STRINGSTRING
OIJ24370.1 OIJ24370.1 OIJ28800.1 OIJ28800.1 OIJ28906.1 OIJ28906.1 OIJ28909.1 OIJ28909.1 OIJ28633.1 OIJ28633.1 OIJ28295.1 OIJ28295.1 gcvH gcvH gcvP gcvP OIJ28217.1 OIJ28217.1 OIJ27927.1 OIJ27927.1 OIJ27949.1 OIJ27949.1 OIJ27880.1 OIJ27880.1 ectC ectC OIJ27882.1 OIJ27882.1 OIJ27289.1 OIJ27289.1 OIJ27318.1 OIJ27318.1 OIJ27332.1 OIJ27332.1 OIJ27334.1 OIJ27334.1 OIJ27409.1 OIJ27409.1 OIJ27388.1 OIJ27388.1 ilvA ilvA OIJ27234.1 OIJ27234.1 OIJ27161.1 OIJ27161.1 OIJ27216.1 OIJ27216.1 OIJ26867.1 OIJ26867.1 OIJ26908.1 OIJ26908.1 OIJ26786.1 OIJ26786.1 OIJ26569.1 OIJ26569.1 gcvT gcvT gcvT-2 gcvT-2 gcvH-2 gcvH-2 OIJ26089.1 OIJ26089.1 OIJ26097.1 OIJ26097.1 trpA trpA trpB trpB OIJ25816.1 OIJ25816.1 OIJ25767.1 OIJ25767.1 OIJ25705.1 OIJ25705.1 OIJ25719.1 OIJ25719.1 OIJ25603.1 OIJ25603.1 glyA glyA OIJ25607.1 OIJ25607.1 OIJ25608.1 OIJ25608.1 OIJ25609.1 OIJ25609.1 OIJ25610.1 OIJ25610.1 OIJ25620.1 OIJ25620.1 OIJ25628.1 OIJ25628.1 OIJ25520.1 OIJ25520.1 OIJ25406.1 OIJ25406.1 OIJ25479.1 OIJ25479.1 asd asd OIJ25357.1 OIJ25357.1 OIJ25281.1 OIJ25281.1 OIJ25077.1 OIJ25077.1 OIJ25111.1 OIJ25111.1 serC serC gpmA gpmA OIJ24947.1 OIJ24947.1 OIJ24814.1 OIJ24814.1 OIJ24716.1 OIJ24716.1 OIJ24531.1 OIJ24531.1 OIJ24532.1 OIJ24532.1 thrB thrB OIJ24557.1 OIJ24557.1 OIJ24212.1 OIJ24212.1 OIJ24033.1 OIJ24033.1 OIJ23960.1 OIJ23960.1 OIJ23908.1 OIJ23908.1 glyA-2 glyA-2 OIJ23805.1 OIJ23805.1 OIJ23670.1 OIJ23670.1 OIJ23623.1 OIJ23623.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
OIJ24370.1Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (471 aa)
OIJ28800.1Arsenate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ArsC family. (116 aa)
OIJ28906.1Choline dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (535 aa)
OIJ28909.1Choline dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (548 aa)
OIJ28633.1Creatinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (374 aa)
OIJ28295.1Gamma-aminobutyraldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (480 aa)
gcvHGlycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (130 aa)
gcvPGlycine dehydrogenase (aminomethyl-transferring); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (962 aa)
OIJ28217.1Glucose-methanol-choline oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (532 aa)
OIJ27927.1Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (466 aa)
OIJ27949.1Threonine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (403 aa)
OIJ27880.1Ectoine hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (299 aa)
ectCL-ectoine synthase; Catalyzes the circularization of gamma-N-acetyl-alpha,gamma- diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4- pyrimidine carboxylic acid), which is an excellent osmoprotectant. (138 aa)
OIJ27882.1Diaminobutyrate--2-oxoglutarate transaminase; Catalyzes reversively the conversion of L-aspartate beta- semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (580 aa)
OIJ27289.1Alanine racemase; Derived by automated computational analysis using gene prediction method: Protein Homology. (402 aa)
OIJ27318.1Inhibition of morphological differentiation protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (264 aa)
OIJ27332.1Alanine racemase; Derived by automated computational analysis using gene prediction method: Protein Homology. (407 aa)
OIJ27334.1Alanine racemase; Derived by automated computational analysis using gene prediction method: Protein Homology. (402 aa)
OIJ27409.1Urea carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (254 aa)
OIJ27388.1Urea carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (284 aa)
ilvAThreonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (418 aa)
OIJ27234.1Histidine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (239 aa)
OIJ27161.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (342 aa)
OIJ27216.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (358 aa)
OIJ26867.1Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (466 aa)
OIJ26908.1Xaa-Pro aminopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase M24B family. (474 aa)
OIJ26786.1Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. (576 aa)
OIJ26569.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (324 aa)
gcvTGlycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. (380 aa)
gcvT-2Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. (367 aa)
gcvH-2Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (123 aa)
OIJ26089.1L-serine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. (468 aa)
OIJ26097.1Hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (317 aa)
trpATryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (265 aa)
trpBTryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (414 aa)
OIJ25816.1Pyridine nucleotide-disulfide oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (484 aa)
OIJ25767.1Amino acid oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (359 aa)
OIJ25705.1Phosphoserine phosphatase SerB; Derived by automated computational analysis using gene prediction method: Protein Homology. (414 aa)
OIJ25719.1Phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (303 aa)
OIJ25603.1Sarcosine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. (829 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (431 aa)
OIJ25607.1Sarcosine oxidase subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. (96 aa)
OIJ25608.1Ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (967 aa)
OIJ25609.1Sarcosine oxidase subunit gamma; Derived by automated computational analysis using gene prediction method: Protein Homology. (210 aa)
OIJ25610.1L-serine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. (457 aa)
OIJ25620.1Hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (334 aa)
OIJ25628.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (329 aa)
OIJ25520.1Glycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycerate kinase type-1 family. (376 aa)
OIJ25406.1Dihydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (310 aa)
OIJ25479.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (314 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (347 aa)
OIJ25357.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (587 aa)
OIJ25281.1Dihydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (318 aa)
OIJ25077.1Tyramine oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (672 aa)
OIJ25111.1Amino acid deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (444 aa)
serCPhosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (371 aa)
gpmAPhosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (246 aa)
OIJ24947.1Threonine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (423 aa)
OIJ24814.1D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (398 aa)
OIJ24716.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycerate kinase type-1 family. (361 aa)
OIJ24531.1Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (437 aa)
OIJ24532.1Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (355 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (301 aa)
OIJ24557.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (297 aa)
OIJ24212.1Hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (309 aa)
OIJ24033.1Glycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycerate kinase type-1 family. (377 aa)
OIJ23960.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (212 aa)
OIJ23908.1Putrescine oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (452 aa)
glyA-2Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (493 aa)
OIJ23805.1Hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (318 aa)
OIJ23670.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (340 aa)
OIJ23623.1Amino acid oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (525 aa)
Your Current Organism:
Nocardioides luteus
NCBI taxonomy Id: 1844
Other names: ATCC 43052, CCUG 37986, CIP 103450, DSM 43366, IFO 14491, IMET 7830, JCM 3358, KCTC 9575, LMG 16209, LMG:16209, N. luteus, NBRC 14491
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