(31 nodes) Motor neuron axon guidance network (Seriola lalandi)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	cdk5	Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
	LOC111644546	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (843 aa)
	nog	Noggin; Belongs to the noggin family. (227 aa)
	LOC111665592	RE1-silencing transcription factor. (955 aa)
	CDH2	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (848 aa)
	PPP1R12A	Protein phosphatase 1 regulatory subunit 12A. (563 aa)
	ENSSLDP00000024496	PRKG1_interact domain-containing protein. (165 aa)
	LOC111645152	Ring finger protein 165b. (362 aa)
	sema3a	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ab; Belongs to the semaphorin family. (806 aa)
	LOC111663819	Survival of motor neuron 1, telomeric. (284 aa)
	LOC111645184	NK2 homeobox 2b. (261 aa)
	tmem41b	Transmembrane protein 41B. (283 aa)
	LOC111665770	Netrin 5. (749 aa)
	ENSSLDP00000029363	ANK_REP_REGION domain-containing protein. (136 aa)
	LOC111671915	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Aa; Belongs to the semaphorin family. (862 aa)
	LOC111673809	Netrin 1b. (600 aa)
	NTN1	Netrin 1. (606 aa)
	LOC111657864	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fa; Belongs to the semaphorin family. (790 aa)
	LOC111656790	Ring finger protein 165a. (345 aa)
	chodl	Chondrolectin. (384 aa)
	e2f7	E2F transcription factor 7. (800 aa)
	ENSSLDP00000011488	Ras homolog gene family, member Gd. (117 aa)
	LOC111666651	Notum pectinacetylesterase 2. (518 aa)
	LOC111653190	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fb; Belongs to the semaphorin family. (678 aa)
	e2f8	E2F transcription factor 8. (869 aa)
	LOC111657503	NK2 homeobox 2a. (292 aa)
	LOC111664160	Vascular endothelial growth factor Aa; Belongs to the PDGF/VEGF growth factor family. (189 aa)
	lhx1	LIM homeobox 1a. (407 aa)
	LOC111658712	Netrin 2. (634 aa)
	LOC111649300	Ras homolog family member Gb. (180 aa)
	chst11	Carbohydrate sulfotransferase. (352 aa)

Your Current Organism:

Seriola lalandi

NCBI taxonomy Id: 1841481
Other names: S. lalandi dorsalis, Seriola dorsalis, Seriola lalandi dorsalis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDH2	LOC111644546	ENSSLDP00000024218	ENSSLDP00000020684	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.901
ENSSLDP00000011488	LOC111649300	ENSSLDP00000011488	ENSSLDP00000016282	Ras homolog gene family, member Gd.	Ras homolog family member Gb.	0.903
ENSSLDP00000024496	ENSSLDP00000029363	ENSSLDP00000024496	ENSSLDP00000029363	PRKG1_interact domain-containing protein.	ANK_REP_REGION domain-containing protein.	0.750
ENSSLDP00000024496	PPP1R12A	ENSSLDP00000024496	ENSSLDP00000024456	PRKG1_interact domain-containing protein.	Protein phosphatase 1 regulatory subunit 12A.	0.899
ENSSLDP00000029363	ENSSLDP00000024496	ENSSLDP00000029363	ENSSLDP00000024496	ANK_REP_REGION domain-containing protein.	PRKG1_interact domain-containing protein.	0.750
ENSSLDP00000029363	PPP1R12A	ENSSLDP00000029363	ENSSLDP00000024456	ANK_REP_REGION domain-containing protein.	Protein phosphatase 1 regulatory subunit 12A.	0.901
LOC111644546	CDH2	ENSSLDP00000020684	ENSSLDP00000024218	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins.	0.901
LOC111649300	ENSSLDP00000011488	ENSSLDP00000016282	ENSSLDP00000011488	Ras homolog family member Gb.	Ras homolog gene family, member Gd.	0.903
LOC111671915	cdk5	ENSSLDP00000030678	ENSSLDP00000017218	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Aa; Belongs to the semaphorin family.	Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily.	0.614
PPP1R12A	ENSSLDP00000024496	ENSSLDP00000024456	ENSSLDP00000024496	Protein phosphatase 1 regulatory subunit 12A.	PRKG1_interact domain-containing protein.	0.899
PPP1R12A	ENSSLDP00000029363	ENSSLDP00000024456	ENSSLDP00000029363	Protein phosphatase 1 regulatory subunit 12A.	ANK_REP_REGION domain-containing protein.	0.901
cdk5	LOC111671915	ENSSLDP00000017218	ENSSLDP00000030678	Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily.	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Aa; Belongs to the semaphorin family.	0.614
cdk5	sema3a	ENSSLDP00000017218	ENSSLDP00000025403	Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily.	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ab; Belongs to the semaphorin family.	0.614
chodl	tmem41b	ENSSLDP00000010183	ENSSLDP00000027591	Chondrolectin.	Transmembrane protein 41B.	0.581
e2f7	e2f8	ENSSLDP00000010991	ENSSLDP00000012639	E2F transcription factor 7.	E2F transcription factor 8.	0.655
e2f8	e2f7	ENSSLDP00000012639	ENSSLDP00000010991	E2F transcription factor 8.	E2F transcription factor 7.	0.655
sema3a	cdk5	ENSSLDP00000025403	ENSSLDP00000017218	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ab; Belongs to the semaphorin family.	Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily.	0.614
tmem41b	chodl	ENSSLDP00000027591	ENSSLDP00000010183	Transmembrane protein 41B.	Chondrolectin.	0.581