein. (470 aa)
	CVT24_001955	ABC1 domain-containing protein. (638 aa)
	CVT24_012200	Uncharacterized protein. (326 aa)
	CVT24_012202	Uncharacterized protein. (231 aa)
	CVT24_012201	Uncharacterized protein. (326 aa)
	CVT24_012399	Uncharacterized protein. (76 aa)
	CVT24_012818	Uncharacterized protein. (507 aa)
	CVT24_012507	Beta-lactamase domain-containing protein. (413 aa)
	CVT24_007765	Uncharacterized protein; Belongs to the FMO family. (572 aa)
	CVT24_007744	Uncharacterized protein. (531 aa)
	CVT24_007754	Uncharacterized protein. (566 aa)
	CVT24_007372	Uncharacterized protein. (565 aa)
	CVT24_011861	Uncharacterized protein. (576 aa)
	CVT24_011851	Uncharacterized protein. (163 aa)
	CVT24_011826	Uncharacterized protein. (819 aa)
	CVT24_007145	Uncharacterized protein. (251 aa)
	CVT24_007146	EthD domain-containing protein. (238 aa)
	CVT24_007147	EthD domain-containing protein. (226 aa)
	CVT24_007994	EHN domain-containing protein. (402 aa)
	CVT24_008025	EHN domain-containing protein. (360 aa)
	CVT24_008033	Uncharacterized protein. (274 aa)
	CVT24_006624	EHN domain-containing protein. (406 aa)
	CVT24_004216	Uncharacterized protein. (881 aa)
	CVT24_013028	Uncharacterized protein. (620 aa)
	CVT24_004167	Uncharacterized protein. (324 aa)
	CVT24_005623	FAD_binding_3 domain-containing protein. (479 aa)
	CVT24_002996	Uncharacterized protein. (410 aa)
	CVT24_000827	MBOAT_2 domain-containing protein. (379 aa)
	CVT24_002694	Uncharacterized protein. (573 aa)
	CVT24_002688	Alpha-type protein kinase domain-containing protein. (496 aa)
	CVT24_002695	Uncharacterized protein. (574 aa)

Your Current Organism:

Panaeolus cyanescens

NCBI taxonomy Id: 181874
Other names: Copelandia cyanescens, P. cyanescens

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
COQ4	COQ6	A0A409VEQ7	A0A409VT70	Ubiquinone biosynthesis protein COQ4, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family.	Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.	0.694
COQ4	COQ7	A0A409VEQ7	A0A409W1T8	Ubiquinone biosynthesis protein COQ4, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family.	5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides.	0.615
COQ4	CVT24_000688	A0A409VEQ7	A0A409W729	Ubiquinone biosynthesis protein COQ4, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family.	Uncharacterized protein.	0.677
COQ4	CVT24_001955	A0A409VEQ7	A0A409YHM9	Ubiquinone biosynthesis protein COQ4, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family.	ABC1 domain-containing protein.	0.611
COQ4	CVT24_003159	A0A409VEQ7	A0A409VP30	Ubiquinone biosynthesis protein COQ4, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family.	Ubiquinone biosynthesis protein; Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.	0.780
COQ4	CVT24_004767	A0A409VEQ7	A0A409VEH8	Ubiquinone biosynthesis protein COQ4, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family.	Uncharacterized protein.	0.556
COQ4	CVT24_004906	A0A409VEQ7	A0A409YB33	Ubiquinone biosynthesis protein COQ4, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family.	Methyltransf_25 domain-containing protein.	0.556
COQ4	CVT24_007857	A0A409VEQ7	A0A409VCF2	Ubiquinone biosynthesis protein COQ4, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family.	Uncharacterized protein.	0.677
COQ4	CVT24_008033	A0A409VEQ7	A0A409YR05	Ubiquinone biosynthesis protein COQ4, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family.	Uncharacterized protein.	0.556
COQ4	CVT24_009504	A0A409VEQ7	A0A409VAH8	Ubiquinone biosynthesis protein COQ4, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family.	Uncharacterized protein.	0.471
COQ6	COQ4	A0A409VT70	A0A409VEQ7	Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.	Ubiquinone biosynthesis protein COQ4, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family.	0.694
COQ6	COQ7	A0A409VT70	A0A409W1T8	Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.	5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides.	0.908
COQ6	CVT24_000331	A0A409VT70	A0A409VIV8	Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.	Uncharacterized protein.	0.530
COQ6	CVT24_000688	A0A409VT70	A0A409W729	Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.	Uncharacterized protein.	0.938
COQ6	CVT24_001955	A0A409VT70	A0A409YHM9	Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.	ABC1 domain-containing protein.	0.725
COQ6	CVT24_003159	A0A409VT70	A0A409VP30	Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.	Ubiquinone biosynthesis protein; Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.	0.797
COQ6	CVT24_004767	A0A409VT70	A0A409VEH8	Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.	Uncharacterized protein.	0.596
COQ6	CVT24_004906	A0A409VT70	A0A409YB33	Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.	Methyltransf_25 domain-containing protein.	0.596
COQ6	CVT24_007857	A0A409VT70	A0A409VCF2	Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.	Uncharacterized protein.	0.953
COQ6	CVT24_008033	A0A409VT70	A0A409YR05	Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.	Uncharacterized protein.	0.596