(78 nodes) Cellular response to chemical stress network (Panaeolus cyanescens)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

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protein homology

Your Input:
	PIM1	Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family. (1079 aa)
	CVT24_000255	Peroxidase; Belongs to the peroxidase family. Ligninase subfamily. (768 aa)
	CVT24_008719	Protein kinase domain-containing protein. (593 aa)
	CVT24_007303	Uncharacterized protein. (366 aa)
	CVT24_007178	Uncharacterized protein. (296 aa)
	CVT24_000218	PHB domain-containing protein. (363 aa)
	CVT24_010817	Peroxidase; Belongs to the peroxidase family. (380 aa)
	CVT24_008211	Aldo_ket_red domain-containing protein. (308 aa)
	CVT24_004130	PEROXIDASE_4 domain-containing protein. (360 aa)
	CVT24_012642	Peroxidase; Belongs to the peroxidase family. Ligninase subfamily. (358 aa)
	CVT24_008264	Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. (246 aa)
	CVT24_010947	Uncharacterized protein. (434 aa)
	CVT24_011317	Peroxidase; Belongs to the peroxidase family. Ligninase subfamily. (357 aa)
	CVT24_001715	PHB domain-containing protein. (364 aa)
	CVT24_002628	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (204 aa)
	CVT24_001806	Uncharacterized protein. (1456 aa)
	CVT24_006363	PMSR domain-containing protein. (189 aa)
	CVT24_006355	Aldo_ket_red domain-containing protein. (144 aa)
	CVT24_012382	Peroxidase; Belongs to the peroxidase family. Ligninase subfamily. (357 aa)
	CVT24_001953	Peroxidase; Belongs to the peroxidase family. Ligninase subfamily. (354 aa)
	CVT24_011667	Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. (180 aa)
	CVT24_011638	Lon protease homolog; Belongs to the peptidase S16 family. (934 aa)
	CVT24_012716	Uncharacterized protein. (158 aa)
	CVT24_003856	GAF domain-containing protein. (204 aa)
	CVT24_003049	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (157 aa)
	CVT24_002493	Peroxidase; Belongs to the peroxidase family. Ligninase subfamily. (357 aa)
	CVT24_010389	Peroxidase; Belongs to the peroxidase family. Ligninase subfamily. (352 aa)
	CVT24_010231	Uncharacterized protein. (438 aa)
	CVT24_009133	Aldo_ket_red domain-containing protein. (303 aa)
	CVT24_009168	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (214 aa)
	CVT24_005302	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (319 aa)
	CVT24_005317	Mitogen-activated protein kinase. (355 aa)
	CVT24_009008	Uncharacterized protein. (1027 aa)
	CVT24_004899	Uncharacterized protein. (483 aa)
	CVT24_011159	Aldo_ket_red domain-containing protein. (335 aa)
	CVT24_002446	Peroxidase; Belongs to the peroxidase family. Ligninase subfamily. (355 aa)
	CVT24_002895	Uncharacterized protein. (140 aa)
	CVT24_010051	Peroxidase; Belongs to the peroxidase family. Ligninase subfamily. (560 aa)
	CVT24_010939	HPt domain-containing protein. (126 aa)
	CVT24_008342	Thioredoxin domain-containing protein. (222 aa)
	CVT24_004565	Glutaredoxin domain-containing protein. (222 aa)
	CVT24_008423	Uncharacterized protein. (929 aa)
	CVT24_004702	SH3 domain-containing protein; Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity. (633 aa)
	CVT24_006844	PKS_ER domain-containing protein. (438 aa)
	CVT24_006846	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (162 aa)
	CVT24_003275	Uncharacterized protein. (482 aa)
	CVT24_000976	Thioredoxin domain-containing protein. (241 aa)
	CVT24_000963	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (170 aa)
	CVT24_006192	Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. (309 aa)
	CVT24_006280	Sulfhydryl oxidase. (196 aa)
	CVT24_004845	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (490 aa)
	CVT24_005387	Response regulatory domain-containing protein. (1316 aa)
	CVT24_005069	Peroxidase; Belongs to the peroxidase family. Ligninase subfamily. (357 aa)
	CVT24_007715	Sod_Fe_C domain-containing protein. (363 aa)
	CVT24_007668	Uncharacterized protein. (569 aa)
	CVT24_000360	Glutamate decarboxylase; Belongs to the group II decarboxylase family. (533 aa)
	CVT24_006872	Glutaredoxin domain-containing protein. (164 aa)
	CVT24_003811	Uncharacterized protein. (243 aa)
	CVT24_003777	Peroxidase; Belongs to the peroxidase family. Ligninase subfamily. (358 aa)
	CVT24_001207	Uncharacterized protein. (696 aa)
	CVT24_004957	Thioredoxin domain-containing protein. (221 aa)
	CVT24_008422	Uncharacterized protein. (1119 aa)
	CVT24_008910	Uncharacterized protein. (1374 aa)
	CVT24_008877	Uncharacterized protein. (1577 aa)
	CVT24_009497	Uncharacterized protein. (636 aa)
	CVT24_009492	Uncharacterized protein. (620 aa)
	CVT24_009064	Uncharacterized protein. (523 aa)
	CVT24_004296	Protein kinase domain-containing protein. (1390 aa)
	CVT24_004377	Thioredoxin domain-containing protein. (164 aa)
	CVT24_004984	FAD-binding PCMH-type domain-containing protein. (479 aa)
	CVT24_005928	Uncharacterized protein. (85 aa)
	CVT24_005505	Uncharacterized protein. (612 aa)
	CVT24_003276	Uncharacterized protein. (394 aa)
	CVT24_008224	Uncharacterized protein. (377 aa)
	CVT24_010432	Glutamate decarboxylase; Belongs to the group II decarboxylase family. (535 aa)
	CVT24_007103	F-box domain-containing protein. (242 aa)
	CVT24_007758	Glutamate decarboxylase; Belongs to the group II decarboxylase family. (534 aa)
	CVT24_010651	Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (385 aa)

