97 items (Seriola lalandi) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC111655270	USP domain-containing protein; Belongs to the peptidase C19 family. (220 aa)
	ndufs3	NADH:ubiquinone oxidoreductase core subunit S3; Belongs to the complex I 30 kDa subunit family. (261 aa)
	ptpmt1	Protein tyrosine phosphatase mitochondrial 1. (182 aa)
	ivns1abp	Influenza virus NS1A binding protein a. (650 aa)
	pdx1	Pancreatic and duodenal homeobox 1. (248 aa)
	ptgs2	Prostaglandin-endoperoxide synthase 2b. (642 aa)
	LOC111644184	Tyrosine-protein kinase. (550 aa)
	nme5	NME/NM23 family member 5; Belongs to the NDK family. (211 aa)
	ddias	Rep_fac-A_C domain-containing protein. (852 aa)
	LOC111659119	Uncharacterized protein. (949 aa)
	ddit3	DNA-damage-inducible transcript 3. (312 aa)
	vax2	Ventral anterior homeobox 2. (306 aa)
	nck2	Cytoplasmic protein. (398 aa)
	ENSSLDP00000008060	Gasdermin domain-containing protein. (298 aa)
	BCL2	BCL2 apoptosis regulator. (212 aa)
	BDKRB2	Bradykinin receptor B2; Belongs to the G-protein coupled receptor 1 family. (352 aa)
	Triap1	TP53 regulated inhibitor of apoptosis 1. (84 aa)
	trim32	Tripartite motif containing 32. (626 aa)
	LOC111661696	Uncharacterized protein. (898 aa)
	LOC111661685	Receptor-interacting serine-threonine kinase 3. (512 aa)
	ENSSLDP00000011023	Uncharacterized protein. (90 aa)
	atad5	ATPase family AAA domain containing 5a. (1693 aa)
	bad	BCL2 associated agonist of cell death b. (167 aa)
	wfs1	Wolfram syndrome 1b (wolframin). (975 aa)
	fam167a	Family with sequence similarity 167 member Ab. (209 aa)
	prkn	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (449 aa)
	noc2l	NOC2-like nucleolar associated transcriptional repressor. (754 aa)
	LOC111659102	BCL2 like 10. (190 aa)
	ENSSLDP00000031244	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (95 aa)
	LOC111664506	Wolfram syndrome 1a (wolframin). (1054 aa)
	LOC111672783	Uncharacterized protein. (661 aa)
	LOC111653167	Clusterin; Belongs to the clusterin family. (504 aa)
	marchf7	RING-CH-type domain-containing protein. (800 aa)
	ENSSLDP00000011576	Pyrin domain-containing protein. (197 aa)
	bax	BCL2 associated X, apoptosis regulator a. (192 aa)
	LOC111669704	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (360 aa)
	LOC111660747	Nuclear protein 1b. (74 aa)
	lrrk2	Leucine-rich repeat kinase 2. (2341 aa)
	uri1	URI1 prefoldin like chaperone. (506 aa)
	bcl2l12	Si:ch73-248e21.1. (344 aa)
	ENSSLDP00000013246	Uncharacterized protein. (140 aa)
	rnf2	Ring finger protein 2. (342 aa)
	NDUFA13	NADH:ubiquinone oxidoreductase subunit A13. (144 aa)
	skil	SKI-like proto-oncogene a. (770 aa)
	LOC111649240	Cylindromatosis (turban tumor syndrome), b. (710 aa)
	ptpn2	Tyrosine-protein phosphatase non-receptor type. (415 aa)
	usp47	Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family. (1365 aa)
	LOC111649248	BH4_2 domain-containing protein. (221 aa)
	LOC111669791	Nuclear protein 1-like. (74 aa)
	LOC111664767	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (204 aa)
	snai2	Snail family zinc finger 2. (260 aa)
	hyou1	Hypoxia up-regulated 1. (981 aa)
	LOC111669226	MCL1 apoptosis regulator, BCL2 family member b. (285 aa)
	eif2ak3	Eukaryotic translation initiation factor 2-alpha kinase 3. (1107 aa)
	ptpn1	Tyrosine-protein phosphatase non-receptor type. (437 aa)
	LOC111659360	Tyrosine-protein phosphatase non-receptor type. (394 aa)
	bag5	BCL2 associated athanogene 5. (486 aa)
	fbh1	F-box DNA helicase 1. (881 aa)
	ENSSLDP00000018864	UPAR/Ly6 domain-containing protein. (170 aa)
	LOC111671691	UPAR/Ly6 domain-containing protein. (166 aa)
	nck1	Cytoplasmic protein. (393 aa)
	xbp1	X-box binding protein 1. (297 aa)
	gsdme	Gasdermin Eb. (465 aa)
	LOC111665015	Neuromast-expressed gpi-anchored lymphocyte antigen 6. (194 aa)
	bcl2l1	BCL2 like 1. (232 aa)
	LOC111658180	Muscle segment homeobox 3. (255 aa)
	LOC111671564	Cylindromatosis (turban tumor syndrome), like. (657 aa)
	ENSSLDP00000021278	ATPase family AAA domain containing 5b. (887 aa)
	pink1	PTEN induced kinase 1. (575 aa)
	cyld	Cylindromatosis (turban tumor syndrome), a; Belongs to the peptidase C19 family. (956 aa)
	vax1	Ventral anterior homeobox 1. (313 aa)
	hells	Helicase, lymphoid specific. (853 aa)
	LOC111645167	cAMP responsive element binding protein 3-like 3 like. (498 aa)
	nfe2l2	Nuclear factor, erythroid 2-like 2a. (612 aa)
	msx1	Muscle segment homeobox 1a. (320 aa)
	styxl1	Serine/threonine/tyrosine interacting-like 1. (295 aa)
	ENSSLDP00000025074	Nuclear protein 1a. (75 aa)
	bcl2	BCL2 apoptosis regulator b. (228 aa)
	kdm1a	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (855 aa)
	sirt1	Sirtuin 1. (696 aa)
	hspb1	Heat shock protein, alpha-crystallin-related, 1; Belongs to the small heat shock protein (HSP20) family. (209 aa)
	RING1	Ring finger protein 1. (409 aa)
	ENSSLDP00000026099	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (286 aa)
	src	Tyrosine-protein kinase. (550 aa)
	LOC111662181	Atypical chemokine receptor 3a; Belongs to the G-protein coupled receptor 1 family. (378 aa)
	CLUL1	Clusterin; Belongs to the clusterin family. (475 aa)
	LOC111663963	NK3 homeobox 1. (197 aa)
	LOC111645255	Si:dkey-63b1.1; Belongs to the G-protein coupled receptor 1 family. (357 aa)
	ENSSLDP00000028517	Uncharacterized protein. (164 aa)
	ENSSLDP00000028655	Pyrin domain-containing protein. (144 aa)
	trap1	TNF receptor-associated protein 1. (721 aa)
	flcn	Folliculin. (559 aa)
	ENSSLDP00000029029	Tumor protein, translationally-controlled 1; Belongs to the TCTP family. (169 aa)
	clu	Clusterin; Belongs to the clusterin family. (468 aa)
	txndc12	Thioredoxin domain containing 12 (endoplasmic reticulum). (173 aa)
	cdkn2d	Cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4). (188 aa)
	tmem161a	Transmembrane protein 161A. (496 aa)

