(102 nodes) Lysine degradation network (Panaeolus cyanescens)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CVT24_008331	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (503 aa)
	CVT24_001495	SET domain-containing protein. (737 aa)
	CVT24_008630	SET domain-containing protein. (387 aa)
	CVT24_004787	MYND-type domain-containing protein. (363 aa)
	CVT24_005150	SET domain-containing protein. (1057 aa)
	CVT24_005633	Uncharacterized protein. (403 aa)
	CVT24_006726	F-box domain-containing protein. (659 aa)
	CVT24_005984	Uncharacterized protein. (447 aa)
	CVT24_006182	DAO domain-containing protein. (435 aa)
	CVT24_006895	Reverse transcriptase domain-containing protein. (1222 aa)
	CVT24_013103	Uncharacterized protein. (1577 aa)
	CVT24_013123	Isochorismatase domain-containing protein. (236 aa)
	CVT24_004662	Uncharacterized protein. (289 aa)
	CVT24_004657	F-box domain-containing protein. (738 aa)
	CVT24_004660	Uncharacterized protein. (320 aa)
	CVT24_004659	Uncharacterized protein. (432 aa)
	CVT24_004655	Uncharacterized protein. (332 aa)
	CVT24_000889	Uncharacterized protein. (269 aa)
	CVT24_002554	Uncharacterized protein. (1052 aa)
	CVT24_002527	Uncharacterized protein. (1267 aa)
	CVT24_002635	AlaDh_PNT_N domain-containing protein. (1047 aa)
	CVT24_001773	MYND-type domain-containing protein. (737 aa)
	CVT24_013065	MYND-type domain-containing protein. (405 aa)
	CVT24_011006	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (503 aa)
	CVT24_010609	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (494 aa)
	CVT24_007435	Uncharacterized protein. (290 aa)
	CVT24_010620	AB hydrolase-1 domain-containing protein. (496 aa)
	CVT24_010502	F-box domain-containing protein. (534 aa)
	CVT24_007413	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (502 aa)
	CVT24_007417	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (500 aa)
	CVT24_007414	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (492 aa)
	CVT24_011425	Rab-GAP TBC domain-containing protein. (1209 aa)
	CVT24_011389	SET domain-containing protein. (388 aa)
	CVT24_011333	Uncharacterized protein. (231 aa)
	CVT24_001299	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (474 aa)
	CVT24_001346	UCR_hinge domain-containing protein. (116 aa)
	CVT24_001521	F-box domain-containing protein. (431 aa)
	CVT24_005767	Saccharopine dehydrogenase [NAD(+), L-lysine-forming]; Belongs to the AlaDH/PNT family. (368 aa)
	CVT24_006014	Uncharacterized protein. (187 aa)
	CVT24_005456	Transket_pyr domain-containing protein. (946 aa)
	CVT24_004480	Uncharacterized protein. (287 aa)
	CVT24_004479	Uncharacterized protein. (341 aa)
	CVT24_004364	Uncharacterized protein. (595 aa)
	CVT24_004367	Uncharacterized protein. (466 aa)
	CVT24_004363	Uncharacterized protein. (470 aa)
	CVT24_009000	TauD domain-containing protein. (385 aa)
	CVT24_009027	Uncharacterized protein. (1097 aa)
	CVT24_005362	Thioredoxin domain-containing protein. (169 aa)
	CVT24_005172	F-box domain-containing protein. (548 aa)
	CVT24_009331	Uncharacterized protein. (491 aa)
	CVT24_003328	Uncharacterized protein. (877 aa)
	CVT24_003954	PHD-type domain-containing protein. (611 aa)
	CVT24_003307	Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily. (881 aa)
	CVT24_004024	Uncharacterized protein. (336 aa)
	CVT24_004127	YCII domain-containing protein; Belongs to the enoyl-CoA hydratase/isomerase family. (442 aa)
	CVT24_004028	Zn(2)-C6 fungal-type domain-containing protein. (835 aa)
	CVT24_004078	Fungal_trans domain-containing protein. (357 aa)
	CVT24_009936	Uncharacterized protein. (168 aa)
	CVT24_001386	Uncharacterized protein. (447 aa)
	CVT24_002604	F-box domain-containing protein. (429 aa)
	CVT24_002732	Uncharacterized protein. (602 aa)
	CVT24_006581	RNase H domain-containing protein. (830 aa)
	CVT24_006664	Reverse transcriptase domain-containing protein. (855 aa)
	CVT24_007789	Thiolase_C domain-containing protein. (132 aa)
	CVT24_002431	SET domain-containing protein. (186 aa)
	CVT24_012140	Reverse transcriptase domain-containing protein. (1261 aa)
	CVT24_012098	Reverse transcriptase domain-containing protein. (1300 aa)
	CVT24_008668	RNase H domain-containing protein. (1232 aa)
	CVT24_008804	Uncharacterized protein. (645 aa)
	CVT24_002936	SAP domain-containing protein. (998 aa)
	CVT24_006486	Thiolase_C domain-containing protein. (132 aa)
	CVT24_011716	Uncharacterized protein. (415 aa)
	CVT24_010143	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (504 aa)
	CVT24_013327	Uncharacterized protein. (272 aa)
	CVT24_002498	Uncharacterized protein. (647 aa)
	CVT24_001084	MYND-type domain-containing protein. (317 aa)
	CVT24_010524	Uncharacterized protein. (1095 aa)
	CVT24_003189	PHD domain-containing protein. (2275 aa)
	CVT24_003788	Lipoyl-binding domain-containing protein. (434 aa)
	CVT24_010848	Uncharacterized protein. (370 aa)
	CVT24_004793	Uncharacterized protein. (852 aa)
	CVT24_005582	Uncharacterized protein. (699 aa)
	CVT24_005583	Uncharacterized protein. (620 aa)
	CVT24_001362	SET domain-containing protein. (363 aa)
	CVT24_001074	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (523 aa)
	CVT24_000559	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. (615 aa)
	CVT24_012035	PABS domain-containing protein; Belongs to the spermidine/spermine synthase family. (754 aa)
	CVT24_006526	F-box domain-containing protein. (798 aa)
	CVT24_002347	Uncharacterized protein. (837 aa)
	CVT24_000195	Dihydrolipoyl dehydrogenase. (502 aa)
	CVT24_005043	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (420 aa)
	CVT24_011553	SET domain-containing protein. (313 aa)
	CVT24_007187	Uncharacterized protein. (279 aa)
	CVT24_011822	F-box domain-containing protein. (477 aa)
	CVT24_010805	DUF4470 domain-containing protein. (530 aa)
	CVT24_003224	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (531 aa)
	CVT24_008171	SET domain-containing protein. (473 aa)
	CVT24_008162	Uncharacterized protein. (303 aa)
	CVT24_005665	Post-SET domain-containing protein. (178 aa)
	CVT24_005745	Protein kinase domain-containing protein. (859 aa)
	CVT24_005795	Uncharacterized protein; Belongs to the aldehyde dehydrogenase family. (529 aa)
	CVT24_008325	Thiolase_N domain-containing protein. (211 aa)

