STRINGSTRING
OMC34372.1 OMC34372.1 OMC35907.1 OMC35907.1 OMC35908.1 OMC35908.1 glnD glnD OMC35911.1 OMC35911.1 OMC32678.1 OMC32678.1 OMC32679.1 OMC32679.1 OMC32597.1 OMC32597.1 OMC28946.1 OMC28946.1 OMC28487.1 OMC28487.1 OMC41723.1 OMC41723.1 pepA pepA OMC39817.1 OMC39817.1 OMC40008.1 OMC40008.1 OMC39819.1 OMC39819.1 glnE glnE OMC39820.1 OMC39820.1 OMC40011.1 OMC40011.1 OMC39821.1 OMC39821.1 OMC39962.1 OMC39962.1 OMC40034.1 OMC40034.1 OMC40035.1 OMC40035.1 OMC39120.1 OMC39120.1 OMC39105.1 OMC39105.1 OMC39106.1 OMC39106.1 OMC39107.1 OMC39107.1 OMC39108.1 OMC39108.1 OMC39109.1 OMC39109.1 OMC38247.1 OMC38247.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
OMC34372.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (262 aa)
OMC35907.1Ammonium transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (449 aa)
OMC35908.1Transcriptional regulator; Indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; Derived by automated computational analysis using gene prediction method: Protein Homology. (112 aa)
glnD[protein-PII] uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. (842 aa)
OMC35911.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (355 aa)
OMC32678.1N-acyl-L-amino acid amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (388 aa)
OMC32679.1Peptidase M20; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase M20A family. (394 aa)
OMC32597.1Gamma-glutamyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (651 aa)
OMC28946.1Ammonia channel protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (441 aa)
OMC28487.1Derived by automated computational analysis using gene prediction method: Protein Homology. (863 aa)
OMC41723.1Carboxylate--amine ligase; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. (368 aa)
pepALeucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (502 aa)
OMC39817.1Type I glutamate--ammonia ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (478 aa)
OMC40008.1LLM class F420-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (285 aa)
OMC39819.1Thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (209 aa)
glnEBifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of [...] (1000 aa)
OMC39820.1Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (446 aa)
OMC40011.1Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (487 aa)
OMC39821.1Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (510 aa)
OMC39962.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (279 aa)
OMC40034.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (324 aa)
OMC40035.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (518 aa)
OMC39120.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (238 aa)
OMC39105.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (869 aa)
OMC39106.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (308 aa)
OMC39107.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (341 aa)
OMC39108.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (277 aa)
OMC39109.1AAA family ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (460 aa)
OMC38247.1Glutamate--cysteine ligase; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. (376 aa)
Your Current Organism:
Mycobacterium sp. GA1841
NCBI taxonomy Id: 1834154
Other names: M. sp. GA-1841, Mycobacterium sp. GA-1841
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.