(115 nodes) Tryptophan metabolism network (Panaeolus cyanescens)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CVT24_005404	Uncharacterized protein; Belongs to the cytochrome P450 family. (536 aa)
	CVT24_005984	Uncharacterized protein. (447 aa)
	CVT24_005663	F-box domain-containing protein. (649 aa)
	CVT24_004381	Uncharacterized protein. (1356 aa)
	CVT24_009489	Aminotran_1_2 domain-containing protein. (526 aa)
	CVT24_009117	Aminotran_1_2 domain-containing protein. (452 aa)
	CVT24_008331	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (503 aa)
	CVT24_008325	Thiolase_N domain-containing protein. (211 aa)
	CVT24_008730	Uncharacterized protein; Belongs to the metallo-dependent hydrolases superfamily. (547 aa)
	CVT24_008465	Uncharacterized protein; Belongs to the cytochrome P450 family. (538 aa)
	CVT24_008861	Uncharacterized protein. (535 aa)
	CVT24_003224	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (531 aa)
	CVT24_011500	Uncharacterized protein. (1358 aa)
	CVT24_000331	Uncharacterized protein. (247 aa)
	CVT24_005043	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (420 aa)
	BNA1	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate. (174 aa)
	CVT24_001377	Uncharacterized protein; Belongs to the cytochrome P450 family. (510 aa)
	CVT24_001217	Uncharacterized protein. (2510 aa)
	CVT24_013173	N-acetyltransferase domain-containing protein. (340 aa)
	CVT24_013274	Amino_oxidase domain-containing protein. (748 aa)
	CVT24_013279	Uncharacterized protein. (92 aa)
	CVT24_000834	F-box domain-containing protein. (626 aa)
	CVT24_001074	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (523 aa)
	CVT24_006466	Amidase domain-containing protein. (550 aa)
	CVT24_011977	Methyltransf_2 domain-containing protein. (485 aa)
	CVT24_007829	Aminotran_1_2 domain-containing protein. (420 aa)
	CVT24_002393	Uncharacterized protein. (462 aa)
	CVT24_003118	Uncharacterized protein. (1374 aa)
	CVT24_000195	Dihydrolipoyl dehydrogenase. (502 aa)
	CVT24_012482	Uncharacterized protein; Belongs to the cytochrome P450 family. (524 aa)
	CVT24_012480	Uncharacterized protein; Belongs to the cytochrome P450 family. (530 aa)
	CVT24_012481	Uncharacterized protein; Belongs to the cytochrome P450 family. (524 aa)
	CVT24_000033	Uncharacterized protein. (487 aa)
	CVT24_004354	Uncharacterized protein. (519 aa)
	CVT24_004187	Uncharacterized protein. (438 aa)
	CVT24_004186	Uncharacterized protein. (476 aa)
	CVT24_004191	Uncharacterized protein. (660 aa)
	CVT24_003788	Lipoyl-binding domain-containing protein. (434 aa)
	CVT24_010273	Uncharacterized protein; Belongs to the cytochrome P450 family. (536 aa)
	CVT24_010061	Amino_oxidase domain-containing protein. (329 aa)
	CVT24_010064	Uncharacterized protein. (490 aa)
	CVT24_010175	Uncharacterized protein. (647 aa)
	CVT24_012982	Abhydrolase_3 domain-containing protein. (265 aa)
	BNA4	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. (517 aa)
	BNA5	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (441 aa)
	CVT24_006551	Uncharacterized protein; Belongs to the FMO family. (648 aa)
	CVT24_006553	Uncharacterized protein. (640 aa)
	CVT24_013213	Uncharacterized protein. (387 aa)
	CVT24_008782	Amino_oxidase domain-containing protein. (363 aa)
	CVT24_010143	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (504 aa)
	CVT24_002623	Uncharacterized protein. (936 aa)
	CVT24_006486	Thiolase_C domain-containing protein. (132 aa)
	CVT24_007789	Thiolase_C domain-containing protein. (132 aa)
	CVT24_004076	Uncharacterized protein. (520 aa)
	CVT24_004127	YCII domain-containing protein; Belongs to the enoyl-CoA hydratase/isomerase family. (442 aa)
	CVT24_004049	Uncharacterized protein. (514 aa)
	CVT24_003967	Tr-type G domain-containing protein. (610 aa)
	CVT24_003357	Uncharacterized protein. (488 aa)
	CVT24_003601	Aminotran_1_2 domain-containing protein. (432 aa)
	CVT24_005402	Uncharacterized protein; Belongs to the cytochrome P450 family. (527 aa)
	CVT24_005393	Uncharacterized protein; Belongs to the cytochrome P450 family. (536 aa)
	CVT24_005397	Uncharacterized protein; Belongs to the cytochrome P450 family. (490 aa)
	CVT24_005398	Uncharacterized protein; Belongs to the cytochrome P450 family. (401 aa)
	CVT24_009608	Uncharacterized protein. (547 aa)
	CVT24_009543	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (500 aa)
	CVT24_009005	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Belongs to the catalase family. (864 aa)
	CVT24_008959	Amidase domain-containing protein. (586 aa)
	CVT24_005503	Uncharacterized protein. (235 aa)
	CVT24_005456	Transket_pyr domain-containing protein. (946 aa)
	CVT24_000321	Uncharacterized protein; Belongs to the FMO family. (668 aa)
	CVT24_006331	Methyltransf_2 domain-containing protein. (473 aa)
	CVT24_006330	Protein-S-isoprenylcysteine O-methyltransferase; Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family. (701 aa)
	CVT24_006348	Uncharacterized protein; Belongs to the cytochrome P450 family. (304 aa)
	CVT24_006311	Amino_oxidase domain-containing protein. (611 aa)
	CVT24_006312	Amino_oxidase domain-containing protein. (756 aa)
	CVT24_001870	Uncharacterized protein; Belongs to the cytochrome P450 family. (523 aa)
	CVT24_001886	Amidase domain-containing protein. (602 aa)
	CVT24_005869	Uncharacterized protein; Belongs to the cytochrome P450 family. (503 aa)
	CVT24_001803	Uncharacterized protein. (937 aa)
	CVT24_001726	Uncharacterized protein. (514 aa)
	CVT24_001729	Uncharacterized protein. (622 aa)
	CVT24_001299	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (474 aa)
	CVT24_011168	Uncharacterized protein. (517 aa)
	CVT24_011167	Uncharacterized protein. (562 aa)
	CVT24_011171	Uncharacterized protein. (452 aa)
	CVT24_011429	Uncharacterized protein. (405 aa)
	CVT24_011490	Uncharacterized protein. (1347 aa)
	CVT24_011710	Catalase domain-containing protein. (601 aa)
	CVT24_001997	Uncharacterized protein. (588 aa)
	CVT24_002149	Aminotran_1_2 domain-containing protein. (452 aa)
	CVT24_012433	Uncharacterized protein; Belongs to the cytochrome P450 family. (505 aa)
	CVT24_012381	Uncharacterized protein. (145 aa)
	CVT24_007008	Uncharacterized protein. (430 aa)
	CVT24_007414	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (492 aa)
	CVT24_007417	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (500 aa)
	CVT24_007413	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (502 aa)
	CVT24_012709	Uncharacterized protein; Belongs to the cytochrome P450 family. (503 aa)
	CVT24_008106	Uncharacterized protein; Belongs to the cytochrome P450 family. (443 aa)
	CVT24_008105	Uncharacterized protein; Belongs to the cytochrome P450 family. (557 aa)
	CVT24_010604	Amidohydro-rel domain-containing protein; Belongs to the metallo-dependent hydrolases superfamily. (385 aa)
	CVT24_010620	AB hydrolase-1 domain-containing protein. (496 aa)
	CVT24_010609	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (494 aa)
	CVT24_007096	Amidohydro-rel domain-containing protein; Belongs to the metallo-dependent hydrolases superfamily. (399 aa)
	CVT24_007073	Uncharacterized protein. (245 aa)
	CVT24_013123	Isochorismatase domain-containing protein. (236 aa)
	CVT24_010256	Uncharacterized protein. (527 aa)
	CVT24_002791	Uncharacterized protein. (512 aa)
	CVT24_013028	Uncharacterized protein. (620 aa)
	CVT24_011289	Uncharacterized protein. (445 aa)
	CVT24_011006	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (503 aa)
	CVT24_010974	Uncharacterized protein. (538 aa)
	CVT24_010718	Uncharacterized protein. (558 aa)
	CVT24_003757	Uncharacterized protein. (646 aa)
	CVT24_010883	Uncharacterized protein. (189 aa)
	CVT24_010838	F-box domain-containing protein. (708 aa)

