(12 nodes) Cysteine and methionine metabolism network (Arthrobacter sp. U41)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AOT02163.1	Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (400 aa)
	AOT02164.1	Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (461 aa)
	metZ	O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. (402 aa)
	AOT03336.1	Methionine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (402 aa)
	AOT05460.1	Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (396 aa)
	ahcY	Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (495 aa)
	AOT03913.1	Bifunctional o-acetylhomoserine/o-acetylserine sulfhydrylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (438 aa)
	metXA	Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (361 aa)
	AOT04829.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (331 aa)
	thrB	Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (322 aa)
	AOT05104.1	Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (460 aa)
	AOT05118.1	Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (389 aa)

Your Current Organism:

Arthrobacter sp. U41

NCBI taxonomy Id: 1849032
Other names: A. sp. U41

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AOT02163.1	AOT02164.1	ASPU41_01200	ASPU41_01205	Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.997
AOT02163.1	AOT03336.1	ASPU41_01200	ASPU41_08275	Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Methionine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.969
AOT02163.1	AOT03913.1	ASPU41_01200	ASPU41_11875	Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Bifunctional o-acetylhomoserine/o-acetylserine sulfhydrylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.942
AOT02163.1	AOT04829.1	ASPU41_01200	ASPU41_17370	Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.849
AOT02163.1	AOT05104.1	ASPU41_01200	ASPU41_19065	Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.898
AOT02163.1	AOT05118.1	ASPU41_01200	ASPU41_19145	Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.970
AOT02163.1	AOT05460.1	ASPU41_01200	ASPU41_09125	Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.925
AOT02163.1	ahcY	ASPU41_01200	ASPU41_11305	Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.	0.946
AOT02163.1	metXA	ASPU41_01200	ASPU41_11880	Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.	0.960
AOT02163.1	metZ	ASPU41_01200	ASPU41_04390	Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.	0.930
AOT02163.1	thrB	ASPU41_01200	ASPU41_19055	Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.	0.909
AOT02164.1	AOT02163.1	ASPU41_01205	ASPU41_01200	Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.997
AOT02164.1	AOT03336.1	ASPU41_01205	ASPU41_08275	Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Methionine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.928
AOT02164.1	AOT03913.1	ASPU41_01205	ASPU41_11875	Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Bifunctional o-acetylhomoserine/o-acetylserine sulfhydrylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.965
AOT02164.1	AOT04829.1	ASPU41_01205	ASPU41_17370	Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.851
AOT02164.1	AOT05104.1	ASPU41_01205	ASPU41_19065	Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.856
AOT02164.1	AOT05118.1	ASPU41_01205	ASPU41_19145	Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.877
AOT02164.1	AOT05460.1	ASPU41_01205	ASPU41_09125	Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.992
AOT02164.1	ahcY	ASPU41_01205	ASPU41_11305	Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.	0.992
AOT02164.1	metXA	ASPU41_01205	ASPU41_11880	Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.	0.933