STRINGSTRING
APG26660.1 APG26660.1 APG26449.1 APG26449.1 APG26453.1 APG26453.1 APG26476.1 APG26476.1 APG28946.1 APG28946.1 hisG hisG mtnP mtnP APG26495.1 APG26495.1 APG26521.1 APG26521.1 APG26572.1 APG26572.1 lpxB lpxB APG26630.1 APG26630.1 APG28965.1 APG28965.1 APG26632.1 APG26632.1 APG26635.1 APG26635.1 APG26638.1 APG26638.1 APG26647.1 APG26647.1 APG26665.1 APG26665.1 APG26666.1 APG26666.1 APG28972.1 APG28972.1 apt apt purF purF pyrE pyrE APG26839.1 APG26839.1 pyrR pyrR APG26940.1 APG26940.1 APG26942.1 APG26942.1 APG26983.1 APG26983.1 APG27001.1 APG27001.1 lgt lgt tgt tgt queA queA APG27274.1 APG27274.1 tgt-2 tgt-2 rlpA rlpA APG27375.1 APG27375.1 mrdB mrdB cobT cobT trpD trpD mltG mltG APG27787.1 APG27787.1 hisF hisF hisH hisH hisG-2 hisG-2 ppnP ppnP APG27995.1 APG27995.1 APG27996.1 APG27996.1 APG27997.1 APG27997.1 APG28194.1 APG28194.1 APG28281.1 APG28281.1 APG28316.1 APG28316.1 APG28389.1 APG28389.1 APG28437.1 APG28437.1 APG28567.1 APG28567.1 glgA glgA APG29132.1 APG29132.1 APG28676.1 APG28676.1 APG28678.1 APG28678.1 APG28699.1 APG28699.1 APG28714.1 APG28714.1 APG28765.1 APG28765.1 APG28876.1 APG28876.1 murG murG
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
APG26660.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (302 aa)
APG26449.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (385 aa)
APG26453.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (434 aa)
APG26476.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (555 aa)
APG28946.1Glycosyl transferase family 1; Derived by automated computational analysis using gene prediction method: Protein Homology. (372 aa)
hisGATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (291 aa)
mtnPMethylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. (287 aa)
APG26495.1Hypothetical protein; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (271 aa)
APG26521.1N-acyl homoserine lactonase; Derived by automated computational analysis using gene prediction method: Protein Homology. (264 aa)
APG26572.1Nicotinate-nucleotide diphosphorylase (carboxylating); Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family. (274 aa)
lpxBlipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (382 aa)
APG26630.1Hypothetical protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (431 aa)
APG28965.1Lipopolysaccharide heptosyltransferase II; Derived by automated computational analysis using gene prediction method: Protein Homology. (330 aa)
APG26632.1Lipopolysaccharide heptosyltransferase I; Derived by automated computational analysis using gene prediction method: Protein Homology. (348 aa)
APG26635.1Lipopolysaccharide core heptose(I) kinase RfaP; Catalyzes the phosphorylation of heptose(I) of the outer membrane lipopolysaccharide core; Belongs to the protein kinase superfamily. KdkA/rfaP family. (274 aa)
APG26638.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (527 aa)
APG26647.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (263 aa)
APG26665.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (425 aa)
APG26666.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (375 aa)
APG28972.1Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (169 aa)
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (171 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (468 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (187 aa)
APG26839.1Lytic transglycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (190 aa)
pyrRBifunctional pyr operon transcriptional regulator/uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. (178 aa)
APG26940.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (357 aa)
APG26942.1Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (372 aa)
APG26983.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (382 aa)
APG27001.1Alpha-glucan phosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (570 aa)
lgtProlipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. (260 aa)
tgttRNA guanosine(34) transglycosylase Tgt; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose t [...] (375 aa)
queAtRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (343 aa)
APG27274.1Penicillin-binding protein 1C; Derived by automated computational analysis using gene prediction method: Protein Homology. (780 aa)
tgt-2tRNA guanosine(34) transglycosylase Tgt; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose t [...] (369 aa)
rlpAHypothetical protein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (251 aa)
APG27375.1Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (478 aa)
mrdBRod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. (365 aa)
cobTNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (356 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (349 aa)
mltGHypothetical protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. (332 aa)
APG27787.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (248 aa)
hisFImidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (255 aa)
hisHImidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (206 aa)
hisG-2ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. (220 aa)
ppnPHypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. (104 aa)
APG27995.1Trehalose-6-phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (475 aa)
APG27996.1Glycosyl transferase family 1; Derived by automated computational analysis using gene prediction method: Protein Homology. (420 aa)
APG27997.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (228 aa)
APG28194.1Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (800 aa)
APG28281.1Glycosyl transferase family 1; Derived by automated computational analysis using gene prediction method: Protein Homology. (423 aa)
APG28316.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (354 aa)
APG28389.1Glycoside hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (98 aa)
APG28437.14-alpha-glucanotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (500 aa)
APG28567.1Laccase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the multicopper oxidase YfiH/RL5 family. (263 aa)
glgAStarch synthase; Synthesizes alpha-1,4-glucan chains using ADP-glucose. (483 aa)
APG29132.1Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). (774 aa)
APG28676.1Prolipoprotein diacylglyceryl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (350 aa)
APG28678.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (387 aa)
APG28699.1Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (178 aa)
APG28714.1Uridine phosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (260 aa)
APG28765.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (740 aa)
APG28876.1Cell division protein FtsW; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SEDS family. (368 aa)
murGUndecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (360 aa)
Your Current Organism:
Pelobacter sp. SFB93
NCBI taxonomy Id: 1842532
Other names: P. sp. SFB93
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