STRINGSTRING
slc37a4 slc37a4 plpp6 plpp6 wfs1 wfs1 LOC111655422 LOC111655422 LOC111666870 LOC111666870 LOC111655441 LOC111655441 elovl5 elovl5 ENSSLDP00000001524 ENSSLDP00000001524 Retreg1 Retreg1 dolk dolk LOC111656665 LOC111656665 insig2 insig2 tram2 tram2 LOC111669453 LOC111669453 atp13a1 atp13a1 slc37a1 slc37a1 edem1 edem1 zmpste24 zmpste24 LOC111659157 LOC111659157 LOC111656730 LOC111656730 rhbdd1 rhbdd1 LOC111656751 LOC111656751 fitm2 fitm2 ENSSLDP00000006146 ENSSLDP00000006146 TMEM33 TMEM33 tapt1 tapt1 LOC111663525 LOC111663525 LOC111672565 LOC111672565 slc35b3 slc35b3 acer3 acer3 ENSSLDP00000007282 ENSSLDP00000007282 ENSSLDP00000007824 ENSSLDP00000007824 LOC111661049 LOC111661049 tram1 tram1 LOC111647718 LOC111647718 pigu pigu LOC111666506 LOC111666506 ENSSLDP00000008806 ENSSLDP00000008806 LOC111667705 LOC111667705 slc37a3 slc37a3 LOC111661099 LOC111661099 MARCHF6 MARCHF6 LOC111657964 LOC111657964 emc4 emc4 hspa5 hspa5 spcs1 spcs1 LOC111658101 LOC111658101 xxylt1 xxylt1 dolpp1 dolpp1 sppl3 sppl3 ankle2 ankle2 LOC111652216 LOC111652216 atf6 atf6 LOC111656380 LOC111656380 pigs pigs camlg camlg emc10 emc10 LOC111656378 LOC111656378 ergic3 ergic3 LOC111644594 LOC111644594 ccdc47 ccdc47 fkbp8 fkbp8 wdr83os wdr83os slc35b1 slc35b1 LOC111654626 LOC111654626 LOC111645167 LOC111645167 Emc6 Emc6 LOC111645623 LOC111645623 emc8 emc8 Ktn1 Ktn1 tmco1 tmco1 atf6b atf6b saraf saraf SAMD8 SAMD8 elovl7 elovl7 tmem33 tmem33 emc9 emc9 LOC111654639 LOC111654639 LOC111653449 LOC111653449 derl2 derl2 insig1 insig1 LOC111652963 LOC111652963 LOC111671874 LOC111671874 dpm2 dpm2 selenos selenos pigg pigg aup1 aup1 emc7 emc7 pigk pigk elovl6 elovl6 sgms2 sgms2 Mboat4 Mboat4 mmgt1 mmgt1 LOC111666949 LOC111666949 emc1 emc1 lrit1 lrit1 porcn porcn slc35b2 slc35b2 LOC111670805 LOC111670805 LOC111664506 LOC111664506 LOC111645716 LOC111645716 pigt pigt zfyve27 zfyve27 sgms1 sgms1 LOC111672788 LOC111672788 LOC111655050 LOC111655050 ergic1 ergic1 DCSTAMP DCSTAMP LOC111673367 LOC111673367 hm13 hm13 preb preb LOC111671548 LOC111671548 tap1 tap1 slc35b4 slc35b4 sppl2b sppl2b sec62 sec62 cln3 cln3 emc2 emc2 LOC111667962 LOC111667962 LOC111654473 LOC111654473 LOC111661197 LOC111661197 LOC111672877 LOC111672877 LOC111669805 LOC111669805 derl1 derl1 abcb9 abcb9 dhcr7 dhcr7 ENSSLDP00000017846 ENSSLDP00000017846 hacd4 hacd4 dpm3 dpm3 LOC111658153 LOC111658153 slc37a2 slc37a2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
slc37a4Solute carrier family 37 member 4a. (429 aa)
plpp6Phospholipid phosphatase 6. (286 aa)
wfs1Wolfram syndrome 1b (wolframin). (975 aa)
LOC111655422Transporter associated with antigen processing, subunit type t, teleost specific. (713 aa)
LOC111666870Peptidylprolyl isomerase. (478 aa)
LOC111655441Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...] (269 aa)
elovl5Elongation of very long chain fatty acids protein 5; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involv [...] (294 aa)
ENSSLDP00000001524Uncharacterized protein; Belongs to the heat shock protein 70 family. (624 aa)
Retreg1Reticulophagy regulator 1. (360 aa)
dolkDolichol kinase. (523 aa)
LOC111656665Zgc:162183. (432 aa)
insig2Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (235 aa)
tram2Translocating chain-associated membrane protein; Belongs to the TRAM family. (371 aa)
LOC111669453Ribosome binding protein 1a. (1119 aa)
atp13a1Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1196 aa)
slc37a1Solute carrier family 37 member 1. (544 aa)
edem1alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (638 aa)
zmpste24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (467 aa)
LOC111659157Uncharacterized protein. (468 aa)
LOC111656730Transmembrane anterior posterior transformation 1a. (533 aa)
rhbdd1Rhomboid domain containing 1. (323 aa)
LOC111656751Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...] (273 aa)
