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ANU69088.1 ANU69088.1 A4V01_09345 A4V01_09345 ANU69112.1 ANU69112.1 ANU69193.1 ANU69193.1 ilvC ilvC hemA hemA ANU69484.1 ANU69484.1 ANU69492.1 ANU69492.1 ANU69544.1 ANU69544.1 dxr dxr ANU69594.1 ANU69594.1 aroK aroK aroE aroE gpsA gpsA argC argC ANU70103.1 ANU70103.1 ANU70113.1 ANU70113.1 ANU71491.1 ANU71491.1 ANU70236.1 ANU70236.1 ANU70271.1 ANU70271.1 proC proC ANU70474.1 ANU70474.1 ANU70487.1 ANU70487.1 ANU70571.1 ANU70571.1 zwf zwf ANU70621.1 ANU70621.1 ANU70636.1 ANU70636.1 ANU71347.1 ANU71347.1 ANU71342.1 ANU71342.1 ANU71338.2 ANU71338.2 ANU71325.1 ANU71325.1 ANU71297.1 ANU71297.1 ANU71283.1 ANU71283.1 ANU71281.1 ANU71281.1 ANU71278.1 ANU71278.1 ANU71250.1 ANU71250.1 ANU71236.1 ANU71236.1 gpsA-2 gpsA-2 ANU71161.1 ANU71161.1 ANU70935.1 ANU70935.1 ANU70929.1 ANU70929.1 ANU71523.1 ANU71523.1 asd asd ANU70878.1 ANU70878.1 ANU70803.1 ANU70803.1 proC-2 proC-2 ANU70754.1 ANU70754.1 ldh-2 ldh-2 ANU70705.1 ANU70705.1 ANU67464.1 ANU67464.1 ANU67465.1 ANU67465.1 ANU67499.1 ANU67499.1 ANU71385.2 ANU71385.2 ANU67567.1 ANU67567.1 ANU67647.1 ANU67647.1 ANU67651.1 ANU67651.1 ANU67663.1 ANU67663.1 ANU67666.1 ANU67666.1 ANU67673.1 ANU67673.1 ANU67675.1 ANU67675.1 ANU67732.1 ANU67732.1 ANU67792.1 ANU67792.1 ANU67799.1 ANU67799.1 ANU67908.1 ANU67908.1 ANU67921.1 ANU67921.1 ANU67930.1 ANU67930.1 ANU67996.1 ANU67996.1 folD folD ANU68057.1 ANU68057.1 dapB dapB ANU68136.1 ANU68136.1 ANU68221.1 ANU68221.1 ANU68229.1 ANU68229.1 ANU68293.1 ANU68293.1 ANU68296.1 ANU68296.1 ANU68297.1 ANU68297.1 ANU68302.1 ANU68302.1 ANU68304.1 ANU68304.1 ANU68307.1 ANU68307.1 ANU68316.1 ANU68316.1 ANU68317.1 ANU68317.1 ANU68318.1 ANU68318.1 ANU71422.1 ANU71422.1 ANU68585.1 ANU68585.1 ANU68623.1 ANU68623.1 ANU68630.1 ANU68630.1 rex rex ldh ldh ANU68904.1 ANU68904.1 ANU68965.1 ANU68965.1 ANU69058.1 ANU69058.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ANU69088.1NAD(P)-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (286 aa)
A4V01_09345Alanine dehydrogenase; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (149 aa)
ANU69112.1Potassium transporter TrkA; Derived by automated computational analysis using gene prediction method: Protein Homology. (223 aa)
ANU69193.1Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (443 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (331 aa)
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (403 aa)
ANU69484.1Siroheme synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (414 aa)
ANU69492.1Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (444 aa)
ANU69544.1Lactate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (326 aa)
dxr1-deoxy-D-xylulose-5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (388 aa)
ANU69594.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa)
aroKShikimate dehydrogenase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (421 aa)
aroEShikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (290 aa)
gpsAGlycerol-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (333 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (346 aa)
ANU70103.13-hydroxybutyryl-CoA dehydrogenase; Converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (279 aa)
ANU70113.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (316 aa)
ANU71491.1Hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (316 aa)
ANU70236.1Mannitol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (109 aa)
ANU70271.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (285 aa)
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (268 aa)
ANU70474.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (329 aa)
ANU70487.1Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (248 aa)
ANU70571.1beta-ketoacyl-ACP reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (243 aa)
zwfGlucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (467 aa)
ANU70621.1Phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (470 aa)
ANU70636.1Alpha-glucosidase/alpha-galactosidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (444 aa)
ANU71347.16-phosphogluconate dehydrogenase (decarboxylating); Derived by automated computational analysis using gene prediction method: Protein Homology. (297 aa)
ANU71342.1Hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (309 aa)
ANU71338.2Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (266 aa)
ANU71325.1NADP-dependent 6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (462 aa)
ANU71297.1Polysaccharide biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (631 aa)
ANU71283.1dTDP-glucose 4,6-dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (342 aa)
ANU71281.1N-acetylglucosamine transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (344 aa)
ANU71278.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (300 aa)
