(132 nodes) Microtubule cytoskeleton network (Penicillium arizonense)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1F5LR56	Uncharacterized protein. (904 aa)
	A0A1F5LQU0	Uncharacterized protein. (409 aa)
	A0A1F5LQT6	Uncharacterized protein. (197 aa)
	A0A1F5LQB4	Uncharacterized protein. (483 aa)
	A0A1F5LQB0	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (163 aa)
	A0A1F5LQ31	Uncharacterized protein. (354 aa)
	A0A1F5LQ27	Uncharacterized protein. (778 aa)
	A0A1F5LQ11	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (749 aa)
	A0A1F5LPW1	Csm1 domain-containing protein. (518 aa)
	A0A1F5LP49	Tubulin-specific chaperone A; Belongs to the TBCA family. (118 aa)
	A0A1F5LP31	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (385 aa)
	A0A1F5LNC8	Uncharacterized protein. (854 aa)
	A0A1F5LMJ4	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (961 aa)
	A0A1F5LLU0	CAP-Gly domain-containing protein. (651 aa)
	A0A1F5LLK1	Spindle pole body component. (878 aa)
	A0A1F5LLF0	GFA domain-containing protein. (137 aa)
	A0A1F5LLB4	Amino_oxidase domain-containing protein. (597 aa)
	A0A1F5LL37	Uncharacterized protein. (830 aa)
	A0A1F5LKN9	Putative glutathione-dependent formaldehyde-activating enzyme; Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione; Belongs to the Gfa family. (191 aa)
	A0A1F5LKM6	WD_REPEATS_REGION domain-containing protein. (1066 aa)
	A0A1F5LKC7	Uncharacterized protein. (280 aa)
	A0A1F5LK98	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1722 aa)
	A0A1F5LJW5	SUN domain-containing protein. (705 aa)
	A0A1F5LJQ1	Uncharacterized protein. (1209 aa)
	A0A1F5LJ57	Uncharacterized protein. (173 aa)
	A0A1F5LJ12	Spindle pole body component. (1025 aa)
	A0A1F5LIP5	NUDE_C domain-containing protein. (582 aa)
	A0A1F5LIN4	Uncharacterized protein. (384 aa)
	A0A1F5LIL6	Uncharacterized protein. (455 aa)
	A0A1F5LII0	G-patch domain-containing protein. (264 aa)
	A0A1F5LIE9	Uncharacterized protein. (1126 aa)
	A0A1F5LI91	J domain-containing protein. (986 aa)
	A0A1F5LI00	Spindle pole body component. (791 aa)
	A0A1F5LHQ6	Uncharacterized protein. (121 aa)
	nudF	Nuclear distribution protein nudF; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs. (418 aa)
	A0A1F5LHG5	GFA domain-containing protein. (137 aa)
	A0A1F5LHD7	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (452 aa)
	A0A1F5LHC2	TCTP domain-containing protein; Belongs to the TCTP family. (179 aa)
	A0A1F5LH84	Uncharacterized protein. (469 aa)
	A0A1F5LGC8	Uncharacterized protein. (938 aa)
	A0A1F5LFW6	Uncharacterized protein. (257 aa)
	A0A1F5LFQ1	Uncharacterized protein. (1236 aa)
	A0A1F5LFD0	Uncharacterized protein. (957 aa)
	A0A1F5LF78	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (324 aa)
	A0A1F5LF03	Dynein light chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures. (97 aa)
	A0A1F5LEN7	Uncharacterized protein. (1019 aa)
	A0A1F5LE54	Uncharacterized protein. (953 aa)
	A0A1F5LDQ7	Uncharacterized protein; Belongs to the calmodulin family. (196 aa)
	A0A1F5LDH9	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (496 aa)
	A0A1F5LD15	Uncharacterized protein. (275 aa)
	A0A1F5LCJ8	Serine/threonine-protein kinase. (1142 aa)
	A0A1F5LC20	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (601 aa)
	A0A1F5LBW3	Uncharacterized protein. (249 aa)
	A0A1F5LBU9	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (809 aa)
	A0A1F5LBQ0	Uncharacterized protein. (884 aa)
	A0A1F5LBN9	Uncharacterized protein. (628 aa)
	A0A1F5LBN0	Uncharacterized protein; Belongs to the actin family. (549 aa)
	A0A1F5LBE0	Rad51 domain-containing protein. (461 aa)
	A0A1F5LB91	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1164 aa)
	A0A1F5LB22	CAP-Gly domain-containing protein. (1370 aa)
	A0A1F5LAV4	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (796 aa)
	A0A1F5LAS3	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (871 aa)
	A0A1F5LAI4	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1184 aa)
	A0A1F5LAE0	Uncharacterized protein. (200 aa)
