STRINGSTRING
AOT01958.1 AOT01958.1 dapD dapD AOT01963.1 AOT01963.1 AOT01993.1 AOT01993.1 AOT05248.1 AOT05248.1 AOT02031.1 AOT02031.1 fhs fhs AOT02120.1 AOT02120.1 thyA thyA AOT02137.1 AOT02137.1 AOT02144.1 AOT02144.1 AOT02163.1 AOT02163.1 AOT02164.1 AOT02164.1 AOT02216.1 AOT02216.1 AOT02226.1 AOT02226.1 AOT05266.1 AOT05266.1 AOT02235.1 AOT02235.1 AOT05267.1 AOT05267.1 AOT02236.1 AOT02236.1 AOT02256.1 AOT02256.1 hisD hisD AOT02384.1 AOT02384.1 AOT02386.1 AOT02386.1 AOT02389.1 AOT02389.1 proC proC aroQ aroQ AOT02520.1 AOT02520.1 AOT02538.1 AOT02538.1 AOT02553.1 AOT02553.1 AOT02561.1 AOT02561.1 AOT05324.1 AOT05324.1 AOT02584.1 AOT02584.1 AOT02596.1 AOT02596.1 AOT02605.1 AOT02605.1 trpF trpF AOT02700.1 AOT02700.1 AOT02701.1 AOT02701.1 metZ metZ AOT02705.1 AOT02705.1 AOT05343.1 AOT05343.1 glsA glsA AOT05348.1 AOT05348.1 pat pat AOT02933.1 AOT02933.1 purU purU AOT03022.1 AOT03022.1 pheA pheA AOT03118.1 AOT03118.1 AOT03142.1 AOT03142.1 AOT03143.1 AOT03143.1 AOT03146.1 AOT03146.1 AOT03178.1 AOT03178.1 AOT03323.1 AOT03323.1 AOT03336.1 AOT03336.1 AOT03340.1 AOT03340.1 AOT03341.1 AOT03341.1 AOT03362.1 AOT03362.1 AOT05460.1 AOT05460.1 gcvP gcvP gcvT gcvT gcvH gcvH glyA glyA AOT03506.1 AOT03506.1 AOT03520.1 AOT03520.1 AOT05483.1 AOT05483.1 pat-2 pat-2 maiA maiA AOT03691.1 AOT03691.1 folD folD AOT03694.1 AOT03694.1 AOT03695.1 AOT03695.1 purU-2 purU-2 glyA-2 glyA-2 AOT03698.1 AOT03698.1 AOT03699.1 AOT03699.1 purN purN purH purH purU-3 purU-3 glyA-3 glyA-3 folD-2 folD-2 AOT03797.1 AOT03797.1 ahcY ahcY AOT03906.1 AOT03906.1 kbl kbl AOT03908.1 AOT03908.1 AOT03913.1 AOT03913.1 metXA metXA AOT03985.1 AOT03985.1 dapB dapB dapA dapA dapF dapF hisC hisC hisB hisB hisH hisH hisA hisA argC argC argJ argJ argB argB argD argD AOT04064.1 AOT04064.1 argR argR argG argG argH argH AOT04096.1 AOT04096.1 gcvH-2 gcvH-2 AOT04113.1 AOT04113.1 hisD-2 hisD-2 AOT04148.1 AOT04148.1 AOT04152.1 AOT04152.1 pepA pepA AOT04206.1 AOT04206.1 hisE hisE hisG hisG hisF hisF hisI hisI trpE trpE trpC trpC trpB trpB trpA trpA AOT04236.1 AOT04236.1 gltD gltD AOT04276.1 AOT04276.1 AOT04453.1 AOT04453.1 AOT04455.1 AOT04455.1 AOT04480.1 AOT04480.1 AOT04538.1 AOT04538.1 AOT04544.1 AOT04544.1 trpD trpD metK metK aroB aroB aroK aroK aroC aroC AOT04758.1 AOT04758.1 AOT04775.1 AOT04775.1 AOT04828.1 AOT04828.1 AOT04829.1 AOT04829.1 metE metE AOT04858.1 AOT04858.1 proA proA proB proB AOT04892.1 AOT04892.1 AOT04916.1 AOT04916.1 AOT04917.1 AOT04917.1 AOT04996.1 AOT04996.1 AOT05024.1 AOT05024.1 ASPU41_18670 ASPU41_18670 thrB thrB AOT05103.1 AOT05103.1 AOT05104.1 AOT05104.1 lysA lysA AOT05117.1 AOT05117.1 AOT05118.1 AOT05118.1 aroA aroA AOT05137.1 AOT05137.1 AOT05170.1 AOT05170.1 AOT05181.1 AOT05181.1 AOT05182.1 AOT05182.1 AOT05233.1 AOT05233.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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AOT01958.1Succinyl-diaminopimelate desuccinylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (384 aa)
dapD2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. (336 aa)
AOT01963.1Succinyldiaminopimelate transaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (382 aa)
AOT01993.1Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (387 aa)
AOT05248.1Shikimate 5-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (265 aa)
AOT02031.1Carboxylate--amine ligase; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. (383 aa)
fhsFormate--tetrahydrofolate ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the formate--tetrahydrofolate ligase family. (549 aa)
AOT02120.1Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (405 aa)
thyAThymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (267 aa)
AOT02137.1Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (195 aa)
AOT02144.1Aspartate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate-semialdehyde dehydrogenase family. (376 aa)
AOT02163.1Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (400 aa)
AOT02164.1Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (461 aa)
AOT02216.1Pyridine nucleotide-disulfide oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (481 aa)
AOT02226.1Pyridine nucleotide-disulfide oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (490 aa)
AOT05266.1Sulfate adenylyltransferase; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (474 aa)
AOT02235.1Sulfate adenylyltransferase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (313 aa)
AOT05267.1Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. (237 aa)
AOT02236.1Sulfite reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (582 aa)
AOT02256.1Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (403 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (439 aa)
AOT02384.1Haloacid dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (272 aa)
AOT02386.13-deoxy-7-phosphoheptulonate synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (370 aa)
AOT02389.1Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (445 aa)
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (277 aa)
aroQType II 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (157 aa)
AOT02520.1Pyridine nucleotide-disulfide oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (398 aa)
AOT02538.1Dihydrodipicolinate synthase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DapA family. (301 aa)
AOT02553.1Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1216 aa)
AOT02561.1L-asparaginase; Derived by automated computational analysis using gene prediction method: Protein Homology. (339 aa)
