(72 nodes) Hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds network (Panaeolus cyanescens)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CVT24_001253	Uncharacterized protein. (258 aa)
	CVT24_002021	Uncharacterized protein. (276 aa)
	CVT24_002034	GTP_cyclohydroI domain-containing protein. (284 aa)
	CVT24_012383	A_deaminase domain-containing protein. (820 aa)
	CVT24_007739	CMP/dCMP-type deaminase domain-containing protein. (179 aa)
	CVT24_013108	Amidohydro-rel domain-containing protein. (540 aa)
	CVT24_007151	Uncharacterized protein. (227 aa)
	CVT24_010435	Nt_Gln_amidase domain-containing protein. (196 aa)
	CVT24_010204	Uncharacterized protein. (795 aa)
	CVT24_010335	CMP/dCMP-type deaminase domain-containing protein. (184 aa)
	CVT24_000621	Hist_deacetyl domain-containing protein. (592 aa)
	CVT24_001488	Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. (708 aa)
	CVT24_005597	Hydantoinase_B domain-containing protein. (586 aa)
	CVT24_010834	A_deaminase domain-containing protein. (360 aa)
	CVT24_006300	Uncharacterized protein. (828 aa)
	CVT24_000535	Uncharacterized protein. (1184 aa)
	CVT24_000510	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. (554 aa)
	CVT24_011383	NAAA-beta domain-containing protein. (399 aa)
	CVT24_011060	HTH APSES-type domain-containing protein. (525 aa)
	CVT24_008200	Hist_deacetyl domain-containing protein. (592 aa)
	CVT24_004857	Urease domain-containing protein. (956 aa)
	CVT24_010323	Deacetylase sirtuin-type domain-containing protein. (995 aa)
	CVT24_004264	NodB homology domain-containing protein. (264 aa)
	CVT24_005136	Uncharacterized protein. (658 aa)
	CVT24_009037	Deacetylase sirtuin-type domain-containing protein; Belongs to the RNase T2 family. (874 aa)
	CVT24_009586	Amidohydro-rel domain-containing protein. (351 aa)
	CVT24_009625	Uncharacterized protein. (2228 aa)
	CVT24_005362	Thioredoxin domain-containing protein. (169 aa)
	CVT24_009718	Uncharacterized protein. (366 aa)
	CVT24_003812	NodB homology domain-containing protein. (256 aa)
	CVT24_013132	Uncharacterized protein. (307 aa)
	CVT24_011920	CN hydrolase domain-containing protein. (345 aa)
	CVT24_006455	Deacetylase sirtuin-type domain-containing protein. (273 aa)
	CVT24_007893	CMP/dCMP-type deaminase domain-containing protein. (210 aa)
	CVT24_007454	Neutral ceramidase. (907 aa)
	CVT24_007533	Hist_deacetyl domain-containing protein. (513 aa)
	CVT24_007338	Deacetylase sirtuin-type domain-containing protein. (546 aa)
	CVT24_012624	Uncharacterized protein; Belongs to the arginase family. (432 aa)
	CVT24_003860	NAD-dependent protein deacylase; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. (299 aa)
	CVT24_007938	Uncharacterized protein. (277 aa)
	CVT24_002381	NodB homology domain-containing protein. (272 aa)
	CVT24_008818	NodB homology domain-containing protein. (254 aa)
	CVT24_000331	Uncharacterized protein. (247 aa)
	CVT24_011545	CMP/dCMP-type deaminase domain-containing protein. (155 aa)
	CVT24_004796	NAD-dependent protein deacetylase; Belongs to the sirtuin family. Class I subfamily. (395 aa)
	CVT24_007716	A to I editase domain-containing protein. (405 aa)
	CVT24_006153	Uncharacterized protein. (1162 aa)
	CVT24_005978	Amidohydro-rel domain-containing protein. (510 aa)
	CVT24_006777	Uncharacterized protein. (685 aa)
	CVT24_004913	GTP_cyclohydro2 domain-containing protein. (510 aa)
	CVT24_004744	Hist_deacetyl domain-containing protein. (566 aa)
	CVT24_004454	HIT domain-containing protein. (146 aa)
	CVT24_009425	Amidohydro-rel domain-containing protein. (422 aa)
	CVT24_008896	Uncharacterized protein; Belongs to the arginase family. (407 aa)
	CVT24_008897	NTF2 domain-containing protein. (694 aa)
	CVT24_008918	ANK_REP_REGION domain-containing protein. (680 aa)
	CVT24_005182	Uncharacterized protein. (335 aa)
	CVT24_005241	Uncharacterized protein. (568 aa)
	CVT24_005353	5-hydroxyisourate hydrolase; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. (133 aa)
	CVT24_009241	Uncharacterized protein. (881 aa)
	CVT24_003611	Uncharacterized protein. (125 aa)
	CVT24_003635	Uncharacterized protein. (733 aa)
	CVT24_003385	Uncharacterized protein; Belongs to the arginase family. (331 aa)
	CVT24_004037	NodB homology domain-containing protein. (454 aa)
	CVT24_004017	Histidine biosynthesis trifunctional protein. (845 aa)
	CVT24_000306	Uncharacterized protein. (530 aa)
	CVT24_010531	Uncharacterized protein. (946 aa)
	CVT24_001283	Hist_deacetyl domain-containing protein. (428 aa)
	CVT24_000761	MGS domain-containing protein. (600 aa)
	CVT24_000477	NodB homology domain-containing protein. (749 aa)
	CVT24_009004	Amidohydro-rel domain-containing protein. (1339 aa)
	CVT24_000964	CN hydrolase domain-containing protein. (304 aa)

