(6 nodes) Ketone body metabolism network (Panaeolus cyanescens)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Predicted Interactions

gene neighborhood

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textmining

co-expression

protein homology

Your Input:
	CVT24_003346	Uncharacterized protein. (652 aa)
	CVT24_003999	Uncharacterized protein. (704 aa)
	CVT24_005809	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (474 aa)
	CVT24_008914	Uncharacterized protein. (598 aa)
	CVT24_013153	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (526 aa)
	CVT24_000144	Pyruvate carboxyltransferase domain-containing protein. (360 aa)

Your Current Organism:

Panaeolus cyanescens

NCBI taxonomy Id: 181874
Other names: Copelandia cyanescens, P. cyanescens

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CVT24_000144	CVT24_003346	A0A409WBT8	A0A409Y760	Pyruvate carboxyltransferase domain-containing protein.	Uncharacterized protein.	0.900
CVT24_000144	CVT24_003999	A0A409WBT8	A0A409Y6D6	Pyruvate carboxyltransferase domain-containing protein.	Uncharacterized protein.	0.941
CVT24_000144	CVT24_005809	A0A409WBT8	A0A409V902	Pyruvate carboxyltransferase domain-containing protein.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.947
CVT24_000144	CVT24_008914	A0A409WBT8	A0A409VES7	Pyruvate carboxyltransferase domain-containing protein.	Uncharacterized protein.	0.753
CVT24_000144	CVT24_013153	A0A409WBT8	A0A409WA63	Pyruvate carboxyltransferase domain-containing protein.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.961
CVT24_003346	CVT24_000144	A0A409Y760	A0A409WBT8	Uncharacterized protein.	Pyruvate carboxyltransferase domain-containing protein.	0.900
CVT24_003346	CVT24_003999	A0A409Y760	A0A409Y6D6	Uncharacterized protein.	Uncharacterized protein.	0.872
CVT24_003346	CVT24_005809	A0A409Y760	A0A409V902	Uncharacterized protein.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.933
CVT24_003346	CVT24_013153	A0A409Y760	A0A409WA63	Uncharacterized protein.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.928
CVT24_003999	CVT24_000144	A0A409Y6D6	A0A409WBT8	Uncharacterized protein.	Pyruvate carboxyltransferase domain-containing protein.	0.941
CVT24_003999	CVT24_003346	A0A409Y6D6	A0A409Y760	Uncharacterized protein.	Uncharacterized protein.	0.872
CVT24_003999	CVT24_005809	A0A409Y6D6	A0A409V902	Uncharacterized protein.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.934
CVT24_003999	CVT24_013153	A0A409Y6D6	A0A409WA63	Uncharacterized protein.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.929
CVT24_005809	CVT24_000144	A0A409V902	A0A409WBT8	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Pyruvate carboxyltransferase domain-containing protein.	0.947
CVT24_005809	CVT24_003346	A0A409V902	A0A409Y760	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Uncharacterized protein.	0.933
CVT24_005809	CVT24_003999	A0A409V902	A0A409Y6D6	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Uncharacterized protein.	0.934
CVT24_005809	CVT24_013153	A0A409V902	A0A409WA63	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.944
CVT24_008914	CVT24_000144	A0A409VES7	A0A409WBT8	Uncharacterized protein.	Pyruvate carboxyltransferase domain-containing protein.	0.753
CVT24_008914	CVT24_013153	A0A409VES7	A0A409WA63	Uncharacterized protein.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.767
CVT24_013153	CVT24_000144	A0A409WA63	A0A409WBT8	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	Pyruvate carboxyltransferase domain-containing protein.	0.961