AOT05324.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (283 aa)
AOT02584.1Dihydrodipicolinate synthase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DapA family. (302 aa)
AOT02596.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (122 aa)
AOT02605.1Hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (306 aa)
trpFPhosphoribosylanthranilate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpF family. (203 aa)
AOT02700.1Anthranilate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (681 aa)
AOT02701.14-amino-4-deoxychorismate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (319 aa)
metZO-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. (402 aa)
AOT02705.1Carboxylate--amine ligase; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. (394 aa)
AOT05343.11-pyrroline-5-carboxylate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (1171 aa)
glsADerived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutaminase family. (605 aa)
AOT05348.1Sulfite oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (372 aa)
patAminotransferase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. (390 aa)
AOT02933.1Anthranilate synthase component II; Derived by automated computational analysis using gene prediction method: Protein Homology. (213 aa)
purUFormyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (301 aa)
AOT03022.1Methylenetetrahydrofolate reductase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the methylenetetrahydrofolate reductase family. (275 aa)
pheAPrephenate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (326 aa)
AOT03118.1N-acetylglutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the acetyltransferase family. (169 aa)
AOT03142.1Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (187 aa)
AOT03143.1Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology. (145 aa)
AOT03146.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (340 aa)
AOT03178.1Hypothetical protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. (249 aa)
AOT03323.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (195 aa)
AOT03336.1Methionine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (402 aa)
AOT03340.1CoA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (165 aa)
AOT03341.1O-acetylhomoserine aminocarboxypropyltransferase; Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; Derived by automated computational analysis using gene prediction method: Protein Homology. (455 aa)
AOT03362.1Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (452 aa)
AOT05460.1Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (396 aa)
gcvPGlycine dehydrogenase (aminomethyl-transferring); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (962 aa)
gcvTGlycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. (387 aa)
gcvHGlycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (127 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (440 aa)
AOT03506.1L-serine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. (473 aa)
AOT03520.1Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (375 aa)
AOT05483.1Transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (605 aa)
pat-2Histidinol-phosphate transaminase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. (365 aa)
maiAAsp/Glu racemase; Catalyzes cis-trans isomerization of the C2-C3 double bond in maleate to yield fumarate. (272 aa)
AOT03691.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the methylenetetrahydrofolate reductase family. (290 aa)
folDMethenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (291 aa)
AOT03694.1Formimidoyltetrahydrofolate cyclodeaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (208 aa)
AOT03695.1Sarcosine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. (830 aa)
purU-2Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (304 aa)
glyA-2Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (432 aa)
AOT03698.1Sarcosine oxidase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (406 aa)
AOT03699.1Sarcosine oxidase subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. (135 aa)
purNPhosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (194 aa)
purHBifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (564 aa)
purU-3Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (286 aa)
glyA-3Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (433 aa)
folD-2Bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (310 aa)
AOT03797.1Threonine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (412 aa)
ahcYAdenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (495 aa)
AOT03906.1L-threonine 3-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (348 aa)
kblGlycine C-acetyltransferase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. (402 aa)
AOT03908.1FAD-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (372 aa)
AOT03913.1Bifunctional o-acetylhomoserine/o-acetylserine sulfhydrylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (438 aa)
metXAHomoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (361 aa)
AOT03985.1Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (391 aa)
dapB4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (252 aa)
dapA4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (302 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (318 aa)
hisCHistidinol-phosphate transaminase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (372 aa)
hisBImidazoleglycerol-phosphate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (208 aa)
hisHImidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (251 aa)
