STRINGSTRING
LOC111653623 LOC111653623 dffa dffa LOC111671959 LOC111671959 bad bad LOC111648908 LOC111648908 LOC111666932 LOC111666932 LOC111655428 LOC111655428 LOC111656030 LOC111656030 LOC111644455 LOC111644455 LOC111653033 LOC111653033 LOC111653021 LOC111653021 htra2 htra2 LOC111669522 LOC111669522 LOC111669521 LOC111669521 LOC111653030 LOC111653030 LOC111669009 LOC111669009 PRF1 PRF1 ENSSLDP00000003095 ENSSLDP00000003095 LOC111644723 LOC111644723 LOC111667746 LOC111667746 ENSSLDP00000003264 ENSSLDP00000003264 LOC111672046 LOC111672046 LOC111661628 LOC111661628 LOC111659106 LOC111659106 LOC111644248 LOC111644248 LOC111672507 LOC111672507 casp8 casp8 LOC111646556 LOC111646556 ctsz ctsz ddit3 ddit3 LOC111673298 LOC111673298 LOC111650100 LOC111650100 casp7 casp7 LOC111650146 LOC111650146 LOC111668900 LOC111668900 LOC111649932 LOC111649932 BCL2 BCL2 parp1 parp1 LOC111649083 LOC111649083 LOC111647234 LOC111647234 jun jun parp2 parp2 LOC111646081 LOC111646081 LOC111648175 LOC111648175 LOC111669110 LOC111669110 LOC111649156 LOC111649156 LOC111662357 LOC111662357 LOC111660531 LOC111660531 bax bax LOC111671507 LOC111671507 LOC111671506 LOC111671506 ikbkb ikbkb LOC111664872 LOC111664872 LOC111665447 LOC111665447 LOC111650698 LOC111650698 LOC111652614 LOC111652614 LOC111657488 LOC111657488 LOC111657489 LOC111657489 itpr3 itpr3 LOC111668412 LOC111668412 LOC111666015 LOC111666015 LOC111649248 LOC111649248 ntrk1 ntrk1 raf1 raf1 lmna lmna LOC111647918 LOC111647918 LOC111655660 LOC111655660 hras hras LOC111648042 LOC111648042 LOC111669226 LOC111669226 eif2ak3 eif2ak3 LOC111669221 LOC111669221 LOC111669222 LOC111669222 LOC111661862 LOC111661862 pdpk1 pdpk1 lmnb2 lmnb2 GADD45B GADD45B LOC111653974 LOC111653974 LOC111659220 LOC111659220 actb actb LOC111669290 LOC111669290 LOC111672962 LOC111672962 LOC111669314 LOC111669314 LOC111647455 LOC111647455 LOC111669302 LOC111669302 pik3r3 pik3r3 LOC111661265 LOC111661265 LOC111658196 LOC111658196 ikbkg ikbkg dab2ip dab2ip LOC111647419 LOC111647419 bcl2l1 bcl2l1 pik3r1 pik3r1 LOC111669331 LOC111669331 ENSSLDP00000020906 ENSSLDP00000020906 LOC111658207 LOC111658207 LOC111666828 LOC111666828 LOC111648134 LOC111648134 LOC111661237 LOC111661237 LOC111645579 LOC111645579 TUBA1A TUBA1A LOC111666176 LOC111666176 parp3 parp3 rela rela LOC111668118 LOC111668118 LOC111644601 LOC111644601 atm atm LOC111660482 LOC111660482 LOC111649592 LOC111649592 ripk1 ripk1 tradd tradd LOC111671654 LOC111671654 ENSSLDP00000024112 ENSSLDP00000024112 dffb dffb map2k2 map2k2 casp9 casp9 LOC111645124 LOC111645124 LOC111657703 LOC111657703 daxx daxx ENSSLDP00000024895 ENSSLDP00000024895 LOC111651024 LOC111651024 LOC111647584 LOC111647584 bcl2 bcl2 AIFM1 AIFM1 LOC111672454 LOC111672454 LOC111655907 LOC111655907 GADD45A GADD45A LOC111670553 LOC111670553 LOC111646321 LOC111646321 LOC111646360 LOC111646360 LOC111646334 LOC111646334 map3k5 map3k5 apaf1 apaf1 LOC111671089 LOC111671089 LOC111653415 LOC111653415 ctsc ctsc LOC111663204 LOC111663204 LOC111644680 LOC111644680 LOC111666336 LOC111666336 LOC111671828 LOC111671828 LOC111664391 LOC111664391 LOC111668761 LOC111668761 ENSSLDP00000028517 ENSSLDP00000028517 kras kras sptan1 sptan1 itpr2 itpr2 LOC111658373 LOC111658373 LOC111645313 LOC111645313 GADD45B-2 GADD45B-2 LOC111666979 LOC111666979 LOC111663282 LOC111663282 parp4 parp4 LOC111646489 LOC111646489 ern1 ern1 LOC111664455 LOC111664455 ctso ctso casp6 casp6 nfkbia nfkbia LOC111669911 LOC111669911 map2k1 map2k1 tnfsf10 tnfsf10 LOC111667597 LOC111667597 LOC111668865 LOC111668865 LOC111663309 LOC111663309 ctsd ctsd xiap xiap eif2s1 eif2s1 pik3cb pik3cb LOC111645667 LOC111645667 ctsl ctsl LOC111670053 LOC111670053 mapk1 mapk1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC111653623Diablo, IAP-binding mitochondrial protein a. (269 aa)
