STRINGSTRING
sirt1 sirt1 srebf1 srebf1 GABARAPL2 GABARAPL2 eif2s1 eif2s1 ENSSLDP00000032339 ENSSLDP00000032339 ENSSLDP00000032378 ENSSLDP00000032378 ENSSLDP00000032389 ENSSLDP00000032389 ENSSLDP00000032400 ENSSLDP00000032400 ENSSLDP00000032423 ENSSLDP00000032423 GCG GCG pick1 pick1 prkag1 prkag1 rnf152 rnf152 LOC111672757 LOC111672757 LOC111668965 LOC111668965 LOC111670053 LOC111670053 tbc1d5 tbc1d5 LOC111673566 LOC111673566 LOC111672528 LOC111672528 LOC111671363 LOC111671363 rrp8 rrp8 ENSSLDP00000001050 ENSSLDP00000001050 bmt2 bmt2 LOC111654296 LOC111654296 ENSSLDP00000001524 ENSSLDP00000001524 LOC111653033 LOC111653033 gas6 gas6 rptor rptor WIPI1 WIPI1 wdr59 wdr59 rragc rragc lamp2 lamp2 ttc5 ttc5 LOC111651868 LOC111651868 bnip1 bnip1 LOC111664655 LOC111664655 eif2ak1 eif2ak1 LOC111661631 LOC111661631 LOC111647741 LOC111647741 ENSSLDP00000004866 ENSSLDP00000004866 fbxo22 fbxo22 bhlha15 bhlha15 mtor mtor atg7 atg7 EIF2AK4 EIF2AK4 itfg2 itfg2 LOC111649210 LOC111649210 ENSSLDP00000006834 ENSSLDP00000006834 pik3c3 pik3c3 gnpat gnpat ddit3 ddit3 DAPL1 DAPL1 LOC111655524 LOC111655524 ENSSLDP00000007753 ENSSLDP00000007753 LOC111650214 LOC111650214 BCL2 BCL2 ENSSLDP00000008166 ENSSLDP00000008166 LOC111660568 LOC111660568 fnip1 fnip1 LOC111648212 LOC111648212 kptn kptn LOC111670232 LOC111670232 ENSSLDP00000008760 ENSSLDP00000008760 acadm acadm lars1 lars1 LOC111667758 LOC111667758 LOC111644331 LOC111644331 atf3 atf3 LOC111649950 LOC111649950 LOC111667813 LOC111667813 ENSSLDP00000009789 ENSSLDP00000009789 ENSSLDP00000009840 ENSSLDP00000009840 LOC111648137 LOC111648137 LOC111667237 LOC111667237 LOC111669043 LOC111669043 LOC111669158 LOC111669158 hspa5 hspa5 impact impact pik3r4 pik3r4 nprl2 nprl2 ENSSLDP00000011584 ENSSLDP00000011584 LOC111669122 LOC111669122 ENSSLDP00000011706 ENSSLDP00000011706 LOC111659265 LOC111659265 depdc5 depdc5 lrrk2 lrrk2 WHAMM WHAMM LOC111648378 LOC111648378 gabarap gabarap ATG14 ATG14 LOC111655639 LOC111655639 LOC111658718 LOC111658718 ulk2 ulk2 Nprl3 Nprl3 dap dap ENSSLDP00000014146 ENSSLDP00000014146 ppm1d ppm1d seh1l seh1l MAP1LC3A MAP1LC3A bcas3 bcas3 LOC111666039 LOC111666039 Szt2 Szt2 SZT2 SZT2 LOC111645537 LOC111645537 LOC111661773 LOC111661773 LOC111644420 LOC111644420 eif2ak3 eif2ak3 wdr24 wdr24 pck1 pck1 gcn1 gcn1 atg5 atg5 LOC111655733 LOC111655733 LOC111645045 LOC111645045 JMY JMY LOC111654033 LOC111654033 xbp1 xbp1 tbl2 tbl2 prkaa1 prkaa1 mios mios LOC111662411 LOC111662411 LOC111669346 LOC111669346 LOC111655832 LOC111655832 cunh12orf66 cunh12orf66 clec16a clec16a LOC111663951 LOC111663951 LOC111665039 LOC111665039 becn1 becn1 LOC111652289 LOC111652289 wdr45b wdr45b nim1k nim1k nfe2l2 nfe2l2 LOC111662132 LOC111662132 bcl2 bcl2 LOC111670476 LOC111670476 sesn1 sesn1 wipi2 wipi2 LOC111646360 LOC111646360 LOC111645172 LOC111645172 bmpr2 bmpr2 LOC111671828 LOC111671828 LOC111671813 LOC111671813 sik2 sik2 ZFYVE1 ZFYVE1 ENSSLDP00000028517 ENSSLDP00000028517 flcn flcn foxk1 foxk1 wdr45 wdr45 LOC111660789 LOC111660789 pcsk9 pcsk9 nuak1 nuak1 LOC111673153 LOC111673153 vps41 vps41