fitm2Fat storage inducing transmembrane protein 2. (258 aa)
ENSSLDP00000006146Elongation of very long chain fatty acids protein. (147 aa)
TMEM33Transmembrane protein 33. (110 aa)
tapt1Transmembrane anterior posterior transformation 1b. (572 aa)
LOC111663525Solute carrier family 37 member 4b. (450 aa)
LOC111672565Uncharacterized protein; Belongs to the glycosyltransferase 47 family. (776 aa)
slc35b3Solute carrier family 35 member B3. (374 aa)
acer3Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (282 aa)
ENSSLDP00000007282Uncharacterized protein. (92 aa)
ENSSLDP00000007824Uncharacterized protein. (232 aa)
LOC111661049PAP2_C domain-containing protein. (384 aa)
tram1Translocating chain-associated membrane protein; Belongs to the TRAM family. (370 aa)
LOC111647718Uncharacterized protein. (237 aa)
piguPhosphatidylinositol glycan anchor biosynthesis, class U. (435 aa)
LOC111666506acidPPc domain-containing protein. (243 aa)
ENSSLDP00000008806Uncharacterized protein. (248 aa)
LOC111667705Transmembrane protein 33-like. (96 aa)
slc37a3MFS domain-containing protein. (502 aa)
LOC111661099Glycosylphosphatidylinositol anchor attachment 1. (522 aa)
MARCHF6Membrane associated ring-CH-type finger 6. (915 aa)
LOC111657964Rhomboid domain-containing protein. (304 aa)
emc4ER membrane protein complex subunit 4; Belongs to the EMC4 family. (190 aa)
hspa5Heat shock protein 5; Belongs to the heat shock protein 70 family. (654 aa)
spcs1Signal peptidase complex subunit 1. (143 aa)
LOC111658101Uncharacterized protein; Belongs to the glycosyltransferase 47 family. (743 aa)
xxylt1Xyloside xylosyltransferase 1. (405 aa)
dolpp1Dolichyldiphosphatase 1. (238 aa)
sppl3Signal peptide peptidase 3. (383 aa)
ankle2Ankyrin repeat and LEM domain containing 2. (976 aa)
LOC111652216ER membrane protein complex subunit 3; Belongs to the EMC3 family. (261 aa)
atf6Activating transcription factor 6. (645 aa)
LOC111656380Elongation of very long chain fatty acids protein 1; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that [...] (335 aa)
pigsPhosphatidylinositol glycan anchor biosynthesis, class S. (562 aa)
camlgCalcium signal-modulating cyclophilin ligand; Likely involved in the mobilization of calcium as a result of the TCR/CD3 complex interaction. Binds to cyclophilin B. (289 aa)
emc10ER membrane protein complex subunit 10. (256 aa)
LOC111656378Elongation of very long chain fatty acids protein. (280 aa)
ergic3ERGIC and golgi 3. (384 aa)
LOC111644594Lunapark, ER junction formation factor. (452 aa)
ccdc47Coiled-coil domain containing 47. (488 aa)
fkbp8Peptidylprolyl isomerase. (405 aa)
wdr83osWD repeat domain 83 opposite strand. (106 aa)
slc35b1Solute carrier family 35 member B1. (330 aa)
LOC111654626Limb and neural patterns a. (405 aa)
LOC111645167cAMP responsive element binding protein 3-like 3 like. (498 aa)
Emc6ER membrane protein complex subunit 6. (113 aa)
LOC111645623TAP binding protein (tapasin), tandem duplicate 2. (430 aa)
emc8ER membrane protein complex subunit 8. (204 aa)
Ktn1Uncharacterized protein. (258 aa)
tmco1Calcium load-activated calcium channel; Calcium-selective channel required to prevent calcium stores from overfilling. (188 aa)
atf6bBZIP domain-containing protein. (733 aa)
sarafStore-operated calcium entry-associated regulatory factor. (385 aa)
SAMD8Sterile alpha motif domain containing 8. (408 aa)
elovl7Elongation of very long chain fatty acids protein 7; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0 [...] (294 aa)
tmem33Transmembrane protein 33. (229 aa)
emc9ER membrane protein complex subunit 9. (205 aa)
LOC111654639Leucine-rich repeat, immunoglobulin-like and transmembrane domains 1a. (651 aa)
LOC111653449Elongation of very long chain fatty acids protein. (257 aa)
derl2Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (239 aa)