dffaDNA fragmentation factor, alpha polypeptide. (314 aa)
LOC111671959Fas ligand (TNF superfamily, member 6); Belongs to the tumor necrosis factor family. (262 aa)
badBCL2 associated agonist of cell death b. (167 aa)
LOC111648908Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
LOC111666932Cathepsin H; Belongs to the peptidase C1 family. (324 aa)
LOC111655428Protein kinase domain-containing protein. (762 aa)
LOC111656030Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
LOC111644455Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (116 aa)
LOC111653033Si:ch211-153j24.3. (403 aa)
LOC111653021V-fos FBJ murine osteosarcoma viral oncogene homolog Ab. (381 aa)
htra2Si:dkey-33c12.12. (444 aa)
LOC111669522Uncharacterized protein; Belongs to the peptidase C2 family. (700 aa)
LOC111669521Calpain 2, (m/II) large subunit, like; Belongs to the peptidase C2 family. (726 aa)
LOC111653030Cathepsin Bb; Belongs to the peptidase C1 family. (332 aa)
LOC111669009Nerve growth factor a (beta polypeptide); Belongs to the NGF-beta family. (293 aa)
PRF1Perforin 1. (576 aa)
ENSSLDP00000003095Uncharacterized protein. (596 aa)
LOC111644723Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (239 aa)
LOC111667746Inositol 1,4,5-trisphosphate receptor, type 1a. (2709 aa)
ENSSLDP00000003264Uncharacterized protein. (591 aa)
LOC111672046Baculoviral IAP repeat containing 5a. (142 aa)
LOC111661628Si:ch211-1i11.3. (1328 aa)
LOC111659106Cathepsin H; Belongs to the peptidase C1 family. (331 aa)
LOC111644248Uncharacterized protein; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (297 aa)
LOC111672507Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a. (308 aa)
casp8Caspase 8, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (490 aa)
LOC111646556Mitogen-activated protein kinase. (420 aa)
ctszCathepsin Z; Belongs to the peptidase C1 family. (306 aa)
ddit3DNA-damage-inducible transcript 3. (312 aa)
LOC111673298Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
LOC111650100Tubulin_C domain-containing protein; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (217 aa)
casp7Caspase 7, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (309 aa)
LOC111650146Uncharacterized protein; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (172 aa)
LOC111668900Baculoviral IAP repeat containing 5b. (147 aa)
LOC111649932Uncharacterized protein. (423 aa)
BCL2BCL2 apoptosis regulator. (212 aa)
parp1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa)
LOC111649083Zgc:55558. (187 aa)
LOC111647234Zgc:55262; Belongs to the peptidase C2 family. (706 aa)
junBZIP domain-containing protein; Belongs to the bZIP family. (321 aa)
parp2Poly [ADP-ribose] polymerase. (650 aa)
LOC111646081Uncharacterized protein. (1036 aa)
LOC111648175Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (155 aa)
LOC111669110Cathepsin 12; Belongs to the peptidase C1 family. (329 aa)
LOC111649156Uncharacterized protein. (258 aa)
LOC111662357Nerve growth factor b (beta polypeptide); Belongs to the NGF-beta family. (202 aa)
LOC111660531Mitogen-activated protein kinase kinase kinase 14a. (881 aa)
baxBCL2 associated X, apoptosis regulator a. (192 aa)
LOC111671507Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
LOC111671506Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
ikbkbInhibitor of nuclear factor kappa B kinase subunit beta. (773 aa)
LOC111664872TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (520 aa)
LOC111665447Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (482 aa)
LOC111650698Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (377 aa)
LOC111652614Mitogen-activated protein kinase kinase 2b. (395 aa)
LOC111657488Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (255 aa)
LOC111657489Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (247 aa)
itpr3Inositol 1,4,5-trisphosphate receptor, type 3. (2577 aa)