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
sirt1Sirtuin 1. (696 aa)
srebf1Sterol regulatory element binding transcription factor 1. (1198 aa)
GABARAPL2GABA type A receptor associated protein like 2. (132 aa)
eif2s1Eukaryotic translation initiation factor 2, subunit 1 alpha b. (315 aa)
ENSSLDP00000032339Uncharacterized protein. (152 aa)
ENSSLDP00000032378Uncharacterized protein; Belongs to the protein kinase superfamily. (472 aa)
ENSSLDP00000032389Eukaryotic translation initiation factor 2-alpha kinase 2. (700 aa)
ENSSLDP00000032400Eukaryotic translation initiation factor 2-alpha kinase 2. (665 aa)
ENSSLDP00000032423Eukaryotic translation initiation factor 2-alpha kinase 2. (701 aa)
GCGGlucagon. (177 aa)
pick1Protein interacting with prkca 1. (416 aa)
prkag1Protein kinase, AMP-activated, gamma 1 non-catalytic subunit. (336 aa)
rnf152Ring finger protein 152. (168 aa)
LOC111672757Si:ch73-21k16.5; Belongs to the GPAT/DAPAT family. (676 aa)
LOC111668965Si:ch211-117c9.1. (711 aa)
LOC111670053Uncharacterized protein. (321 aa)
tbc1d5TBC1 domain family, member 5. (789 aa)
LOC111673566Protein kinase domain-containing protein. (101 aa)
LOC111672528Zinc finger, FYVE domain containing 1. (779 aa)
LOC111671363Si:ch211-11n16.2. (655 aa)
rrp8Ribosomal RNA-processing protein 8; Probable methyltransferase required to silence rDNA. Belongs to the methyltransferase superfamily. RRP8 family. (558 aa)
ENSSLDP00000001050CBM21 domain-containing protein. (313 aa)
bmt2S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...] (392 aa)
LOC111654296Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (395 aa)
ENSSLDP00000001524Uncharacterized protein; Belongs to the heat shock protein 70 family. (624 aa)
LOC111653033Si:ch211-153j24.3. (403 aa)
gas6Growth arrest-specific 6. (616 aa)
rptorRegulatory associated protein of MTOR, complex 1. (1270 aa)
WIPI1WD repeat domain, phosphoinositide interacting 1. (440 aa)
wdr59WD repeat domain 59. (973 aa)
rragcRas-related GTP binding Ca. (382 aa)
lamp2Lysosomal-associated membrane protein 2. (426 aa)
ttc5Tetratricopeptide repeat domain 5. (444 aa)
LOC111651868SPX domain-containing protein. (385 aa)
bnip1BCL2 interacting protein 1a. (228 aa)
LOC111664655Cytoplasmic polyadenylation element binding protein 4a. (323 aa)
eif2ak1Eukaryotic translation initiation factor 2-alpha kinase 1. (662 aa)
LOC111661631Zinc finger CCCH-type containing 12A. (625 aa)
LOC111647741GABA(A) receptor-associated protein like 2. (126 aa)
ENSSLDP00000004866Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
fbxo22F-box protein 22. (387 aa)
bhlha15Basic helix-loop-helix family, member a15. (189 aa)
mtorSerine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2494 aa)
atg7ATG7 autophagy related 7 homolog (S. cerevisiae). (720 aa)
EIF2AK4Eukaryotic translation initiation factor 2 alpha kinase 4. (1541 aa)
itfg2Integrin alpha FG-GAP repeat containing 2. (474 aa)
LOC111649210Uncharacterized protein. (121 aa)
ENSSLDP00000006834Uncharacterized protein. (117 aa)
