STRINGSTRING
OBF94521.1 OBF94521.1 pyrD pyrD OBF81500.1 OBF81500.1 OBF79533.1 OBF79533.1 add add folD folD A5791_01095 A5791_01095 OBF86151.1 OBF86151.1 OBF86199.1 OBF86199.1 OBF85321.1 OBF85321.1 OBF85322.1 OBF85322.1 OBF85388.1 OBF85388.1 OBF85325.1 OBF85325.1 cmk cmk pyrG pyrG OBF85349.1 OBF85349.1 nadK nadK OBF83789.1 OBF83789.1 OBF83736.1 OBF83736.1 OBF83669.1 OBF83669.1 upp upp OBF83488.1 OBF83488.1 nadD nadD nadE nadE ndk ndk OBF82885.1 OBF82885.1 plsB plsB OBF82878.1 OBF82878.1 OBF82626.1 OBF82626.1 OBF82639.1 OBF82639.1 OBF82557.1 OBF82557.1 OBF81891.1 OBF81891.1 ispH ispH OBF81943.1 OBF81943.1 coaA coaA OBF81611.1 OBF81611.1 OBF81100.1 OBF81100.1 OBF81330.1 OBF81330.1 OBF81161.1 OBF81161.1 OBF81209.1 OBF81209.1 coaX coaX OBF80685.1 OBF80685.1 OBF80701.1 OBF80701.1 OBF80517.1 OBF80517.1 OBF80525.1 OBF80525.1 guaB guaB OBF80533.1 OBF80533.1 guaA guaA OBF80463.1 OBF80463.1 OBF80436.1 OBF80436.1 OBF80437.1 OBF80437.1 pdxT pdxT pdxS pdxS OBF80215.1 OBF80215.1 OBF80247.1 OBF80247.1 OBF80230.1 OBF80230.1 OBF79976.1 OBF79976.1 OBF80013.1 OBF80013.1 OBF79828.1 OBF79828.1 OBF79829.1 OBF79829.1 OBF79830.1 OBF79830.1 OBF79832.1 OBF79832.1 moaA moaA OBF79904.1 OBF79904.1 pdxH pdxH OBF79863.1 OBF79863.1 OBF79631.1 OBF79631.1 coaE coaE OBF79659.1 OBF79659.1 OBF79679.1 OBF79679.1 OBF79746.1 OBF79746.1 OBF79688.1 OBF79688.1 nadA nadA OBF79696.1 OBF79696.1 OBF79710.1 OBF79710.1 purH purH purN purN OBF79171.1 OBF79171.1 OBF79172.1 OBF79172.1 OBF79180.1 OBF79180.1 ispG ispG dxr dxr OBF79199.1 OBF79199.1 pyrH pyrH OBF79203.1 OBF79203.1 fdhD fdhD OBF93787.1 OBF93787.1 OBF93802.1 OBF93802.1 OBF93822.1 OBF93822.1 OBF93322.1 OBF93322.1 OBF92835.1 OBF92835.1 OBF92845.1 OBF92845.1 pyrE pyrE purA purA OBF92943.1 OBF92943.1 OBF92864.1 OBF92864.1 OBF92873.1 OBF92873.1 ackA ackA thiE thiE OBF92881.1 OBF92881.1 OBF92882.1 OBF92882.1 thiG thiG OBF92894.1 OBF92894.1 thiC thiC OBF92909.1 OBF92909.1 psd psd OBF92912.1 OBF92912.1 OBF92620.1 OBF92620.1 OBF92402.1 OBF92402.1 dxs dxs gpsA gpsA OBF92104.1 OBF92104.1 OBF91801.1 OBF91801.1 gpsA-2 gpsA-2 thiL thiL OBF91134.1 OBF91134.1 OBF91056.1 OBF91056.1 glmU glmU prs prs OBF90863.1 OBF90863.1 ispE ispE OBF90856.1 OBF90856.1 OBF90672.1 OBF90672.1 OBF90677.1 OBF90677.1 OBF89472.1 OBF89472.1 OBF89484.1 OBF89484.1 OBF88462.1 OBF88462.1 OBF88463.1 OBF88463.1 OBF88481.1 OBF88481.1 OBF88493.1 OBF88493.1 OBF87831.1 OBF87831.1 purM purM purF purF purL purL OBF87880.1 OBF87880.1 purQ purQ purS purS purC purC OBF87893.1 OBF87893.1 purD purD OBF87933.1 OBF87933.1 OBF87995.1 OBF87995.1 ispF ispF ispD ispD OBF87420.1 OBF87420.1 OBF87426.1 OBF87426.1 OBF87427.1 OBF87427.1 OBF87272.1 OBF87272.1 OBF87182.1 OBF87182.1 OBF86733.1 OBF86733.1 acsA acsA OBF86797.1 OBF86797.1 OBF86802.1 OBF86802.1 folE folE OBF86628.1 OBF86628.1 OBF86338.1 OBF86338.1 OBF86350.1 OBF86350.1 atpC atpC atpD atpD atpG atpG atpF atpF atpF-2 atpF-2 atpE atpE atpB atpB adk adk OBF86041.1 OBF86041.1 OBF85846.1 OBF85846.1 OBF85863.1 OBF85863.1 OBF85726.1 OBF85726.1 coaD coaD fbiC fbiC OBF85595.1 OBF85595.1 pimE pimE OBF85552.1 OBF85552.1 OBF85508.1 OBF85508.1 OBF85459.1 OBF85459.1 gmk gmk pyrF pyrF carB carB carA carA OBF85467.1 OBF85467.1 pyrC pyrC pyrB pyrB dcd dcd OBF85020.1 OBF85020.1 OBF84448.1 OBF84448.1 OBF84472.1 OBF84472.1 OBF84487.1 OBF84487.1 purE purE purK purK apt apt OBF83995.1 OBF83995.1 dut dut OBF83886.1 OBF83886.1 OBF83913.1 OBF83913.1 thyX thyX OBF83941.1 OBF83941.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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OBF94521.1Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (437 aa)
pyrDDihydroorotate dehydrogenase (quinone); Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (356 aa)
OBF81500.1Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1058 aa)
OBF79533.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (242 aa)
addAdenosine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. (362 aa)
folDBifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (281 aa)
A5791_01095Amino acid oxidase; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (370 aa)
OBF86151.1Inositol 1-phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (368 aa)
OBF86199.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0301 (AlgH) family. (201 aa)
OBF85321.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (200 aa)
OBF85322.1Acyl-phosphate glycerol 3-phosphate acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (212 aa)
OBF85388.1CDP-alcohol phosphatidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (228 aa)
OBF85325.1Retinol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (339 aa)
cmkCytidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (227 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (586 aa)
OBF85349.1Thiamine pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (393 aa)
nadKNAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (306 aa)
OBF83789.1Betaine-aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (485 aa)
OBF83736.1Nicotinamidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (186 aa)
OBF83669.1Acid phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (283 aa)
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (207 aa)
OBF83488.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (111 aa)
nadDNicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (210 aa)
