(74 nodes) Alanine, aspartate and glutamate metabolism network (Penicillium arizonense)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1F5LSN5	Aspartate aminotransferase. (404 aa)
	A0A1F5L1N9	Uncharacterized protein. (266 aa)
	A0A1F5L2J3	Gln-synt_C domain-containing protein; Belongs to the glutamine synthetase family. (486 aa)
	A0A1F5L3F5	Aminotran_5 domain-containing protein. (445 aa)
	A0A1F5L3Z0	Amino_oxidase domain-containing protein. (728 aa)
	A0A1F5L465	Uncharacterized protein. (150 aa)
	A0A1F5L4F6	Uncharacterized protein. (107 aa)
	A0A1F5L4Q3	Uncharacterized protein. (256 aa)
	A0A1F5L4U0	Aldedh domain-containing protein. (494 aa)
	A0A1F5L5D5	Glutamine amidotransferase type-2 domain-containing protein. (579 aa)
	A0A1F5L5W4	Aspartate aminotransferase. (416 aa)
	A0A1F5L6D2	Zn(2)-C6 fungal-type domain-containing protein. (958 aa)
	A0A1F5L6K2	Uncharacterized protein. (416 aa)
	A0A1F5L738	Uncharacterized protein. (694 aa)
	A0A1F5L7P1	Uncharacterized protein. (432 aa)
	A0A1F5L7U1	Glutamate decarboxylase; Belongs to the group II decarboxylase family. (492 aa)
	A0A1F5L7Y2	Aminotran_1_2 domain-containing protein. (499 aa)
	A0A1F5L867	Aldedh domain-containing protein. (555 aa)
	A0A1F5L8F8	Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. (579 aa)
	A0A1F5L8L8	Aspartate aminotransferase. (531 aa)
	A0A1F5LA57	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (489 aa)
	A0A1F5LAL8	Glutamine amidotransferase type-2 domain-containing protein. (572 aa)
	A0A1F5LAR8	Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (460 aa)
	A0A1F5LBQ7	Aldedh domain-containing protein. (500 aa)
	A0A1F5LBX2	Aldedh domain-containing protein. (495 aa)
	A0A1F5LCA9	Aldedh domain-containing protein. (479 aa)
	A0A1F5LCX1	Uncharacterized protein. (569 aa)
	A0A1F5LDS1	Glutamine amidotransferase type-2 domain-containing protein. (2124 aa)
	A0A1F5LDW7	Aspartate aminotransferase. (418 aa)
	A0A1F5LE62	Amidophosphoribosyltransferase. (579 aa)
	A0A1F5LEQ9	Aspartate aminotransferase. (428 aa)
	A0A1F5LEV8	Succinate-semialdehyde dehydrogenase. (498 aa)
	A0A1F5LEW4	Uncharacterized protein. (774 aa)
	A0A1F5LEZ9	Nfu_N domain-containing protein. (318 aa)
	A0A1F5LFL4	Uncharacterized protein. (2243 aa)
	A0A1F5LFU6	NAD-specific glutamate dehydrogenase; NAD(+)-dependent glutamate dehydrogenase which degrades glutamate to ammonia and alpha-ketoglutarate. Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (1087 aa)
	A0A1F5LGS3	Uncharacterized protein. (1221 aa)
	A0A1F5LGV8	Aminotran_1_2 domain-containing protein. (407 aa)
	A0A1F5LHG2	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (423 aa)
	A0A1F5LHJ9	AB hydrolase-1 domain-containing protein. (368 aa)
	A0A1F5LI39	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (471 aa)
	A0A1F5LJA9	Uncharacterized protein; Belongs to the asparaginase 1 family. (377 aa)
	A0A1F5LJM4	Uncharacterized protein. (560 aa)
	A0A1F5LJQ4	Aldedh domain-containing protein. (152 aa)
	A0A1F5LKF6	Amino_oxidase domain-containing protein. (696 aa)
	A0A1F5LL19	Aminotran_1_2 domain-containing protein. (433 aa)
	A0A1F5LL42	Uncharacterized protein. (1169 aa)
	A0A1F5LLB4	Amino_oxidase domain-containing protein. (597 aa)
	A0A1F5LLK4	Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (483 aa)
	A0A1F5LM29	Uncharacterized protein. (169 aa)
	A0A1F5LM62	Gln-synt_C domain-containing protein; Belongs to the glutamine synthetase family. (865 aa)
	A0A1F5LMT9	Aldedh domain-containing protein. (498 aa)
	A0A1F5LNC7	AAA domain-containing protein; Belongs to the AAA ATPase family. (418 aa)
	A0A1F5LNE4	Uncharacterized protein. (464 aa)
	A0A1F5LPT7	Uncharacterized protein. (118 aa)
	A0A1F5LR11	CN hydrolase domain-containing protein. (293 aa)
	A0A1F5LRJ0	Glutamate decarboxylase; Belongs to the group II decarboxylase family. (512 aa)
	A0A1F5LRV4	Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. (571 aa)
	A0A1F5LSF3	Glutamine amidotransferase type-1 domain-containing protein; Belongs to the aldehyde dehydrogenase family. (680 aa)
	A0A1F5LSH4	Glutamine amidotransferase type-2 domain-containing protein. (663 aa)
	A0A1F5LSH5	Gln-synt_C domain-containing protein; Belongs to the glutamine synthetase family. (462 aa)
	A0A1F5LT23	Glutamine amidotransferase type-2 domain-containing protein. (377 aa)
	A0A1F5LTL9	Uncharacterized protein. (382 aa)
	aguA	Alpha-glucuronidase; Alpha-glucuronidase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose. Releases 4-O-methylglucuronic acid from xylan. Belongs to the glycosyl hydrolase 67 family. (834 aa)
	A0A1F5LV59	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (463 aa)
	A0A1F5LVC0	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (498 aa)
	A0A1F5LW49	ANK_REP_REGION domain-containing protein. (556 aa)
	A0A1F5LW81	ADSL_C domain-containing protein. (439 aa)
	A0A1F5LX24	Aldedh domain-containing protein. (477 aa)
	A0A1F5LX56	Glutamine amidotransferase type-1 domain-containing protein. (453 aa)
	A0A1F5LYG1	Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. (577 aa)
	A0A1F5LYT8	Aldedh domain-containing protein. (504 aa)
	A0A1F5LZG3	Uncharacterized protein. (858 aa)
	A0A1F5M052	Uncharacterized protein. (521 aa)

