STRINGSTRING
LOC111663999 LOC111663999 orc3 orc3 gins1 gins1 orc2 orc2 LOC111647723 LOC111647723 mcm6 mcm6 timeless timeless cdc45 cdc45 MCMDC2 MCMDC2 gins3 gins3 mcm2 mcm2 ENSSLDP00000009544 ENSSLDP00000009544 ENSSLDP00000009655 ENSSLDP00000009655 Mcm9 Mcm9 tipin tipin gins4 gins4 orc4 orc4 mcm4 mcm4 mcm10 mcm10 dbf4 dbf4 LOC111658782 LOC111658782 orc1 orc1 cdc7 cdc7 orc5 orc5 mcm8 mcm8 cdt1 cdt1 LOC111657090 LOC111657090 gins2 gins2 mcm3 mcm3 mcmbp mcmbp wdhd1 wdhd1 ENSSLDP00000028086 ENSSLDP00000028086 CLSPN CLSPN PIEZO2 PIEZO2 ENSSLDP00000030197 ENSSLDP00000030197 ENSSLDP00000030223 ENSSLDP00000030223 mcm7 mcm7 mcm5 mcm5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC111663999Sld5 domain-containing protein. (113 aa)
orc3Origin recognition complex, subunit 3. (722 aa)
gins1GINS complex subunit 1 (Psf1 homolog). (196 aa)
orc2Origin recognition complex, subunit 2. (577 aa)
LOC111647723TIMELESS domain-containing protein. (404 aa)
mcm6DNA helicase; Belongs to the MCM family. (816 aa)
timelessTimeless circadian clock. (1019 aa)
cdc45CDC45 cell division cycle 45 homolog (S. cerevisiae). (569 aa)
MCMDC2Minichromosome maintenance domain containing 2. (644 aa)
gins3GINS complex subunit 3. (211 aa)
mcm2DNA helicase; Belongs to the MCM family. (888 aa)
ENSSLDP00000009544PIEZO domain-containing protein. (449 aa)
ENSSLDP00000009655Uncharacterized protein. (545 aa)
Mcm9Uncharacterized protein. (108 aa)
tipinTIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (330 aa)
gins4DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (226 aa)
orc4Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (457 aa)
mcm4DNA helicase; Belongs to the MCM family. (907 aa)
mcm10Minichromosome maintenance 10 replication initiation factor. (920 aa)
dbf4DBF4 zinc finger. (617 aa)
LOC111658782Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (444 aa)
orc1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (859 aa)
cdc7Cell division cycle 7 homolog (S. cerevisiae). (623 aa)
orc5Origin recognition complex, subunit 5. (445 aa)
mcm8Minichromosome maintenance 8 homologous recombination repair factor; Belongs to the MCM family. (782 aa)
cdt1Chromatin licensing and DNA replication factor 1. (610 aa)
LOC111657090DBF4-type domain-containing protein. (840 aa)
gins2DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (186 aa)
mcm3DNA helicase; Belongs to the MCM family. (815 aa)
mcmbpMinichromosome maintenance complex binding protein. (634 aa)
wdhd1WD repeat and HMG-box DNA binding protein 1. (999 aa)
ENSSLDP00000028086AAA_16 domain-containing protein. (309 aa)
CLSPNClaspin. (908 aa)
PIEZO2Piezo-type mechanosensitive ion channel component. (2641 aa)
ENSSLDP00000030197Uncharacterized protein. (303 aa)
ENSSLDP00000030223Piezo_RRas_bdg domain-containing protein. (581 aa)
mcm7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (727 aa)
mcm5DNA helicase; Belongs to the MCM family. (737 aa)
Your Current Organism:
Seriola lalandi
NCBI taxonomy Id: 1841481
Other names: S. lalandi dorsalis, Seriola dorsalis, Seriola lalandi dorsalis
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