Your Current Organism:

Panaeolus cyanescens

NCBI taxonomy Id: 181874
Other names: Copelandia cyanescens, P. cyanescens

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CVT24_000306	CVT24_002034	A0A409WSS7	A0A409YHP4	Uncharacterized protein.	GTP_cyclohydroI domain-containing protein.	0.688
CVT24_000306	CVT24_006777	A0A409WSS7	A0A409V9A7	Uncharacterized protein.	Uncharacterized protein.	0.605
CVT24_000306	CVT24_007739	A0A409WSS7	A0A409YKM2	Uncharacterized protein.	CMP/dCMP-type deaminase domain-containing protein.	0.544
CVT24_000306	CVT24_007893	A0A409WSS7	A0A409VZR6	Uncharacterized protein.	CMP/dCMP-type deaminase domain-containing protein.	0.544
CVT24_000306	CVT24_013108	A0A409WSS7	A0A409YNA2	Uncharacterized protein.	Amidohydro-rel domain-containing protein.	0.598
CVT24_000331	CVT24_000964	A0A409VIV8	A0A409YCD9	Uncharacterized protein.	CN hydrolase domain-containing protein.	0.691
CVT24_000331	CVT24_003611	A0A409VIV8	A0A409Y802	Uncharacterized protein.	Uncharacterized protein.	0.691
CVT24_000331	CVT24_011920	A0A409VIV8	A0A409VXR5	Uncharacterized protein.	CN hydrolase domain-containing protein.	0.691
CVT24_000477	CVT24_003385	A0A409V8D1	A0A409Y7B7	NodB homology domain-containing protein.	Uncharacterized protein; Belongs to the arginase family.	0.507
CVT24_000477	CVT24_008896	A0A409V8D1	A0A409VAY1	NodB homology domain-containing protein.	Uncharacterized protein; Belongs to the arginase family.	0.438
CVT24_000477	CVT24_012624	A0A409V8D1	A0A409W6B9	NodB homology domain-containing protein.	Uncharacterized protein; Belongs to the arginase family.	0.438
CVT24_000510	CVT24_000761	A0A409V8E8	A0A409YZ36	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	MGS domain-containing protein.	0.935
CVT24_000510	CVT24_004017	A0A409V8E8	A0A409Y669	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	Histidine biosynthesis trifunctional protein.	0.997
CVT24_000510	CVT24_006153	A0A409V8E8	A0A409V8L7	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	Uncharacterized protein.	0.763
CVT24_000510	CVT24_007151	A0A409V8E8	A0A409YPH7	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	Uncharacterized protein.	0.780
CVT24_000510	CVT24_008918	A0A409V8E8	A0A409VAZ4	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	ANK_REP_REGION domain-containing protein.	0.709
CVT24_000510	CVT24_009625	A0A409V8E8	A0A409YA10	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	Uncharacterized protein.	0.774
CVT24_000621	CVT24_003860	A0A409YTA7	A0A409W883	Hist_deacetyl domain-containing protein.	NAD-dependent protein deacylase; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.	0.420
CVT24_000621	CVT24_004454	A0A409YTA7	A0A409V9X2	Hist_deacetyl domain-containing protein.	HIT domain-containing protein.	0.503
CVT24_000621	CVT24_004744	A0A409YTA7	A0A409V9S8	Hist_deacetyl domain-containing protein.	Hist_deacetyl domain-containing protein.	0.420