ANU71250.1UDP-glucose 4-epimerase GalE; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (336 aa)
ANU71236.13-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (329 aa)
gpsA-2Glycerol-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (333 aa)
ANU71161.1Type I glyceraldehyde-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (337 aa)
ANU70935.1dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (289 aa)
ANU70929.1dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (289 aa)
ANU71523.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (326 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (341 aa)
ANU70878.1Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (393 aa)
ANU70803.1Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (336 aa)
proC-2Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (266 aa)
ANU70754.1L-sorbose 1-phosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (416 aa)
ldh-2L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (316 aa)
ANU70705.13-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (388 aa)
ANU67464.1Mannitol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (362 aa)
ANU67465.1Sorbitol-6-phosphate 2-dehydrogenase; Converts D-sorbitol-dphosphate to D-fructose-6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (272 aa)
ANU67499.12-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (318 aa)
ANU71385.2Zn-dependent alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (347 aa)
ANU67567.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (330 aa)
ANU67647.1Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (261 aa)
ANU67651.1L-threonine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)
ANU67663.1Galactitol-1-phosphate 5-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (354 aa)
ANU67666.1Galactitol-1-phosphate 5-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (351 aa)
ANU67673.1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (351 aa)
ANU67675.1L-threonine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (342 aa)
ANU67732.1Prephenate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (282 aa)
ANU67792.1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (347 aa)
ANU67799.1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (347 aa)
ANU67908.13-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (310 aa)
ANU67921.13-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (310 aa)
ANU67930.1Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (329 aa)
ANU67996.1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (346 aa)
folDBifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (282 aa)
ANU68057.16-phospho-alpha-glucosidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (441 aa)
dapB4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (239 aa)
ANU68136.1Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (340 aa)
ANU68221.1Ketoacyl reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (250 aa)
ANU68229.1NAD(P)-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (430 aa)
ANU68293.13-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (309 aa)
ANU68296.1Mannitol-1-phosphate 5-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (392 aa)
ANU68297.1Mannitol-1-phosphate 5-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (348 aa)
ANU68302.1Sorbitol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (351 aa)
ANU68304.13-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (308 aa)
ANU68307.1Glycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (317 aa)
ANU68316.13-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (318 aa)
ANU68317.1Mannitol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (396 aa)
ANU68318.1Mannitol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (376 aa)
ANU71422.1NAD(P)-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (324 aa)
ANU68585.13-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (342 aa)
ANU68623.1SDR family oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (248 aa)
ANU68630.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (333 aa)
rexRedox-sensing transcriptional repressor Rex; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. (209 aa)
ldhHypothetical protein; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (316 aa)
ANU68904.1NAD-dependent malic enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. (390 aa)
ANU68965.1Potassium transporter Trk; Derived by automated computational analysis using gene prediction method: Protein Homology. (225 aa)
ANU69058.16-phospho-beta-glucosidase; Catalyzes the fromation of N-acetyl-D-glucosamine and N-acetyl-D-glucosamine-6-phosphate from diacetylchitobiose-6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (442 aa)
Your Current Organism:
Erysipelotrichaceae bacterium I46
NCBI taxonomy Id: 1834207
Other names: E. bacterium I46
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