	A0A1F5L9S6	Uncharacterized protein. (858 aa)
	A0A1F5L9M8	Uncharacterized protein. (443 aa)
	A0A1F5L9G6	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (928 aa)
	A0A1F5L9E7	Protein kinase domain-containing protein. (298 aa)
	A0A1F5L9A2	C-CAP/cofactor C-like domain-containing protein. (403 aa)
	A0A1F5L955	Uncharacterized protein. (284 aa)
	A0A1F5L8Z0	INCENP_ARK-bind domain-containing protein. (1240 aa)
	A0A1F5L8F5	Rab-GAP TBC domain-containing protein. (441 aa)
	A0A1F5L822	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (322 aa)
	A0A1F5L807	PUA domain-containing protein. (472 aa)
	A0A1F5L7P0	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (834 aa)
	A0A1F5L7A6	Uncharacterized protein. (486 aa)
	A0A1F5L6V6	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (796 aa)
	A0A1F5L6M0	Uncharacterized protein. (647 aa)
	A0A1F5L6K5	Uncharacterized protein. (508 aa)
	A0A1F5L5V2	Uncharacterized protein. (697 aa)
	A0A1F5L593	Uncharacterized protein. (205 aa)
	A0A1F5L560	GFA domain-containing protein. (163 aa)
	A0A1F5L511	CAP-Gly domain-containing protein. (598 aa)
	A0A1F5L4Q1	Uncharacterized protein. (138 aa)
	A0A1F5L4J8	SGNH_hydro domain-containing protein. (259 aa)
	A0A1F5L4D4	AIP3 domain-containing protein. (1009 aa)
	A0A1F5L3T9	Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (348 aa)
	A0A1F5L3M0	Uncharacterized protein. (202 aa)
	A0A1F5L3I1	Uncharacterized protein. (497 aa)
	A0A1F5L3C7	Uncharacterized protein. (682 aa)
	A0A1F5L323	Uncharacterized protein. (123 aa)
	A0A1F5L2K4	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (450 aa)
	A0A1F5L1K4	Uncharacterized protein. (129 aa)
	A0A1F5L4N2	Uncharacterized protein. (78 aa)
	A0A1F5LYQ2	Uncharacterized protein. (162 aa)
	A0A1F5LZ22	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (400 aa)
	A0A1F5LZD0	NmrA domain-containing protein. (641 aa)
	A0A1F5LZD5	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (998 aa)
	A0A1F5LZJ4	CS domain-containing protein. (198 aa)
	A0A1F5LXW1	TYR_PHOSPHATASE_2 domain-containing protein. (605 aa)
	A0A1F5LXL0	Uncharacterized protein. (616 aa)
	A0A1F5LXB2	Uncharacterized protein. (4322 aa)
	A0A1F5LX27	Uncharacterized protein. (603 aa)
	A0A1F5LWR4	Ima1_N domain-containing protein. (907 aa)
	A0A1F5LW21	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (324 aa)
	A0A1F5LVX7	Spindle pole body component. (881 aa)
	A0A1F5LVV8	DUF2439 domain-containing protein. (648 aa)
	A0A1F5LVV3	MPN domain-containing protein. (350 aa)
	A0A1F5LVU2	CAP-Gly domain-containing protein. (278 aa)
	A0A1F5LVR3	Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (389 aa)
	A0A1F5LVH4	Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (496 aa)
	A0A1F5LVE1	Uncharacterized protein. (517 aa)
	A0A1F5LVB9	Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (711 aa)
	A0A1F5LV66	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (698 aa)
	A0A1F5LV64	Uncharacterized protein. (273 aa)
	A0A1F5LUX7	Peptidase C50 domain-containing protein. (2067 aa)
	A0A1F5LUR8	GFA domain-containing protein. (148 aa)
	A0A1F5LUD8	Spindle pole body component. (952 aa)
	A0A1F5LUB2	Uncharacterized protein. (840 aa)
	A0A1F5LU59	Uncharacterized protein; Belongs to the glycosyl hydrolase 17 family. (2615 aa)
	A0A1F5LU14	Uncharacterized protein. (438 aa)
	A0A1F5LTP6	SH3 domain-containing protein. (737 aa)
	A0A1F5LTL8	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (915 aa)
	A0A1F5LTK0	Uncharacterized protein. (74 aa)
	A0A1F5LT34	Uncharacterized protein. (1327 aa)
	A0A1F5LSZ8	Uncharacterized protein. (287 aa)
	A0A1F5LSL3	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (447 aa)
	A0A1F5LS10	SprT-like domain-containing protein. (674 aa)
	A0A1F5LRZ2	Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. (456 aa)
	A0A1F5LRY4	Uncharacterized protein. (253 aa)
	A0A1F5LRM9	Uncharacterized protein. (1790 aa)
	nudF-2	Nuclear distribution protein nudF; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs. (450 aa)

