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CVT24_000437 CVT24_000437 CVT24_000455 CVT24_000455 CVT24_005977 CVT24_005977 CVT24_005972 CVT24_005972 CVT24_005980 CVT24_005980 CVT24_005943 CVT24_005943 CVT24_004752 CVT24_004752 CVT24_000503 CVT24_000503 CVT24_009422 CVT24_009422 CVT24_008361 CVT24_008361 CVT24_005971 CVT24_005971 CVT24_005795 CVT24_005795 CVT24_008868 CVT24_008868 CVT24_008922 CVT24_008922 CVT24_004930 CVT24_004930 CVT24_005973 CVT24_005973 CVT24_011210 CVT24_011210 CVT24_006909 CVT24_006909 CVT24_008821 CVT24_008821 CVT24_011540 CVT24_011540 CVT24_011513 CVT24_011513 CVT24_004844 CVT24_004844 CVT24_007578 CVT24_007578 CVT24_003872 CVT24_003872 CVT24_000856 CVT24_000856 CVT24_011962 CVT24_011962 CVT24_007837 CVT24_007837 CVT24_008077 CVT24_008077 CVT24_012894 CVT24_012894 CVT24_001491 CVT24_001491 CVT24_000195 CVT24_000195 CVT24_003788 CVT24_003788 CVT24_001936 CVT24_001936 CVT24_002658 CVT24_002658 CVT24_006857 CVT24_006857 CVT24_007783 CVT24_007783 CVT24_003850 CVT24_003850 CVT24_000675 CVT24_000675 CVT24_005436 CVT24_005436 CVT24_007539 CVT24_007539 CVT24_004060 CVT24_004060 CVT24_004102 CVT24_004102 CVT24_004043 CVT24_004043 CVT24_003989 CVT24_003989 CVT24_004034 CVT24_004034 CVT24_003314 CVT24_003314 CVT24_003356 CVT24_003356 CVT24_003331 CVT24_003331 CVT24_009336 CVT24_009336 CVT24_009334 CVT24_009334 CVT24_009181 CVT24_009181 CVT24_009715 CVT24_009715 CVT24_009741 CVT24_009741 CVT24_009562 CVT24_009562 CVT24_009571 CVT24_009571 CVT24_009008 CVT24_009008 CVT24_008951 CVT24_008951 CVT24_005528 CVT24_005528 CVT24_005527 CVT24_005527 CVT24_005456 CVT24_005456 CVT24_005492 CVT24_005492 CVT24_000879 CVT24_000879 CVT24_000878 CVT24_000878 CVT24_000959 CVT24_000959 CVT24_000971 CVT24_000971 CVT24_011120 CVT24_011120 CVT24_011134 CVT24_011134 CVT24_002190 CVT24_002190 CVT24_002131 CVT24_002131 CVT24_002125 CVT24_002125 CVT24_002319 CVT24_002319 CVT24_007019 CVT24_007019 CVT24_007371 CVT24_007371 CVT24_010660 CVT24_010660 CVT24_013260 CVT24_013260 CVT24_013123 CVT24_013123 CVT24_007903 CVT24_007903 CVT24_007971 CVT24_007971 CVT24_007978 CVT24_007978 CVT24_008030 CVT24_008030 CVT24_000642 CVT24_000642 CVT24_011571 CVT24_011571 CVT24_010479 CVT24_010479 CVT24_003898 CVT24_003898 CVT24_010537 CVT24_010537 CVT24_012124 CVT24_012124
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
CVT24_000437Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (523 aa)
CVT24_000455Pyruvate kinase; Belongs to the pyruvate kinase family. (537 aa)
CVT24_005977Uncharacterized protein. (343 aa)
CVT24_005972Uncharacterized protein. (501 aa)
CVT24_005980Uncharacterized protein; Belongs to the cytochrome b5 family. (499 aa)
CVT24_005943Citrate synthase; Belongs to the citrate synthase family. (463 aa)
CVT24_004752Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (433 aa)
CVT24_000503Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (406 aa)
CVT24_009422Zn(2)-C6 fungal-type domain-containing protein. (389 aa)
CVT24_0083613-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (381 aa)
CVT24_005971Uncharacterized protein. (344 aa)
CVT24_005795Uncharacterized protein; Belongs to the aldehyde dehydrogenase family. (529 aa)
CVT24_008868Uncharacterized protein. (359 aa)
CVT24_008922Aspartate aminotransferase. (1427 aa)
CVT24_004930Peptidase_M24 domain-containing protein. (448 aa)
CVT24_005973Uncharacterized protein. (777 aa)
CVT24_011210Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1206 aa)
CVT24_006909Malate dehydrogenase. (339 aa)
CVT24_008821DUF1752 domain-containing protein. (1774 aa)
CVT24_011540FAD-binding PCMH-type domain-containing protein. (492 aa)
CVT24_011513Transket_pyr domain-containing protein. (421 aa)
CVT24_004844Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily. (371 aa)
CVT24_007578FAD-binding PCMH-type domain-containing protein. (560 aa)
CVT24_0038723-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (759 aa)
CVT24_000856Beta-glucosidase; Belongs to the glycosyl hydrolase 3 family. (1501 aa)
CVT24_011962Uncharacterized protein; Belongs to the DapA family. (312 aa)
CVT24_007837Isocitrate lyase. (569 aa)
