18 items (Seriola lalandi) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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Predicted Interactions

gene neighborhood

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protein homology

Your Input:
	orc3	Origin recognition complex, subunit 3. (722 aa)
	orc2	Origin recognition complex, subunit 2. (577 aa)
	mcm6	DNA helicase; Belongs to the MCM family. (816 aa)
	cdc45	CDC45 cell division cycle 45 homolog (S. cerevisiae). (569 aa)
	MCMDC2	Minichromosome maintenance domain containing 2. (644 aa)
	mcm2	DNA helicase; Belongs to the MCM family. (888 aa)
	Mcm9	Uncharacterized protein. (108 aa)
	orc4	Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (457 aa)
	mcm10	Minichromosome maintenance 10 replication initiation factor. (920 aa)
	dbf4	DBF4 zinc finger. (617 aa)
	orc1	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (859 aa)
	cdc7	Cell division cycle 7 homolog (S. cerevisiae). (623 aa)
	orc5	Origin recognition complex, subunit 5. (445 aa)
	cdt1	Chromatin licensing and DNA replication factor 1. (610 aa)
	mcm3	DNA helicase; Belongs to the MCM family. (815 aa)
	ENSSLDP00000028086	AAA_16 domain-containing protein. (309 aa)
	mcm7	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (727 aa)
	mcm5	DNA helicase; Belongs to the MCM family. (737 aa)

Your Current Organism:

Seriola lalandi

NCBI taxonomy Id: 1841481
Other names: S. lalandi dorsalis, Seriola dorsalis, Seriola lalandi dorsalis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSLDP00000028086	MCMDC2	ENSSLDP00000028086	ENSSLDP00000007278	AAA_16 domain-containing protein.	Minichromosome maintenance domain containing 2.	0.960
ENSSLDP00000028086	Mcm9	ENSSLDP00000028086	ENSSLDP00000009849	AAA_16 domain-containing protein.	Uncharacterized protein.	0.979
ENSSLDP00000028086	cdc45	ENSSLDP00000028086	ENSSLDP00000006206	AAA_16 domain-containing protein.	CDC45 cell division cycle 45 homolog (S. cerevisiae).	0.937
ENSSLDP00000028086	cdc7	ENSSLDP00000028086	ENSSLDP00000021018	AAA_16 domain-containing protein.	Cell division cycle 7 homolog (S. cerevisiae).	0.855
ENSSLDP00000028086	cdt1	ENSSLDP00000028086	ENSSLDP00000023234	AAA_16 domain-containing protein.	Chromatin licensing and DNA replication factor 1.	0.995
ENSSLDP00000028086	dbf4	ENSSLDP00000028086	ENSSLDP00000018556	AAA_16 domain-containing protein.	DBF4 zinc finger.	0.802
ENSSLDP00000028086	mcm10	ENSSLDP00000028086	ENSSLDP00000018066	AAA_16 domain-containing protein.	Minichromosome maintenance 10 replication initiation factor.	0.982
ENSSLDP00000028086	mcm2	ENSSLDP00000028086	ENSSLDP00000008653	AAA_16 domain-containing protein.	DNA helicase; Belongs to the MCM family.	0.994
ENSSLDP00000028086	mcm3	ENSSLDP00000028086	ENSSLDP00000025695	AAA_16 domain-containing protein.	DNA helicase; Belongs to the MCM family.	0.992
ENSSLDP00000028086	mcm5	ENSSLDP00000028086	ENSSLDP00000031713	AAA_16 domain-containing protein.	DNA helicase; Belongs to the MCM family.	0.992
ENSSLDP00000028086	mcm6	ENSSLDP00000028086	ENSSLDP00000005466	AAA_16 domain-containing protein.	DNA helicase; Belongs to the MCM family.	0.994
ENSSLDP00000028086	mcm7	ENSSLDP00000028086	ENSSLDP00000031664	AAA_16 domain-containing protein.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.993
ENSSLDP00000028086	orc1	ENSSLDP00000028086	ENSSLDP00000018812	AAA_16 domain-containing protein.	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	0.996
ENSSLDP00000028086	orc2	ENSSLDP00000028086	ENSSLDP00000005124	AAA_16 domain-containing protein.	Origin recognition complex, subunit 2.	0.978
ENSSLDP00000028086	orc3	ENSSLDP00000028086	ENSSLDP00000004200	AAA_16 domain-containing protein.	Origin recognition complex, subunit 3.	0.976
ENSSLDP00000028086	orc4	ENSSLDP00000028086	ENSSLDP00000013242	AAA_16 domain-containing protein.	Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family.	0.977
ENSSLDP00000028086	orc5	ENSSLDP00000028086	ENSSLDP00000022870	AAA_16 domain-containing protein.	Origin recognition complex, subunit 5.	0.977
MCMDC2	ENSSLDP00000028086	ENSSLDP00000007278	ENSSLDP00000028086	Minichromosome maintenance domain containing 2.	AAA_16 domain-containing protein.	0.960
MCMDC2	Mcm9	ENSSLDP00000007278	ENSSLDP00000009849	Minichromosome maintenance domain containing 2.	Uncharacterized protein.	0.975
MCMDC2	cdc45	ENSSLDP00000007278	ENSSLDP00000006206	Minichromosome maintenance domain containing 2.	CDC45 cell division cycle 45 homolog (S. cerevisiae).	0.982