nadENAD(+) synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (684 aa)
ndkNucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (136 aa)
OBF82885.1Molybdenum cofactor guanylyltransferase; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family. (187 aa)
plsBGlycerol-3-phosphate acyltransferase; PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPAT/DAPAT family. (790 aa)
OBF82878.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (613 aa)
OBF82626.1Ribonucleotide-diphosphate reductase subunit beta; Catalyzes the rate-limiting step in dNTP synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (312 aa)
OBF82639.1Glycerol acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (294 aa)
OBF82557.1Thymidylate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (119 aa)
OBF81891.1Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (277 aa)
ispH4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (332 aa)
OBF81943.1Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (487 aa)
coaAType I pantothenate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (312 aa)
OBF81611.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (303 aa)
OBF81100.1Lysophospholipase; Derived by automated computational analysis using gene prediction method: Protein Homology. (277 aa)
OBF81330.1Class 1b ribonucleoside-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (320 aa)
OBF81161.1Polyphosphate kinase 2; Derived by automated computational analysis using gene prediction method: Protein Homology. (292 aa)
OBF81209.1Phospholipase; Derived by automated computational analysis using gene prediction method: Protein Homology. (485 aa)
coaXPantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (274 aa)
OBF80685.1NTP pyrophosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (161 aa)
OBF80701.1Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1051 aa)
OBF80517.1Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (505 aa)
OBF80525.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (2165 aa)
guaBIMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (535 aa)
OBF80533.1Inosine 5-monophosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (375 aa)
guaAGlutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. (513 aa)
OBF80463.1Glycerol acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (277 aa)
OBF80436.1Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (461 aa)
OBF80437.1Competence/damage-inducible protein A; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family. (431 aa)
pdxTGlutamine amidotransferase subunit PdxT; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (198 aa)
pdxSPyridoxal biosynthesis lyase PdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (303 aa)
OBF80215.1Alpha-(1-2)-phosphatidylinositol mannosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (374 aa)
OBF80247.1CDP-diacylglycerol--inositol 3-phosphatidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (221 aa)
OBF80230.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (524 aa)
OBF79976.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (472 aa)
OBF80013.1Phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (496 aa)
OBF79828.1Molybdenum cofactor biosynthesis protein C; Derived by automated computational analysis using gene prediction method: Protein Homology. (142 aa)
OBF79829.1Molybdenum cofactor biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (160 aa)
OBF79830.1Molybdenum cofactor biosynthesis protein MoaE; Derived by automated computational analysis using gene prediction method: Protein Homology. (142 aa)
OBF79832.1Molybdopterin synthase sulfur carrier subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (92 aa)
moaACyclic pyranopterin phosphate synthase; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (360 aa)
OBF79904.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (155 aa)
pdxHPyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (219 aa)
OBF79863.1Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1051 aa)
OBF79631.1Guanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (303 aa)
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (407 aa)
OBF79659.1Adenylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (431 aa)
OBF79679.1Inositol monophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (266 aa)
OBF79746.1Nicotinate-nucleotide diphosphorylase (carboxylating); Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family. (286 aa)
OBF79688.1L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (526 aa)
nadAQuinolinate synthase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (352 aa)
OBF79696.1Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (723 aa)
OBF79710.1Glycerol-3-phosphate acyltransferase; PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPAT/DAPAT family. (652 aa)
purHBifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (521 aa)
purNPhosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (217 aa)
OBF79171.1Hydrogenase assembly protein HupF; Derived by automated computational analysis using gene prediction method: Protein Homology. (243 aa)
OBF79172.1Phosphoheptose isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (220 aa)
OBF79180.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (457 aa)
ispG4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (384 aa)