hisA1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (248 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (343 aa)
argJBifunctional ornithine acetyltransferase/N-acetylglutamate synthase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (388 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (318 aa)
argDAcetylornithine transaminase; Catalyzes the formation of N-acetyl-l-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (430 aa)
AOT04064.1Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (331 aa)
argRArginine repressor; Regulates arginine biosynthesis genes. (177 aa)
argGArgininosuccinate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (401 aa)
argHArgininosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (476 aa)
AOT04096.1Prephenate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (369 aa)
gcvH-2Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (128 aa)
AOT04113.13-deoxy-7-phosphoheptulonate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II DAHP synthase family. (462 aa)
hisD-2Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (467 aa)
AOT04148.1Type I glutamate--ammonia ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (446 aa)
AOT04152.1Type I glutamate--ammonia ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (474 aa)
pepALeucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (508 aa)
AOT04206.1Threonine aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (362 aa)
hisEphosphoribosyl-ATP diphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (87 aa)
hisGATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (280 aa)
hisFImidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (258 aa)
hisIphosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (145 aa)
trpEAnthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (521 aa)
trpCIndole-3-glycerol phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpC family. (258 aa)
trpBTryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (438 aa)
trpATryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (275 aa)
AOT04236.1Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (1536 aa)
gltDGlutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; Derived by automated computational analysis using gene prediction method: Protein Homology. (485 aa)
AOT04276.1Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (219 aa)
AOT04453.1Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (207 aa)
AOT04455.15-amino-6-(5-phosphoribosylamino)uracil reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (196 aa)
AOT04480.1Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (183 aa)
AOT04538.1Phosphoserine phosphatase SerB; Derived by automated computational analysis using gene prediction method: Protein Homology. (301 aa)
AOT04544.1Derived by automated computational analysis using gene prediction method: Protein Homology. (875 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (352 aa)
metKMethionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (411 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (363 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (197 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (399 aa)
AOT04758.1Shikimate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the shikimate dehydrogenase family. (307 aa)
AOT04775.1GCN5 family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (262 aa)
AOT04828.1Gamma-glutamyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (614 aa)
AOT04829.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (331 aa)
metE5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (780 aa)
AOT04858.15,10-methylenetetrahydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methylenetetrahydrofolate reductase family. (327 aa)
proAGlutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (451 aa)
proBGlutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (389 aa)
AOT04892.1Derived by automated computational analysis using gene prediction method: Protein Homology. (851 aa)
AOT04916.1Cysteine synthase A; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. (311 aa)
AOT04917.1Serine O-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (194 aa)
AOT04996.1Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (402 aa)
AOT05024.1Phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (531 aa)
ASPU41_18670Aspartate kinase; Catalyzes reversively the conversion of L-aspartate beta- semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (423 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (322 aa)
AOT05103.1Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (368 aa)
AOT05104.1Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (460 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (499 aa)
AOT05117.1Thiosulfate sulfurtransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (290 aa)
AOT05118.1Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (389 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (471 aa)
AOT05137.1Histidinol-phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (270 aa)
AOT05170.1Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1626 aa)
AOT05181.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (347 aa)
AOT05182.1Chorismate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (155 aa)
AOT05233.1Xaa-Pro aminopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase M24B family. (527 aa)
Your Current Organism:
Arthrobacter sp. U41
NCBI taxonomy Id: 1849032
Other names: A. sp. U41
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