STRINGSTRING
LOC111662457 LOC111662457 polk polk lig4 lig4 LOC111663385 LOC111663385 LOC111658533 LOC111658533 LOC111668343 LOC111668343 xab2 xab2 mnat1 mnat1 ENSSLDP00000006566 ENSSLDP00000006566 ogg1 ogg1 pold3 pold3 ercc1 ercc1 pold1 pold1 ENSSLDP00000008454 ENSSLDP00000008454 RAD23B RAD23B ENSSLDP00000020317 ENSSLDP00000020317 xpa xpa gtf2h3 gtf2h3 fancc fancc sirt1 sirt1 gtf2h5 gtf2h5 ercc2 ercc2 ercc8 ercc8 RPA1 RPA1 LOC111644662 LOC111644662 gtf2h1 gtf2h1 rpa3 rpa3 ENSSLDP00000029977 ENSSLDP00000029977 ddb2 ddb2 LOC111646515 LOC111646515 pole pole ercc4 ercc4 uvssa uvssa usp7 usp7 ercc3 ercc3 LOC111652014 LOC111652014 polr2i polr2i LOC111647896 LOC111647896 poll poll LOC111653873 LOC111653873 hus1 hus1 LOC111671696 LOC111671696 NTHL1 NTHL1 bivm bivm slx4 slx4 ercc6 ercc6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC111662457RAD23 homolog A, nucleotide excision repair protein a. (371 aa)
polkPolymerase (DNA directed) kappa. (883 aa)
lig4DNA ligase. (900 aa)
LOC111663385BRCT domain-containing protein. (216 aa)
LOC111658533Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (962 aa)
LOC111668343Excision repair cross-complementation group 5. (982 aa)
xab2XPA binding protein 2. (849 aa)
mnat1MNAT1 component of CDK activating kinase. (236 aa)
ENSSLDP00000006566BRCA2 DNA repair associated. (2740 aa)
ogg18-oxoguanine DNA glycosylase. (391 aa)
pold3Polymerase (DNA-directed), delta 3, accessory subunit. (444 aa)
ercc1Excision repair cross-complementation group 1. (357 aa)
pold1DNA polymerase. (1105 aa)
ENSSLDP00000008454PH_TFIIH domain-containing protein. (61 aa)
RAD23BRAD23 homolog B, nucleotide excision repair protein. (391 aa)
ENSSLDP00000020317General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (427 aa)
xpaXeroderma pigmentosum, complementation group A. (275 aa)
gtf2h3General transcription factor IIH, polypeptide 3. (278 aa)
fanccFA complementation group C. (586 aa)
sirt1Sirtuin 1. (696 aa)
gtf2h5General transcription factor IIH, polypeptide 5. (91 aa)
ercc2Excision repair cross-complementation group 2. (760 aa)
ercc8Excision repair cross-complementation group 8. (400 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (685 aa)
LOC111644662Centrin 4. (171 aa)
gtf2h1General transcription factor IIH, polypeptide 1. (550 aa)
rpa3Replication protein A3. (122 aa)
ENSSLDP00000029977Xeroderma pigmentosum, complementation group C. (795 aa)
ddb2Damage-specific DNA binding protein 2. (494 aa)
LOC111646515High mobility group nucleosomal binding domain 7. (96 aa)
poleDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2295 aa)
ercc4Excision repair cross-complementation group 4. (901 aa)
uvssaUV-stimulated scaffold protein A. (592 aa)
usp7Ubiquitin specific peptidase 7 (herpes virus-associated); Belongs to the peptidase C19 family. (998 aa)
ercc3Excision repair cross-complementation group 3. (803 aa)
LOC111652014Centrin, EF-hand protein, 2. (191 aa)
polr2iDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (126 aa)
LOC111647896General transcription factor IIH subunit. (392 aa)
pollPolymerase (DNA directed), lambda; Belongs to the DNA polymerase type-X family. (567 aa)
LOC111653873Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (600 aa)
hus1Checkpoint protein; Belongs to the HUS1 family. (285 aa)
LOC111671696Uncharacterized protein. (478 aa)
NTHL1Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family. (308 aa)
bivmBasic, immunoglobulin-like variable motif containing. (499 aa)
slx4SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae). (1512 aa)
ercc6Excision repair cross-complementation group 6. (1394 aa)
Your Current Organism:
Seriola lalandi
NCBI taxonomy Id: 1841481
Other names: S. lalandi dorsalis, Seriola dorsalis, Seriola lalandi dorsalis
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