(7 nodes) Mixed, incl. Mitochondrial tricarboxylic acid cycle enzyme complex, and Lipoic acid binding network (Panaeolus cyanescens)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CVT24_011513	Transket_pyr domain-containing protein. (421 aa)
	CVT24_009571	Lipoyl-binding domain-containing protein. (288 aa)
	CVT24_009008	Uncharacterized protein. (1027 aa)
	CVT24_005456	Transket_pyr domain-containing protein. (946 aa)
	CVT24_002319	2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (441 aa)
	CVT24_013123	Isochorismatase domain-containing protein. (236 aa)
	CVT24_007903	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (495 aa)

Your Current Organism:

Panaeolus cyanescens

NCBI taxonomy Id: 181874
Other names: Copelandia cyanescens, P. cyanescens

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CVT24_002319	CVT24_005456	A0A409YII8	A0A409YC32	2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).	Transket_pyr domain-containing protein.	0.771
CVT24_002319	CVT24_007903	A0A409YII8	A0A409YQJ2	2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.993
CVT24_002319	CVT24_009008	A0A409YII8	A0A409YAM6	2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).	Uncharacterized protein.	0.969
CVT24_002319	CVT24_009571	A0A409YII8	A0A409YAA5	2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).	Lipoyl-binding domain-containing protein.	0.952
CVT24_002319	CVT24_011513	A0A409YII8	A0A409VMK8	2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).	Transket_pyr domain-containing protein.	0.999
CVT24_002319	CVT24_013123	A0A409YII8	A0A409YP70	2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).	Isochorismatase domain-containing protein.	0.953
CVT24_005456	CVT24_002319	A0A409YC32	A0A409YII8	Transket_pyr domain-containing protein.	2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).	0.771
CVT24_005456	CVT24_007903	A0A409YC32	A0A409YQJ2	Transket_pyr domain-containing protein.	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.950
CVT24_005456	CVT24_009008	A0A409YC32	A0A409YAM6	Transket_pyr domain-containing protein.	Uncharacterized protein.	0.938
CVT24_005456	CVT24_009571	A0A409YC32	A0A409YAA5	Transket_pyr domain-containing protein.	Lipoyl-binding domain-containing protein.	0.950
CVT24_005456	CVT24_011513	A0A409YC32	A0A409VMK8	Transket_pyr domain-containing protein.	Transket_pyr domain-containing protein.	0.797
CVT24_005456	CVT24_013123	A0A409YC32	A0A409YP70	Transket_pyr domain-containing protein.	Isochorismatase domain-containing protein.	0.964
CVT24_007903	CVT24_002319	A0A409YQJ2	A0A409YII8	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).	0.993
CVT24_007903	CVT24_005456	A0A409YQJ2	A0A409YC32	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	Transket_pyr domain-containing protein.	0.950
CVT24_007903	CVT24_009008	A0A409YQJ2	A0A409YAM6	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	Uncharacterized protein.	0.939
CVT24_007903	CVT24_009571	A0A409YQJ2	A0A409YAA5	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	Lipoyl-binding domain-containing protein.	0.664
CVT24_007903	CVT24_011513	A0A409YQJ2	A0A409VMK8	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	Transket_pyr domain-containing protein.	0.996
CVT24_007903	CVT24_013123	A0A409YQJ2	A0A409YP70	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	Isochorismatase domain-containing protein.	0.678
CVT24_009008	CVT24_002319	A0A409YAM6	A0A409YII8	Uncharacterized protein.	2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).	0.969
CVT24_009008	CVT24_005456	A0A409YAM6	A0A409YC32	Uncharacterized protein.	Transket_pyr domain-containing protein.	0.938