Your Current Organism:

Penicillium arizonense

NCBI taxonomy Id: 1835702
Other names: CBS 141311, Herb. C-F-101845, IBT 12289, P. arizonense, Penicillium arizonense Frisvad, Grijseels and J.C. Nielsen, 2016, Penicillium sp. JCN-2016

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1F5L1N9	A0A1F5L2J3	A0A1F5L1N9	A0A1F5L2J3	Uncharacterized protein.	Gln-synt_C domain-containing protein; Belongs to the glutamine synthetase family.	0.484
A0A1F5L1N9	A0A1F5L5D5	A0A1F5L1N9	A0A1F5L5D5	Uncharacterized protein.	Glutamine amidotransferase type-2 domain-containing protein.	0.552
A0A1F5L1N9	A0A1F5L5W4	A0A1F5L1N9	A0A1F5L5W4	Uncharacterized protein.	Aspartate aminotransferase.	0.505
A0A1F5L1N9	A0A1F5L738	A0A1F5L1N9	A0A1F5L738	Uncharacterized protein.	Uncharacterized protein.	0.560
A0A1F5L1N9	A0A1F5L7U1	A0A1F5L1N9	A0A1F5L7U1	Uncharacterized protein.	Glutamate decarboxylase; Belongs to the group II decarboxylase family.	0.480
A0A1F5L1N9	A0A1F5L7Y2	A0A1F5L1N9	A0A1F5L7Y2	Uncharacterized protein.	Aminotran_1_2 domain-containing protein.	0.487
A0A1F5L1N9	A0A1F5L8L8	A0A1F5L1N9	A0A1F5L8L8	Uncharacterized protein.	Aspartate aminotransferase.	0.505
A0A1F5L1N9	A0A1F5LAL8	A0A1F5L1N9	A0A1F5LAL8	Uncharacterized protein.	Glutamine amidotransferase type-2 domain-containing protein.	0.650
A0A1F5L1N9	A0A1F5LCX1	A0A1F5L1N9	A0A1F5LCX1	Uncharacterized protein.	Uncharacterized protein.	0.560
A0A1F5L1N9	A0A1F5LDS1	A0A1F5L1N9	A0A1F5LDS1	Uncharacterized protein.	Glutamine amidotransferase type-2 domain-containing protein.	0.656
A0A1F5L1N9	A0A1F5LDW7	A0A1F5L1N9	A0A1F5LDW7	Uncharacterized protein.	Aspartate aminotransferase.	0.505
A0A1F5L1N9	A0A1F5LE62	A0A1F5L1N9	A0A1F5LE62	Uncharacterized protein.	Amidophosphoribosyltransferase.	0.727
A0A1F5L1N9	A0A1F5LEQ9	A0A1F5L1N9	A0A1F5LEQ9	Uncharacterized protein.	Aspartate aminotransferase.	0.560
A0A1F5L1N9	A0A1F5LFL4	A0A1F5L1N9	A0A1F5LFL4	Uncharacterized protein.	Uncharacterized protein.	0.891
A0A1F5L1N9	A0A1F5LGV8	A0A1F5L1N9	A0A1F5LGV8	Uncharacterized protein.	Aminotran_1_2 domain-containing protein.	0.560
A0A1F5L1N9	A0A1F5LHG2	A0A1F5L1N9	A0A1F5LHG2	Uncharacterized protein.	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	0.654
A0A1F5L1N9	A0A1F5LJA9	A0A1F5L1N9	A0A1F5LJA9	Uncharacterized protein.	Uncharacterized protein; Belongs to the asparaginase 1 family.	0.569
A0A1F5L1N9	A0A1F5LJM4	A0A1F5L1N9	A0A1F5LJM4	Uncharacterized protein.	Uncharacterized protein.	0.605
A0A1F5L1N9	A0A1F5LL19	A0A1F5L1N9	A0A1F5LL19	Uncharacterized protein.	Aminotran_1_2 domain-containing protein.	0.505
A0A1F5L1N9	A0A1F5LL42	A0A1F5L1N9	A0A1F5LL42	Uncharacterized protein.	Uncharacterized protein.	0.891

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