Your Current Organism:

Panaeolus cyanescens

NCBI taxonomy Id: 181874
Other names: Copelandia cyanescens, P. cyanescens

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CVT24_000360	CVT24_005302	A0A409VRS1	A0A409Y8T3	Glutamate decarboxylase; Belongs to the group II decarboxylase family.	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	0.418
CVT24_000360	CVT24_005928	A0A409VRS1	A0A409V8Y3	Glutamate decarboxylase; Belongs to the group II decarboxylase family.	Uncharacterized protein.	0.416
CVT24_000360	CVT24_009008	A0A409VRS1	A0A409YAM6	Glutamate decarboxylase; Belongs to the group II decarboxylase family.	Uncharacterized protein.	0.400
CVT24_000963	CVT24_002628	A0A409YCE6	A0A409YU26	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	0.450
CVT24_000963	CVT24_003049	A0A409YCE6	A0A409W8Q7	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	0.619
CVT24_000963	CVT24_003275	A0A409YCE6	A0A409YRC0	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	Uncharacterized protein.	0.409
CVT24_000963	CVT24_003276	A0A409YCE6	A0A409YRB6	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	Uncharacterized protein.	0.409
CVT24_000963	CVT24_004565	A0A409YCE6	A0A409VE13	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	Glutaredoxin domain-containing protein.	0.557
CVT24_000963	CVT24_004957	A0A409YCE6	A0A409YB40	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	Thioredoxin domain-containing protein.	0.913
CVT24_000963	CVT24_005505	A0A409YCE6	A0A409YBZ2	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	Uncharacterized protein.	0.409
CVT24_000963	CVT24_006846	A0A409YCE6	A0A409YS05	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.810
CVT24_000963	CVT24_007715	A0A409YCE6	A0A409VRC0	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	Sod_Fe_C domain-containing protein.	0.409
CVT24_000963	CVT24_008342	A0A409YCE6	A0A409VE41	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	Thioredoxin domain-containing protein.	0.851
CVT24_000963	CVT24_009008	A0A409YCE6	A0A409YAM6	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	Uncharacterized protein.	0.778
CVT24_000963	CVT24_009168	A0A409YCE6	A0A409Y8D0	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	0.450
CVT24_000963	CVT24_010651	A0A409YCE6	A0A409YM20	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.	0.619
CVT24_000976	CVT24_003049	A0A409YCF0	A0A409W8Q7	Thioredoxin domain-containing protein.	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	0.407
CVT24_000976	CVT24_004957	A0A409YCF0	A0A409YB40	Thioredoxin domain-containing protein.	Thioredoxin domain-containing protein.	0.443
CVT24_000976	CVT24_006363	A0A409YCF0	A0A409YE66	Thioredoxin domain-containing protein.	PMSR domain-containing protein.	0.465
CVT24_000976	CVT24_006846	A0A409YCF0	A0A409YS05	Thioredoxin domain-containing protein.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.442