dxr1-deoxy-D-xylulose-5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (401 aa)
OBF79199.1Phosphatidate cytidylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDS family. (306 aa)
pyrHUMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (247 aa)
OBF79203.1Glycerol acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (311 aa)
fdhDSufurtransferase FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. (273 aa)
OBF93787.1Pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (363 aa)
OBF93802.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (285 aa)
OBF93822.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (325 aa)
OBF93322.1Riboflavin biosynthesis protein RibF; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribF family. (330 aa)
OBF92835.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (269 aa)
OBF92845.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (282 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (178 aa)
purAAdenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (432 aa)
OBF92943.1Phosphoribosylglycinamide formyltransferase 2; Derived by automated computational analysis using gene prediction method: Protein Homology. (385 aa)
OBF92864.1acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (398 aa)
OBF92873.1Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (689 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (384 aa)
thiEThiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (221 aa)
OBF92881.1Glycine oxidase ThiO; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)
OBF92882.1Thiamine biosynthesis protein ThiS; Derived by automated computational analysis using gene prediction method: Protein Homology. (68 aa)
thiGThiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (252 aa)
OBF92894.1Bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (279 aa)
thiCPhosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (547 aa)
OBF92909.1CDP-diacylglycerol--serine O-phosphatidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (300 aa)
psdPhosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (235 aa)
OBF92912.1Molybdopterin molybdenumtransferase; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (401 aa)
OBF92620.1An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; Derived by automated computational analysis using gene prediction method: Protein Homology. (492 aa)
OBF92402.1Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (513 aa)
dxs1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (640 aa)
gpsANAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (341 aa)
OBF92104.1Alpha-mannosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (384 aa)
OBF91801.1Betaine-aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (485 aa)
gpsA-2Glycerol-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (339 aa)
thiLThiamine-phosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (320 aa)
OBF91134.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (490 aa)
OBF91056.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (491 aa)
glmUUDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (494 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (326 aa)
OBF90863.1Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1051 aa)
ispE4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (319 aa)
OBF90856.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (621 aa)
OBF90672.1Molybdopterin molybdenumtransferase; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (430 aa)
OBF90677.1Molybdenum cofactor biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (181 aa)
OBF89472.1Inosine 5-monophosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (478 aa)
OBF89484.1CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (208 aa)
OBF88462.1Acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (255 aa)
OBF88463.1Acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (260 aa)
OBF88481.1Regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (379 aa)
OBF88493.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (154 aa)
OBF87831.1Adenylate cyclase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (425 aa)
purMPhosphoribosylformylglycinamidine cyclo-ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (361 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (508 aa)
purLPhosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (754 aa)
OBF87880.1Glycerol acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (270 aa)
purQPhosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (224 aa)
purSPhosphoribosylformylglycinamidine synthase subunit PurS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] (79 aa)
purCPhosphoribosylaminoimidazolesuccinocarboxamide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SAICAR synthetase family. (297 aa)
OBF87893.1Adenylosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (472 aa)
purDPhosphoribosylamine--glycine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GARS family. (422 aa)
OBF87933.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (500 aa)
OBF87995.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphatidylserine decarboxylase family. (431 aa)
ispF2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (159 aa)
ispD2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (222 aa)