Your Current Organism:

Seriola lalandi

NCBI taxonomy Id: 1841481
Other names: S. lalandi dorsalis, Seriola dorsalis, Seriola lalandi dorsalis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BCL2	ENSSLDP00000028517	ENSSLDP00000008110	ENSSLDP00000028517	BCL2 apoptosis regulator.	Uncharacterized protein.	0.900
BCL2	LOC111649248	ENSSLDP00000008110	ENSSLDP00000014458	BCL2 apoptosis regulator.	BH4_2 domain-containing protein.	0.696
BCL2	LOC111659102	ENSSLDP00000008110	ENSSLDP00000003000	BCL2 apoptosis regulator.	BCL2 like 10.	0.443
BCL2	LOC111669226	ENSSLDP00000008110	ENSSLDP00000016687	BCL2 apoptosis regulator.	MCL1 apoptosis regulator, BCL2 family member b.	0.424
BCL2	bad	ENSSLDP00000008110	ENSSLDP00000000275	BCL2 apoptosis regulator.	BCL2 associated agonist of cell death b.	0.986
BCL2	bax	ENSSLDP00000008110	ENSSLDP00000011631	BCL2 apoptosis regulator.	BCL2 associated X, apoptosis regulator a.	0.989
BCL2	bcl2	ENSSLDP00000008110	ENSSLDP00000025101	BCL2 apoptosis regulator.	BCL2 apoptosis regulator b.	0.900
BCL2	bcl2l1	ENSSLDP00000008110	ENSSLDP00000020252	BCL2 apoptosis regulator.	BCL2 like 1.	0.684
BCL2	ddit3	ENSSLDP00000008110	ENSSLDP00000007047	BCL2 apoptosis regulator.	DNA-damage-inducible transcript 3.	0.930
ENSSLDP00000008060	flcn	ENSSLDP00000008060	ENSSLDP00000028959	Gasdermin domain-containing protein.	Folliculin.	0.408
ENSSLDP00000011023	ENSSLDP00000021278	ENSSLDP00000011023	ENSSLDP00000021278	Uncharacterized protein.	ATPase family AAA domain containing 5b.	0.471
ENSSLDP00000011023	atad5	ENSSLDP00000011023	ENSSLDP00000033500	Uncharacterized protein.	ATPase family AAA domain containing 5a.	0.471
ENSSLDP00000021278	ENSSLDP00000011023	ENSSLDP00000021278	ENSSLDP00000011023	ATPase family AAA domain containing 5b.	Uncharacterized protein.	0.471
ENSSLDP00000021278	fbh1	ENSSLDP00000021278	ENSSLDP00000018310	ATPase family AAA domain containing 5b.	F-box DNA helicase 1.	0.672
ENSSLDP00000021278	hells	ENSSLDP00000021278	ENSSLDP00000024344	ATPase family AAA domain containing 5b.	Helicase, lymphoid specific.	0.471
ENSSLDP00000026099	LOC111649240	ENSSLDP00000026099	ENSSLDP00000014319	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Cylindromatosis (turban tumor syndrome), b.	0.460
ENSSLDP00000026099	LOC111661696	ENSSLDP00000026099	ENSSLDP00000010860	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.446
ENSSLDP00000026099	LOC111671564	ENSSLDP00000026099	ENSSLDP00000020720	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Cylindromatosis (turban tumor syndrome), like.	0.460
ENSSLDP00000026099	cyld	ENSSLDP00000026099	ENSSLDP00000022564	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Cylindromatosis (turban tumor syndrome), a; Belongs to the peptidase C19 family.	0.460
ENSSLDP00000026099	prkn	ENSSLDP00000026099	ENSSLDP00000001635	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.681