Your Current Organism:

Panaeolus cyanescens

NCBI taxonomy Id: 181874
Other names: Copelandia cyanescens, P. cyanescens

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BNA1	BNA4	A0A409VSM3	A0A409WA77	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	0.839
BNA1	BNA5	A0A409VSM3	A0A409WAB0	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	0.977
BNA1	CVT24_001729	A0A409VSM3	A0A409YFR9	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	Uncharacterized protein.	0.495
BNA1	CVT24_003357	A0A409VSM3	A0A409Y798	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	Uncharacterized protein.	0.495
BNA1	CVT24_007096	A0A409VSM3	A0A409YNZ6	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	Amidohydro-rel domain-containing protein; Belongs to the metallo-dependent hydrolases superfamily.	0.817
BNA1	CVT24_008730	A0A409VSM3	A0A409VCU3	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	Uncharacterized protein; Belongs to the metallo-dependent hydrolases superfamily.	0.758
BNA1	CVT24_009005	A0A409VSM3	A0A409YAM4	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Belongs to the catalase family.	0.908
BNA1	CVT24_009543	A0A409VSM3	A0A409YAD2	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	0.908
BNA1	CVT24_010604	A0A409VSM3	A0A409YLW7	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	Amidohydro-rel domain-containing protein; Belongs to the metallo-dependent hydrolases superfamily.	0.924
BNA1	CVT24_011710	A0A409VSM3	A0A409YH73	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	Catalase domain-containing protein.	0.748
BNA1	CVT24_012982	A0A409VSM3	A0A409WA72	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	Abhydrolase_3 domain-containing protein.	0.441
BNA4	BNA1	A0A409WA77	A0A409VSM3	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	0.839
BNA4	BNA5	A0A409WA77	A0A409WAB0	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	0.992
BNA4	CVT24_000331	A0A409WA77	A0A409VIV8	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Uncharacterized protein.	0.530
BNA4	CVT24_001074	A0A409WA77	A0A409VX31	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.400
BNA4	CVT24_001729	A0A409WA77	A0A409YFR9	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Uncharacterized protein.	0.425
BNA4	CVT24_002149	A0A409WA77	A0A409YI42	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Aminotran_1_2 domain-containing protein.	0.633
BNA4	CVT24_003357	A0A409WA77	A0A409Y798	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Uncharacterized protein.	0.425
BNA4	CVT24_003601	A0A409WA77	A0A409Y7Z1	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Aminotran_1_2 domain-containing protein.	0.947
BNA4	CVT24_005043	A0A409WA77	A0A409VPM5	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	0.400