LOC111668412Cathepsin K; Belongs to the peptidase C1 family. (358 aa)
LOC111666015TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (557 aa)
LOC111649248BH4_2 domain-containing protein. (221 aa)
ntrk1Tyrosine-protein kinase receptor. (801 aa)
raf1Raf-1 proto-oncogene, serine/threonine kinase a. (675 aa)
lmnaLamin A; Belongs to the intermediate filament family. (649 aa)
LOC111647918TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (569 aa)
LOC111655660Tumor necrosis factor b (TNF superfamily, member 2). (254 aa)
hrasHRas proto-oncogene, GTPase a. (189 aa)
LOC111648042Uncharacterized protein. (409 aa)
LOC111669226MCL1 apoptosis regulator, BCL2 family member b. (285 aa)
eif2ak3Eukaryotic translation initiation factor 2-alpha kinase 3. (1107 aa)
LOC111669221Cathepsin S, ortholog2, tandem duplicate 1; Belongs to the peptidase C1 family. (337 aa)
LOC111669222Cathepsin K; Belongs to the peptidase C1 family. (330 aa)
LOC111661862Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
pdpk13-phosphoinositide dependent protein kinase 1b. (531 aa)
lmnb2Lamin B2; Belongs to the intermediate filament family. (610 aa)
GADD45BGrowth arrest and DNA damage inducible beta. (160 aa)
LOC111653974Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
LOC111659220Uncharacterized protein; Belongs to the peptidase C1 family. (328 aa)
actbUncharacterized protein. (375 aa)
LOC111669290Uncharacterized protein. (201 aa)
LOC111672962MACPF domain-containing protein. (524 aa)
LOC111669314Zgc:153993. (204 aa)
LOC111647455Uncharacterized protein; Belongs to the peptidase C2 family. (720 aa)
LOC111669302Lamin L3; Belongs to the intermediate filament family. (594 aa)
pik3r3Phosphoinositide-3-kinase, regulatory subunit 3b (gamma). (731 aa)
LOC111661265Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC111658196Mitogen-activated protein kinase. (411 aa)
ikbkgInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (598 aa)
dab2ipDAB2 interacting protein b. (1162 aa)
LOC111647419Septin 4a; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (544 aa)
bcl2l1BCL2 like 1. (232 aa)
pik3r1Phosphoinositide-3-kinase, regulatory subunit 1 (alpha). (728 aa)
LOC111669331Growth arrest and DNA-damage-inducible, gamma b, tandem duplicate 1. (154 aa)
ENSSLDP00000020906Ribosomal_L7Ae domain-containing protein. (238 aa)
LOC111658207Component of inhibitor of nuclear factor kappa B kinase complex. (734 aa)
LOC111666828Tumor necrosis factor receptor superfamily, member a. (450 aa)
LOC111648134JunE proto-oncogene, AP-1 transcription factor subunit. (343 aa)
LOC111661237Growth arrest and DNA-damage-inducible, alpha, a. (163 aa)
LOC111645579Uncharacterized protein; Belongs to the intermediate filament family. (642 aa)
TUBA1ATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
LOC111666176Baculoviral IAP repeat containing 2. (642 aa)
parp3Poly [ADP-ribose] polymerase. (529 aa)
relaV-rel avian reticuloendotheliosis viral oncogene homolog A. (632 aa)
LOC111668118Zgc:136872; Belongs to the peptidase C2 family. (697 aa)
LOC111644601Cytochrome c, somatic b; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
atmNon-specific serine/threonine protein kinase. (3036 aa)
LOC111660482Perforin 1.9. (586 aa)
LOC111649592Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (400 aa)
ripk1Receptor (TNFRSF)-interacting serine-threonine kinase 1, like. (682 aa)
traddTnfrsf1a-associated via death domain. (292 aa)
LOC111671654Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (946 aa)
ENSSLDP00000024112Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
dffbDNA fragmentation factor, beta polypeptide (caspase-activated DNase). (380 aa)
map2k2Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily. (399 aa)
casp9Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (434 aa)
LOC111645124Growth arrest and DNA-damage-inducible, gamma a. (159 aa)