CVT24_008077Uncharacterized protein; Belongs to the cytochrome b5 family. (470 aa)
CVT24_012894Uncharacterized protein; Belongs to the TPP enzyme family. (642 aa)
CVT24_001491Succinate dehydrogenase [ubiquinone] cytochrome b small subunit. (166 aa)
CVT24_000195Dihydrolipoyl dehydrogenase. (502 aa)
CVT24_003788Lipoyl-binding domain-containing protein. (434 aa)
CVT24_001936Citrate synthase; Belongs to the citrate synthase family. (465 aa)
CVT24_002658Uncharacterized protein. (882 aa)
CVT24_006857Acetolactate synthase. (701 aa)
CVT24_007783Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (388 aa)
CVT24_003850Uncharacterized protein. (338 aa)
CVT24_000675Citrate synthase; Belongs to the citrate synthase family. (473 aa)
CVT24_005436Iso_dh domain-containing protein. (361 aa)
CVT24_007539Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (450 aa)
CVT24_004060Cytochrome b5 heme-binding domain-containing protein. (582 aa)
CVT24_004102Uncharacterized protein. (564 aa)
CVT24_004043Iso_dh domain-containing protein. (580 aa)
CVT24_003989Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (374 aa)
CVT24_004034Iso_dh domain-containing protein. (373 aa)
CVT24_003314Malate dehydrogenase. (337 aa)
CVT24_003356Pyruvate carboxyltransferase domain-containing protein. (791 aa)
CVT24_003331Uncharacterized protein. (589 aa)
CVT24_009336Ketol-acid reductoisomerase, mitochondrial; Belongs to the ketol-acid reductoisomerase family. (408 aa)
CVT24_009334Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis. (735 aa)
CVT24_009181Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (438 aa)
CVT24_009715ACT domain-containing protein. (1162 aa)
CVT24_009741Malate synthase; Belongs to the malate synthase family. (541 aa)
CVT24_009562Uncharacterized protein. (276 aa)
CVT24_009571Lipoyl-binding domain-containing protein. (288 aa)
CVT24_009008Uncharacterized protein. (1027 aa)
CVT24_008951FAD-binding PCMH-type domain-containing protein. (759 aa)
CVT24_005528Uncharacterized protein. (294 aa)
CVT24_005527Uncharacterized protein. (266 aa)
CVT24_005456Transket_pyr domain-containing protein. (946 aa)
CVT24_005492Uncharacterized protein. (137 aa)
CVT24_000879Uncharacterized protein. (496 aa)
CVT24_000878Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (428 aa)
CVT24_000959Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (782 aa)
CVT24_000971Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (275 aa)
CVT24_011120Malic enzyme. (543 aa)
CVT24_011134Succinate dehydrogenase assembly factor 2, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer. (160 aa)
CVT24_002190Pyruvate carboxyltransferase domain-containing protein; Belongs to the alpha-IPM synthase/homocitrate synthase family. (566 aa)
CVT24_002131Uncharacterized protein. (610 aa)
CVT24_002125Uncharacterized protein. (856 aa)
CVT24_0023192-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (441 aa)
CVT24_007019Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (1246 aa)
CVT24_007371ATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family. (1155 aa)
CVT24_010660NAD-specific glutamate dehydrogenase; NAD(+)-dependent glutamate dehydrogenase which degrades glutamate to ammonia and alpha-ketoglutarate. Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (1046 aa)
CVT24_013260DAO domain-containing protein. (376 aa)
CVT24_013123Isochorismatase domain-containing protein. (236 aa)
CVT24_007903Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (495 aa)
CVT24_007971Uncharacterized protein; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (821 aa)
CVT24_007978Malic enzyme. (539 aa)
CVT24_008030Zn(2)-C6 fungal-type domain-containing protein. (449 aa)
CVT24_000642Iso_dh domain-containing protein. (439 aa)
CVT24_011571Aspartate aminotransferase. (426 aa)
CVT24_010479Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily. (358 aa)
CVT24_003898Transket_pyr domain-containing protein. (1006 aa)
CVT24_010537FAD-binding PCMH-type domain-containing protein. (543 aa)
CVT24_012124Uncharacterized protein. (549 aa)
Your Current Organism:
Panaeolus cyanescens
NCBI taxonomy Id: 181874
Other names: Copelandia cyanescens, P. cyanescens
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