(6 nodes) Synthesis and degradation of ketone bodies network (Panaeolus cyanescens)

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Your Input:
	CVT24_013153	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (526 aa)
	CVT24_005809	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (474 aa)
	CVT24_000144	Pyruvate carboxyltransferase domain-containing protein. (360 aa)
	CVT24_006486	Thiolase_C domain-containing protein. (132 aa)
	CVT24_007789	Thiolase_C domain-containing protein. (132 aa)
	CVT24_008325	Thiolase_N domain-containing protein. (211 aa)

Your Current Organism:

Panaeolus cyanescens

NCBI taxonomy Id: 181874
Other names: Copelandia cyanescens, P. cyanescens

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CVT24_000144	CVT24_005809	A0A409WBT8	A0A409V902	Pyruvate carboxyltransferase domain-containing protein.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.947
CVT24_000144	CVT24_006486	A0A409WBT8	A0A409WSX2	Pyruvate carboxyltransferase domain-containing protein.	Thiolase_C domain-containing protein.	0.721
CVT24_000144	CVT24_007789	A0A409WBT8	A0A409WZ29	Pyruvate carboxyltransferase domain-containing protein.	Thiolase_C domain-containing protein.	0.721
CVT24_000144	CVT24_008325	A0A409WBT8	A0A409VCC6	Pyruvate carboxyltransferase domain-containing protein.	Thiolase_N domain-containing protein.	0.934
CVT24_000144	CVT24_013153	A0A409WBT8	A0A409WA63	Pyruvate carboxyltransferase domain-containing protein.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.961
CVT24_005809	CVT24_000144	A0A409V902	A0A409WBT8	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Pyruvate carboxyltransferase domain-containing protein.	0.947
CVT24_005809	CVT24_006486	A0A409V902	A0A409WSX2	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Thiolase_C domain-containing protein.	0.958
CVT24_005809	CVT24_007789	A0A409V902	A0A409WZ29	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Thiolase_C domain-containing protein.	0.958
CVT24_005809	CVT24_008325	A0A409V902	A0A409VCC6	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Thiolase_N domain-containing protein.	0.993
CVT24_005809	CVT24_013153	A0A409V902	A0A409WA63	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.944
CVT24_006486	CVT24_000144	A0A409WSX2	A0A409WBT8	Thiolase_C domain-containing protein.	Pyruvate carboxyltransferase domain-containing protein.	0.721
CVT24_006486	CVT24_005809	A0A409WSX2	A0A409V902	Thiolase_C domain-containing protein.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.958
CVT24_006486	CVT24_008325	A0A409WSX2	A0A409VCC6	Thiolase_C domain-containing protein.	Thiolase_N domain-containing protein.	0.951
CVT24_006486	CVT24_013153	A0A409WSX2	A0A409WA63	Thiolase_C domain-containing protein.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.744
CVT24_007789	CVT24_000144	A0A409WZ29	A0A409WBT8	Thiolase_C domain-containing protein.	Pyruvate carboxyltransferase domain-containing protein.	0.721
CVT24_007789	CVT24_005809	A0A409WZ29	A0A409V902	Thiolase_C domain-containing protein.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.958
CVT24_007789	CVT24_008325	A0A409WZ29	A0A409VCC6	Thiolase_C domain-containing protein.	Thiolase_N domain-containing protein.	0.951
CVT24_007789	CVT24_013153	A0A409WZ29	A0A409WA63	Thiolase_C domain-containing protein.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.744
CVT24_008325	CVT24_000144	A0A409VCC6	A0A409WBT8	Thiolase_N domain-containing protein.	Pyruvate carboxyltransferase domain-containing protein.	0.934
CVT24_008325	CVT24_005809	A0A409VCC6	A0A409V902	Thiolase_N domain-containing protein.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.993