pik3c3Phosphatidylinositol 3-kinase catalytic subunit type 3. (884 aa)
gnpatGlyceronephosphate O-acyltransferase; Belongs to the GPAT/DAPAT family. (686 aa)
ddit3DNA-damage-inducible transcript 3. (312 aa)
DAPL1Death associated protein 1b. (116 aa)
LOC111655524Uncharacterized protein. (614 aa)
ENSSLDP00000007753Uncharacterized protein. (102 aa)
LOC111650214Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (296 aa)
BCL2BCL2 apoptosis regulator. (212 aa)
ENSSLDP00000008166Hypocretin (orexin) neuropeptide precursor. (118 aa)
LOC111660568Phosphoinositide phospholipase C. (1210 aa)
fnip1Folliculin interacting protein 1. (1093 aa)
LOC111648212Phosphoenolpyruvate carboxykinase 2 (mitochondrial). (682 aa)
kptnKaptin (actin binding protein). (439 aa)
LOC111670232Microtubule-associated protein 1 light chain 3 gamma. (128 aa)
ENSSLDP00000008760Reverse transcriptase domain-containing protein. (374 aa)
acadmAcyl-CoA dehydrogenase medium chain. (424 aa)
lars1Leucyl-tRNA synthetase b; Belongs to the class-I aminoacyl-tRNA synthetase family. (1184 aa)
LOC111667758Transcription factor EB. (513 aa)
LOC111644331Uncharacterized protein. (630 aa)
atf3Activating transcription factor 3. (226 aa)
LOC111649950Non-specific serine/threonine protein kinase. (556 aa)
LOC111667813RWD domain-containing protein. (113 aa)
ENSSLDP00000009789Uncharacterized protein. (504 aa)
ENSSLDP00000009840Uncharacterized protein. (127 aa)
LOC1116481375'-AMP-activated protein kinase, regulatory gamma subunit. (133 aa)
LOC111667237WD repeat domain, phosphoinositide interacting 1. (429 aa)
LOC111669043Uncharacterized protein. (435 aa)
LOC111669158CobW C-terminal domain-containing protein. (416 aa)
hspa5Heat shock protein 5; Belongs to the heat shock protein 70 family. (654 aa)
impactImpact RWD domain protein. (317 aa)
pik3r4Phosphoinositide-3-kinase, regulatory subunit 4. (1281 aa)
nprl2NPR2 like, GATOR1 complex subunit. (227 aa)
ENSSLDP00000011584Uncharacterized protein. (70 aa)
LOC111669122Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (429 aa)
ENSSLDP00000011706Si:dkey-206d17.12. (274 aa)
LOC111659265Sestrin 2. (556 aa)
depdc5DEP domain containing 5. (1524 aa)
lrrk2Leucine-rich repeat kinase 2. (2341 aa)
WHAMMWASP homolog associated with actin, golgi membranes and microtubules. (894 aa)
LOC111648378Xenotropic and polytropic retrovirus receptor 1b. (610 aa)
gabarapGABA(A) receptor-associated protein b. (122 aa)
ATG14Autophagy related 14. (472 aa)
LOC111655639Unc-51 like autophagy activating kinase 1. (955 aa)
LOC111658718Protein kinase domain-containing protein. (748 aa)
ulk2Unc-51 like autophagy activating kinase 2. (1042 aa)
Nprl3NPR3-like, GATOR1 complex subunit. (232 aa)
dapDeath-associated protein. (104 aa)
ENSSLDP00000014146Uncharacterized protein. (113 aa)
ppm1dProtein phosphatase, Mg2+/Mn2+ dependent, 1Da. (568 aa)
seh1lSEH1-like (S. cerevisiae); Belongs to the WD repeat SEC13 family. (415 aa)
MAP1LC3AMicrotubule-associated protein 1 light chain 3 alpha. (121 aa)
bcas3BCAS3 microtubule associated cell migration factor. (915 aa)
