36 items (Seriola lalandi) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	gtf2f1	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (516 aa)
	ccnh	Cyclin H; Belongs to the cyclin family. (319 aa)
	gtf2h3	General transcription factor IIH, polypeptide 3. (278 aa)
	supt4h1	Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family. (117 aa)
	gtf2h5	General transcription factor IIH, polypeptide 5. (91 aa)
	ercc2	Excision repair cross-complementation group 2. (760 aa)
	ncbp2	Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (199 aa)
	polr2a	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1966 aa)
	LOC111652781	Si:dkey-12j5.1. (316 aa)
	ENSSLDP00000020317	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (427 aa)
	polr2k	Polymerase (RNA) II (DNA directed) polypeptide K. (58 aa)
	LOC111647896	General transcription factor IIH subunit. (392 aa)
	nelfb	Negative elongation factor complex member B. (583 aa)
	polr2i	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (126 aa)
	gtf2f2	General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (270 aa)
	ercc3	Excision repair cross-complementation group 3. (803 aa)
	supt5h	Transcription elongation factor SPT5. (1084 aa)
	ENSSLDP00000008454	PH_TFIIH domain-containing protein. (61 aa)
	NCBP1	Nuclear cap binding protein subunit 1. (795 aa)
	polr2j	Polymerase (RNA) II (DNA directed) polypeptide J. (117 aa)
	LOC111652387	General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (255 aa)
	gtf2h1	General transcription factor IIH, polypeptide 1. (550 aa)
	polr2l	Polymerase (RNA) II (DNA directed) polypeptide L. (67 aa)
	nelfe	Negative elongation factor complex member E. (344 aa)
	polr2d	Polymerase (RNA) II (DNA directed) polypeptide D. (145 aa)
	polr2f	Polymerase (RNA) II (DNA directed) polypeptide F. (127 aa)
	polr2b	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
	nelfa	Negative elongation factor complex member A. (547 aa)
	POLR2E	RNA polymerase II subunit E. (210 aa)
	nelfcd	Negative elongation factor complex member C/D. (579 aa)
	ctdp1	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1. (1009 aa)
	polr2c	Polymerase (RNA) II (DNA directed) polypeptide C. (275 aa)
	cdk7	Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (343 aa)
	polr2h	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
	polr2g	Polymerase (RNA) II (DNA directed) polypeptide G-like. (172 aa)
	mnat1	MNAT1 component of CDK activating kinase. (236 aa)

Your Current Organism:

Seriola lalandi

NCBI taxonomy Id: 1841481
Other names: S. lalandi dorsalis, Seriola dorsalis, Seriola lalandi dorsalis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSLDP00000008454	ENSSLDP00000020317	ENSSLDP00000008454	ENSSLDP00000020317	PH_TFIIH domain-containing protein.	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.976
ENSSLDP00000008454	LOC111647896	ENSSLDP00000008454	ENSSLDP00000013095	PH_TFIIH domain-containing protein.	General transcription factor IIH subunit.	0.976
ENSSLDP00000008454	LOC111652387	ENSSLDP00000008454	ENSSLDP00000028940	PH_TFIIH domain-containing protein.	General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity.	0.906
ENSSLDP00000008454	NCBP1	ENSSLDP00000008454	ENSSLDP00000028369	PH_TFIIH domain-containing protein.	Nuclear cap binding protein subunit 1.	0.642
ENSSLDP00000008454	POLR2E	ENSSLDP00000008454	ENSSLDP00000006238	PH_TFIIH domain-containing protein.	RNA polymerase II subunit E.	0.940
ENSSLDP00000008454	ccnh	ENSSLDP00000008454	ENSSLDP00000022260	PH_TFIIH domain-containing protein.	Cyclin H; Belongs to the cyclin family.	0.975
ENSSLDP00000008454	cdk7	ENSSLDP00000008454	ENSSLDP00000003400	PH_TFIIH domain-containing protein.	Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily.	0.883
ENSSLDP00000008454	ercc2	ENSSLDP00000008454	ENSSLDP00000026237	PH_TFIIH domain-containing protein.	Excision repair cross-complementation group 2.	0.976
ENSSLDP00000008454	ercc3	ENSSLDP00000008454	ENSSLDP00000011009	PH_TFIIH domain-containing protein.	Excision repair cross-complementation group 3.	0.977
ENSSLDP00000008454	gtf2f1	ENSSLDP00000008454	ENSSLDP00000010971	PH_TFIIH domain-containing protein.	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	0.959
ENSSLDP00000008454	gtf2f2	ENSSLDP00000008454	ENSSLDP00000011183	PH_TFIIH domain-containing protein.	General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity.	0.906
ENSSLDP00000008454	gtf2h3	ENSSLDP00000008454	ENSSLDP00000023295	PH_TFIIH domain-containing protein.	General transcription factor IIH, polypeptide 3.	0.976
ENSSLDP00000008454	gtf2h5	ENSSLDP00000008454	ENSSLDP00000025806	PH_TFIIH domain-containing protein.	General transcription factor IIH, polypeptide 5.	0.973
ENSSLDP00000008454	mnat1	ENSSLDP00000008454	ENSSLDP00000000135	PH_TFIIH domain-containing protein.	MNAT1 component of CDK activating kinase.	0.976
ENSSLDP00000008454	nelfcd	ENSSLDP00000008454	ENSSLDP00000006137	PH_TFIIH domain-containing protein.	Negative elongation factor complex member C/D.	0.507
ENSSLDP00000008454	polr2a	ENSSLDP00000008454	ENSSLDP00000026588	PH_TFIIH domain-containing protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.958
ENSSLDP00000008454	polr2b	ENSSLDP00000008454	ENSSLDP00000021557	PH_TFIIH domain-containing protein.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.939
ENSSLDP00000008454	polr2c	ENSSLDP00000008454	ENSSLDP00000004470	PH_TFIIH domain-containing protein.	Polymerase (RNA) II (DNA directed) polypeptide C.	0.944
ENSSLDP00000008454	polr2d	ENSSLDP00000008454	ENSSLDP00000031887	PH_TFIIH domain-containing protein.	Polymerase (RNA) II (DNA directed) polypeptide D.	0.950
ENSSLDP00000008454	polr2f	ENSSLDP00000008454	ENSSLDP00000032416	PH_TFIIH domain-containing protein.	Polymerase (RNA) II (DNA directed) polypeptide F.	0.942