LOC111657703Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (392 aa)
daxxDeath-domain associated protein. (748 aa)
ENSSLDP00000024895Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (480 aa)
LOC111651024Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (719 aa)
LOC111647584Uncharacterized protein. (375 aa)
bcl2BCL2 apoptosis regulator b. (228 aa)
AIFM1Apoptosis inducing factor mitochondria associated 1. (254 aa)
LOC111672454Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
LOC111655907Cathepsin L.1; Belongs to the peptidase C1 family. (334 aa)
GADD45AGrowth arrest and DNA-damage-inducible, alpha, b. (203 aa)
LOC111670553Uncharacterized protein. (467 aa)
LOC111646321Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (397 aa)
LOC111646360Activating transcription factor 4b. (457 aa)
LOC111646334Uncharacterized protein. (682 aa)
map3k5Mitogen-activated protein kinase kinase kinase 5. (1312 aa)
apaf1Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1258 aa)
LOC111671089Phosphoinositide-3-kinase, regulatory subunit 2 (beta). (738 aa)
LOC111653415Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (347 aa)
ctscCathepsin C; Belongs to the peptidase C1 family. (455 aa)
LOC111663204V-fos FBJ murine osteosarcoma viral oncogene homolog Aa. (378 aa)
LOC111644680Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (303 aa)
LOC111666336CD40 ligand; Belongs to the tumor necrosis factor family. (223 aa)
LOC111671828Activating transcription factor 4a. (464 aa)
LOC111664391ADP-ribosylation factor 2b. (1021 aa)
LOC111668761Granzyme 3, tandem duplicate 4; Belongs to the peptidase S1 family. (257 aa)
ENSSLDP00000028517Uncharacterized protein. (164 aa)
krasV-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
sptan1Spectrin alpha, non-erythrocytic 1. (2436 aa)
itpr2Inositol 1,4,5-trisphosphate receptor, type 2. (2629 aa)
LOC111658373Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (300 aa)
LOC111645313Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (482 aa)
GADD45B-2Growth arrest and DNA damage inducible beta. (148 aa)
LOC111666979P53-induced death domain protein 1. (987 aa)
LOC111663282Endoplasmic reticulum to nucleus signaling 2. (979 aa)
parp4Poly [ADP-ribose] polymerase. (1716 aa)
LOC111646489Cathepsin F; Belongs to the peptidase C1 family. (537 aa)
ern1Endoplasmic reticulum to nucleus signaling 1. (1096 aa)
LOC111664455Uncharacterized protein; Belongs to the peptidase C14A family. (267 aa)
ctsoCathepsin O; Belongs to the peptidase C1 family. (344 aa)
casp6Caspase 6, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family. (301 aa)
nfkbiaNuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b. (318 aa)
LOC111669911Tumor necrosis factor receptor superfamily, member 1a. (392 aa)
map2k1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (371 aa)
tnfsf10TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (292 aa)
LOC111667597Uncharacterized protein; Belongs to the peptidase C14A family. (294 aa)
LOC111668865Cathepsin Ba; Belongs to the peptidase C1 family. (330 aa)
LOC111663309Caspase 3, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family. (277 aa)
ctsdCathepsin D; Belongs to the peptidase A1 family. (397 aa)
xiapX-linked inhibitor of apoptosis. (468 aa)
eif2s1Eukaryotic translation initiation factor 2, subunit 1 alpha b. (315 aa)
pik3cbPhosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1076 aa)
LOC111645667Perforin 1.5. (523 aa)
ctslSi:dkey-26g8.5; Belongs to the peptidase C1 family. (336 aa)
LOC111670053Uncharacterized protein. (321 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (369 aa)
Your Current Organism:
Seriola lalandi
NCBI taxonomy Id: 1841481
Other names: S. lalandi dorsalis, Seriola dorsalis, Seriola lalandi dorsalis
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