LOC111666039Autophagy/beclin-1 regulator 1b. (1381 aa)
Szt2Uncharacterized protein. (104 aa)
SZT2SZT2 subunit of KICSTOR complex. (2377 aa)
LOC111645537Ras-related GTP binding D. (393 aa)
LOC111661773Protein kinase domain-containing protein. (666 aa)
LOC111644420Protein kinase, AMP-activated, gamma 3a non-catalytic subunit. (336 aa)
eif2ak3Eukaryotic translation initiation factor 2-alpha kinase 3. (1107 aa)
wdr24WD repeat domain 24. (789 aa)
pck1Phosphoenolpyruvate carboxykinase 1 (soluble). (624 aa)
gcn1GCN1 activator of EIF2AK4. (2671 aa)
atg5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
LOC111655733Microtubule-associated protein 1 light chain 3 beta. (125 aa)
LOC111645045Unc-51 like autophagy activating kinase 1a. (919 aa)
JMYJunction mediating and regulatory protein, p53 cofactor. (899 aa)
LOC111654033Ras-related GTP binding A. (315 aa)
xbp1X-box binding protein 1. (297 aa)
tbl2Transducin (beta)-like 2. (441 aa)
prkaa1Non-specific serine/threonine protein kinase. (573 aa)
miosMissing oocyte, meiosis regulator, homolog (Drosophila). (875 aa)
LOC111662411Si:dkey-16p21.7. (707 aa)
LOC111669346Si:ch211-22d5.2; Belongs to the protein kinase superfamily. (433 aa)
LOC111655832Si:zfos-80g12.1. (444 aa)
cunh12orf66Si:ch211-125a15.1. (449 aa)
clec16aC-type lectin domain containing 16A. (999 aa)
LOC111663951Protein phosphatase, Mg2+/Mn2+ dependent, 1Db. (574 aa)
LOC111665039Protein kinase domain-containing protein. (108 aa)
becn1Beclin 1, autophagy related. (447 aa)
LOC111652289Forkhead box K2. (618 aa)
wdr45bWD repeat domain 45B. (344 aa)
nim1kNIM1 serine/threonine protein kinase; Belongs to the protein kinase superfamily. (475 aa)
nfe2l2Nuclear factor, erythroid 2-like 2a. (612 aa)
LOC111662132Salt-inducible kinase 1. (805 aa)
bcl2BCL2 apoptosis regulator b. (228 aa)
LOC111670476Protein kinase, AMP-activated, gamma 2 non-catalytic subunit b. (441 aa)
sesn1Sestrin 1. (547 aa)
wipi2WD repeat domain, phosphoinositide interacting 2. (425 aa)
LOC111646360Activating transcription factor 4b. (457 aa)
LOC111645172COBW domain containing. (430 aa)
bmpr2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1068 aa)
LOC111671828Activating transcription factor 4a. (464 aa)
LOC111671813Uncharacterized protein. (382 aa)
sik2Salt-inducible kinase 2b. (863 aa)
ZFYVE1Zinc finger FYVE-type containing 1. (786 aa)
ENSSLDP00000028517Uncharacterized protein. (164 aa)
flcnFolliculin. (559 aa)
foxk1Forkhead box K1. (634 aa)
wdr45WD repeat domain 45. (358 aa)
LOC111660789NUAK family, SNF1-like kinase, 2. (627 aa)
pcsk9Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family. (729 aa)
nuak1NUAK family, SNF1-like kinase, 1b. (661 aa)
LOC111673153Protein kinase, AMP-activated, gamma 3b non-catalytic subunit. (331 aa)
vps41Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family. (853 aa)
Your Current Organism:
Seriola lalandi
NCBI taxonomy Id: 1841481
Other names: S. lalandi dorsalis, Seriola dorsalis, Seriola lalandi dorsalis
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