insig1Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. (276 aa)
LOC111652963RING-CH-type domain-containing protein. (864 aa)
LOC111671874Exostosin glycosyltransferase 1b; Belongs to the glycosyltransferase 47 family. (649 aa)
dpm2Dolichol phosphate-mannose biosynthesis regulatory protein; Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization. Belongs to the DPM2 family. (83 aa)
selenosSelenoprotein S. (192 aa)
piggPhosphatidylinositol glycan anchor biosynthesis class G. (968 aa)
aup1AUP1 lipid droplet regulating VLDL assembly factor. (415 aa)
emc7ER membrane protein complex subunit 7. (249 aa)
pigkGPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family. (383 aa)
elovl6Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...] (268 aa)
sgms2Sphingomyelin synthase 2a. (357 aa)
Mboat4Membrane bound O-acyltransferase domain containing 4; Belongs to the membrane-bound acyltransferase family. (436 aa)
mmgt1Membrane magnesium transporter 1. (184 aa)
LOC111666949Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (357 aa)
emc1ER membrane protein complex subunit 1. (962 aa)
lrit1Leucine-rich repeat, immunoglobulin-like and transmembrane domains 1b. (651 aa)
porcnPorcupine O-acyltransferase; Belongs to the membrane-bound acyltransferase family. (450 aa)
slc35b2Solute carrier family 35 member B2. (433 aa)
LOC111670805Uncharacterized protein; Belongs to the membrane-bound acyltransferase family. (447 aa)
LOC111664506Wolfram syndrome 1a (wolframin). (1054 aa)
LOC111645716Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (243 aa)
pigtPhosphatidylinositol glycan anchor biosynthesis, class T. (476 aa)
zfyve27Zinc finger, FYVE domain containing 27. (438 aa)
sgms1Zgc:91976. (412 aa)
LOC111672788Elongation of very long chain fatty acids protein 4; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane [...] (305 aa)
LOC111655050Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (361 aa)
ergic1Endoplasmic reticulum-golgi intermediate compartment 1. (301 aa)
DCSTAMPDendrocyte expressed seven transmembrane protein. (459 aa)
LOC111673367ER membrane protein complex subunit 3; Belongs to the EMC3 family. (261 aa)
hm13Histocompatibility (minor) 13. (395 aa)
prebProlactin regulatory element binding. (432 aa)
LOC111671548Translocating chain-associated membrane protein; Belongs to the TRAM family. (371 aa)
tap1Transporter 1, ATP-binding cassette, sub-family B (MDR/TAP). (741 aa)
slc35b4Solute carrier family 35 member B4. (332 aa)
sppl2bSignal peptide peptidase-like 2. (558 aa)
sec62SEC62 homolog, preprotein translocation factor. (403 aa)
cln3Battenin. (442 aa)
emc2ER membrane protein complex subunit 2. (297 aa)
LOC111667962Ras converting CAAX endopeptidase 1a. (301 aa)
LOC111654473Elongation of very long chain fatty acids protein 1; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that [...] (314 aa)
LOC111661197Transporter associated with antigen processing, subunit type a. (718 aa)
LOC111672877Ribosome binding protein 1b. (633 aa)
LOC111669805Fat storage inducing transmembrane protein 1, like. (285 aa)
derl1Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (258 aa)
abcb9Uncharacterized protein. (813 aa)
dhcr77-dehydrocholesterol reductase. (478 aa)
ENSSLDP00000017846Uncharacterized protein. (193 aa)
hacd4Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (214 aa)
dpm3Dolichol-phosphate mannosyltransferase subunit 3; Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER. Belongs to the DPM3 family. (92 aa)
LOC111658153Elongation of very long chain fatty acids protein 4; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane [...] (319 aa)
slc37a2Solute carrier family 37 member 2. (499 aa)
Your Current Organism:
Seriola lalandi
NCBI taxonomy Id: 1841481
Other names: S. lalandi dorsalis, Seriola dorsalis, Seriola lalandi dorsalis
Server load: low (16%) [HD]