Your Current Organism:

Panaeolus cyanescens

NCBI taxonomy Id: 181874
Other names: Copelandia cyanescens, P. cyanescens

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CVT24_000195	CVT24_001074	A0A409W327	A0A409VX31	Dihydrolipoyl dehydrogenase.	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.464
CVT24_000195	CVT24_003224	A0A409W327	A0A409VFV2	Dihydrolipoyl dehydrogenase.	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	0.405
CVT24_000195	CVT24_003788	A0A409W327	A0A409W860	Dihydrolipoyl dehydrogenase.	Lipoyl-binding domain-containing protein.	0.998
CVT24_000195	CVT24_005043	A0A409W327	A0A409VPM5	Dihydrolipoyl dehydrogenase.	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	0.464
CVT24_000195	CVT24_005362	A0A409W327	A0A409Y9H3	Dihydrolipoyl dehydrogenase.	Thioredoxin domain-containing protein.	0.807
CVT24_000195	CVT24_005456	A0A409W327	A0A409YC32	Dihydrolipoyl dehydrogenase.	Transket_pyr domain-containing protein.	0.988
CVT24_000195	CVT24_005795	A0A409W327	A0A409VCX0	Dihydrolipoyl dehydrogenase.	Uncharacterized protein; Belongs to the aldehyde dehydrogenase family.	0.767
CVT24_000195	CVT24_005984	A0A409W327	A0A409V8W5	Dihydrolipoyl dehydrogenase.	Uncharacterized protein.	0.937
CVT24_000195	CVT24_006182	A0A409W327	A0A409V8P1	Dihydrolipoyl dehydrogenase.	DAO domain-containing protein.	0.703
CVT24_000195	CVT24_009331	A0A409W327	A0A409Y899	Dihydrolipoyl dehydrogenase.	Uncharacterized protein.	0.451
CVT24_000195	CVT24_013123	A0A409W327	A0A409YP70	Dihydrolipoyl dehydrogenase.	Isochorismatase domain-containing protein.	0.993
CVT24_000559	CVT24_001362	A0A409VXB4	A0A409VTT0	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones.	SET domain-containing protein.	0.935
CVT24_000559	CVT24_001386	A0A409VXB4	A0A409X4M9	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones.	Uncharacterized protein.	0.908
CVT24_000559	CVT24_001495	A0A409VXB4	A0A409W359	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones.	SET domain-containing protein.	0.618
CVT24_000559	CVT24_002431	A0A409VXB4	A0A409WXH5	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones.	SET domain-containing protein.	0.811
CVT24_000559	CVT24_002498	A0A409VXB4	A0A409WBR7	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones.	Uncharacterized protein.	0.635
CVT24_000559	CVT24_003189	A0A409VXB4	A0A409W8D5	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones.	PHD domain-containing protein.	0.715
CVT24_000559	CVT24_003307	A0A409VXB4	A0A409Y6P3	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones.	Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.	0.969
CVT24_000559	CVT24_003954	A0A409VXB4	A0A409Y6Q2	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones.	PHD-type domain-containing protein.	0.609
CVT24_000559	CVT24_004024	A0A409VXB4	A0A409Y6E9	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones.	Uncharacterized protein.	0.533