OBF87420.1Geranylgeranyl pyrophosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FPP/GGPP synthase family. (353 aa)
OBF87426.1Alpha-(1-2)-phosphatidylinositol mannosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (430 aa)
OBF87427.1Acyl-phosphate glycerol 3-phosphate acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (245 aa)
OBF87272.1Glycerol acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (270 aa)
OBF87182.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (374 aa)
OBF86733.1Metallophosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (318 aa)
acsAacetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (654 aa)
OBF86797.1Adenylyl cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (542 aa)
OBF86802.1Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (203 aa)
folEGTP cyclohydrolase I FolE; Derived by automated computational analysis using gene prediction method: Protein Homology. (202 aa)
OBF86628.1Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (373 aa)
OBF86338.1Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (432 aa)
OBF86350.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (540 aa)
atpCF0F1 ATP synthase subunit epsilon; Produces ATP from ADP in the presence of a proton gradient across the membrane. (121 aa)
atpDF0F1 ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (486 aa)
atpGF0F1 ATP synthase subunit gamma; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (309 aa)
atpFF0F1 ATP synthase subunit alpha; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction; Belongs to the ATPase delta chain family. (447 aa)
atpF-2F0F1 ATP synthase subunit B; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (170 aa)
atpEATP synthase F0 subunit C; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (81 aa)
atpBF0F1 ATP synthase subunit A; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family. (250 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (181 aa)
OBF86041.1Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (435 aa)
OBF85846.1Betaine-aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (484 aa)
OBF85863.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (86 aa)
OBF85726.1Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1052 aa)
coaDPantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (160 aa)
fbiC7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase; catalyzes radical-mediated transfer of hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO); functions in F420 biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (860 aa)
OBF85595.1Monoacyl phosphatidylinositol tetramannoside-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (642 aa)
pimEMannosyltransferase; Involved in the fifth mannose transfer of phosphatidylinositol mannoside synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (429 aa)
OBF85552.1Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (461 aa)
OBF85508.1Glycerol acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (246 aa)
OBF85459.1Phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (421 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (187 aa)
pyrFOrotidine 5'-phosphate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the OMP decarboxylase family. Type 2 subfamily. (278 aa)
carBCarbamoyl phosphate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarB family. (1121 aa)
carACarbamoyl phosphate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarA family. (375 aa)
OBF85467.1Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (168 aa)
pyrCDihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (434 aa)
pyrBAspartate carbamoyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (322 aa)
dcdDeoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. (190 aa)
OBF85020.1Diacylglycerol kinase; Involved in the biosynthesis of phosphatidylinositol mannosides (PIMs); the enzyme from Mycobacterium tuberculosis can phosphorylate a variety of amphipathic lipids; Derived by automated computational analysis using gene prediction method: Protein Homology. (312 aa)
OBF84448.1Diacylglycerol kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (321 aa)
OBF84472.1Polyphosphate kinase 2; Derived by automated computational analysis using gene prediction method: Protein Homology. (287 aa)
OBF84487.1Thymidylate kinase; Catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); Derived by automated computational analysis using gene prediction method: Protein Homology. (213 aa)
purE5-(carboxyamino)imidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (171 aa)
purK5-(carboxyamino)imidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (392 aa)
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (174 aa)
OBF83995.1GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (799 aa)
dutDeoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. (154 aa)
OBF83886.1Phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (536 aa)
OBF83913.1CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (196 aa)
thyXFAD-dependent thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. (250 aa)
OBF83941.1Thymidylate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (172 aa)
Your Current Organism:
Mycobacterium sp. 85200251163SCH5372311
NCBI taxonomy Id: 1834097
Other names: M. sp. 852002-51163_SCH5372311, Mycobacterium sp. 852002-51163_SCH5372311
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