STRINGSTRING
murA murA murB murB OBH06735.1 OBH06735.1 mraY mraY murD murD murG murG murC murC ftsQ ftsQ ftsZ ftsZ sepF sepF OBH06744.1 OBH06744.1 OBH06559.1 OBH06559.1 crgA crgA cwsA cwsA OBH06434.1 OBH06434.1 OBH06039.1 OBH06039.1 OBH05020.1 OBH05020.1 xerC xerC A5695_13245 A5695_13245 murE murE OBH13334.1 OBH13334.1 OBH12945.1 OBH12945.1 ftsE ftsE ligB ligB tig tig OBH12060.1 OBH12060.1 OBH12072.1 OBH12072.1 OBH11691.1 OBH11691.1 OBH11671.1 OBH11671.1 smc smc OBH11418.1 OBH11418.1 OBH11346.1 OBH11346.1 OBH10830.1 OBH10830.1 OBH10854.1 OBH10854.1 OBH10687.1 OBH10687.1 xerD xerD OBH09794.1 OBH09794.1 whiA whiA OBH08423.1 OBH08423.1 OBH08416.1 OBH08416.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (417 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (365 aa)
OBH06735.1UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. (521 aa)
mraYphospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (359 aa)
murDUDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (479 aa)
murGUndecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (403 aa)
murCUDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (486 aa)
ftsQCell division protein FtsQ; Essential cell division protein; Belongs to the FtsQ/DivIB family. FtsQ subfamily. (313 aa)
ftsZCell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (383 aa)
sepFCell division protein SepF; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. (213 aa)
OBH06744.1Cell wall synthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (268 aa)
OBH06559.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (247 aa)
crgACell division protein CrgA; Involved in cell division; Belongs to the CrgA family. (93 aa)
cwsACell wall synthesis protein CwsA; Required for regulated cell division, cell wall synthesis and the maintenance of cell shape; Belongs to the CwsA family. (144 aa)
OBH06434.1Septation inhibitor protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (220 aa)
OBH06039.1Transglycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (281 aa)
OBH05020.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (276 aa)
xerCRecombinase XerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. (298 aa)
A5695_13245Glycosyl transferase family 1; Incomplete; too short partial abutting assembly gap; missing stop; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (314 aa)
murEUDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (526 aa)
OBH13334.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (100 aa)
OBH12945.1Cell division protein FtsX; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily. (297 aa)
ftsECell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division. (229 aa)
ligBCarbon starvation protein CstA; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. (509 aa)
tigTrigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. (462 aa)
OBH12060.1ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (351 aa)
OBH12072.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (211 aa)
OBH11691.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (83 aa)
OBH11671.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (245 aa)
smcChromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1202 aa)
OBH11418.1Dipeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (441 aa)
OBH11346.1Cell division protein DivIVA; Derived by automated computational analysis using gene prediction method: Protein Homology. (115 aa)
OBH10830.1DNA repair ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (453 aa)
OBH10854.1Cell division protein FtsK; Derived by automated computational analysis using gene prediction method: Protein Homology. (762 aa)
OBH10687.1Cell division protein DivIVA; Derived by automated computational analysis using gene prediction method: Protein Homology. (233 aa)
xerDSite-specific tyrosine recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. (313 aa)
OBH09794.1SMC-Scp complex subunit ScpB; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. (231 aa)
whiADNA-binding protein WhiA; Involved in cell division and chromosome segregation. (325 aa)
OBH08423.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (279 aa)
OBH08416.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (308 aa)
Your Current Organism:
Mycobacterium sp. E1747
NCBI taxonomy Id: 1834128
Other names: M. sp. E1747
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