Your Current Organism:

Penicillium arizonense

NCBI taxonomy Id: 1835702
Other names: CBS 141311, Herb. C-F-101845, IBT 12289, P. arizonense, Penicillium arizonense Frisvad, Grijseels and J.C. Nielsen, 2016, Penicillium sp. JCN-2016

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1F5L1K4	A0A1F5L8Z0	A0A1F5L1K4	A0A1F5L8Z0	Uncharacterized protein.	INCENP_ARK-bind domain-containing protein.	0.512
A0A1F5L1K4	A0A1F5LNC8	A0A1F5L1K4	A0A1F5LNC8	Uncharacterized protein.	Uncharacterized protein.	0.687
A0A1F5L1K4	A0A1F5LP31	A0A1F5L1K4	A0A1F5LP31	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.651
A0A1F5L1K4	A0A1F5LQT6	A0A1F5L1K4	A0A1F5LQT6	Uncharacterized protein.	Uncharacterized protein.	0.418
A0A1F5L2K4	A0A1F5L3M0	A0A1F5L2K4	A0A1F5L3M0	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	Uncharacterized protein.	0.735
A0A1F5L2K4	A0A1F5L4J8	A0A1F5L2K4	A0A1F5L4J8	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	SGNH_hydro domain-containing protein.	0.786
A0A1F5L2K4	A0A1F5L511	A0A1F5L2K4	A0A1F5L511	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	CAP-Gly domain-containing protein.	0.650
A0A1F5L2K4	A0A1F5L5V2	A0A1F5L2K4	A0A1F5L5V2	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	Uncharacterized protein.	0.975
A0A1F5L2K4	A0A1F5L8F5	A0A1F5L2K4	A0A1F5L8F5	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	Rab-GAP TBC domain-containing protein.	0.523
A0A1F5L2K4	A0A1F5L955	A0A1F5L2K4	A0A1F5L955	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	Uncharacterized protein.	0.990
A0A1F5L2K4	A0A1F5L9E7	A0A1F5L2K4	A0A1F5L9E7	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	Protein kinase domain-containing protein.	0.792
A0A1F5L2K4	A0A1F5L9G6	A0A1F5L2K4	A0A1F5L9G6	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.868
A0A1F5L2K4	A0A1F5LAI4	A0A1F5L2K4	A0A1F5LAI4	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.912
A0A1F5L2K4	A0A1F5LAV4	A0A1F5L2K4	A0A1F5LAV4	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.622
A0A1F5L2K4	A0A1F5LBN0	A0A1F5L2K4	A0A1F5LBN0	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	Uncharacterized protein; Belongs to the actin family.	0.752
A0A1F5L2K4	A0A1F5LBU9	A0A1F5L2K4	A0A1F5LBU9	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.577
A0A1F5L2K4	A0A1F5LBW3	A0A1F5L2K4	A0A1F5LBW3	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	Uncharacterized protein.	0.908
A0A1F5L2K4	A0A1F5LC20	A0A1F5L2K4	A0A1F5LC20	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.504
A0A1F5L2K4	A0A1F5LCJ8	A0A1F5L2K4	A0A1F5LCJ8	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	Serine/threonine-protein kinase.	0.793
A0A1F5L2K4	A0A1F5LD15	A0A1F5L2K4	A0A1F5LD15	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	Uncharacterized protein.	0.622

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