(33 nodes) Regulation of catalytic activity, and Cargo trafficking to the periciliary membrane network (Giardia lamblia ATCC 50803)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GL50803_95593	Kinase, NEK. (376 aa)
	GL50803_17318	Kinase, NEK. (1230 aa)
	GL50803_17216	Kinase, NEK. (844 aa)
	GL50803_16535	Tubulin specific chaperone E. (618 aa)
	GL50803_14648	Kinase, NEK-frag. (454 aa)
	GL50803_10893	Kinase, NEK. (321 aa)
	GL50803_115572	Kinase, Wee. (2528 aa)
	GL50803_137676	Kinase, NEK. (340 aa)
	GL50803_13478	ARL1; Belongs to the small GTPase superfamily. Arf family. (179 aa)
	GL50803_87358	Chorein. (3274 aa)
	GL50803_10145	Tubulin specific chaperone D. (1291 aa)
	GL50803_15906	Tubulin specific chaperone D. (297 aa)
	GL50803_16826	Kinase, NEK-frag. (497 aa)
	GL50803_114307	Kinase, NEK. (913 aa)
	GL50803_11390	Kinase, NEK. (777 aa)
	GL50803_15411	Kinase, NEK-frag. (706 aa)
	GL50803_5375	Kinase, NEK; Belongs to the protein kinase superfamily. (405 aa)
	GL50803_5374	Tubulin specific chaperone B. (239 aa)
	GL50803_7514	Kinase, NEK. (679 aa)
	GL50803_14835	Kinase, NEK. (1049 aa)
	GL50803_11311	Kinase, NEK; Belongs to the protein kinase superfamily. (367 aa)
	GL50803_16215	Protein kinase domain-containing protein. (875 aa)
	GL50803_14252	Uncharacterized protein. (390 aa)
	GL50803_4192	ARL2. (197 aa)
	GL50803_27147	GMP_PDE_delta domain-containing protein. (168 aa)
	GL50803_16263	Sjogren's syndrome nuclear autoantigen 1-like protein. (106 aa)
	GL50803_7579	Kinase, NEK-frag. (300 aa)
	GL50803_6691	GA binding protein beta-1 chain. (215 aa)
	GL50803_13708	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (2527 aa)
	GL50803_101866	Kinase, NEK. (809 aa)
	GL50803_7655	C-CAP/cofactor C-like domain-containing protein. (437 aa)
	GL50803_5554	Kinase, NEK-frag. (595 aa)
	GL50803_137706	Kinase, NEK. (595 aa)

Your Current Organism:

Giardia lamblia ATCC 50803

NCBI taxonomy Id: 184922
Other names: G. lamblia ATCC 50803, Giardia intestinalis ATCC 50803

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GL50803_10145	GL50803_15906	A8BDA2	A8BEZ7	Tubulin specific chaperone D.	Tubulin specific chaperone D.	0.542
GL50803_10145	GL50803_16535	A8BDA2	A8B5R2	Tubulin specific chaperone D.	Tubulin specific chaperone E.	0.618
GL50803_10145	GL50803_4192	A8BDA2	A8BQH7	Tubulin specific chaperone D.	ARL2.	0.987
GL50803_10145	GL50803_5374	A8BDA2	A8BJT5	Tubulin specific chaperone D.	Tubulin specific chaperone B.	0.804
GL50803_10145	GL50803_7655	A8BDA2	A8BWX1	Tubulin specific chaperone D.	C-CAP/cofactor C-like domain-containing protein.	0.542
GL50803_13478	GL50803_15906	A8BBS6	A8BEZ7	ARL1; Belongs to the small GTPase superfamily. Arf family.	Tubulin specific chaperone D.	0.875
GL50803_13478	GL50803_27147	A8BBS6	A8BRM2	ARL1; Belongs to the small GTPase superfamily. Arf family.	GMP_PDE_delta domain-containing protein.	0.999
GL50803_13478	GL50803_4192	A8BBS6	A8BQH7	ARL1; Belongs to the small GTPase superfamily. Arf family.	ARL2.	0.428
GL50803_13478	GL50803_7655	A8BBS6	A8BWX1	ARL1; Belongs to the small GTPase superfamily. Arf family.	C-CAP/cofactor C-like domain-containing protein.	0.875
GL50803_13708	GL50803_6691	A8BU27	A8BSQ0	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.	GA binding protein beta-1 chain.	0.682
GL50803_15906	GL50803_10145	A8BEZ7	A8BDA2	Tubulin specific chaperone D.	Tubulin specific chaperone D.	0.542
GL50803_15906	GL50803_13478	A8BEZ7	A8BBS6	Tubulin specific chaperone D.	ARL1; Belongs to the small GTPase superfamily. Arf family.	0.875
GL50803_15906	GL50803_27147	A8BEZ7	A8BRM2	Tubulin specific chaperone D.	GMP_PDE_delta domain-containing protein.	0.641
GL50803_15906	GL50803_4192	A8BEZ7	A8BQH7	Tubulin specific chaperone D.	ARL2.	0.409
GL50803_16535	GL50803_10145	A8B5R2	A8BDA2	Tubulin specific chaperone E.	Tubulin specific chaperone D.	0.618
GL50803_16535	GL50803_5374	A8B5R2	A8BJT5	Tubulin specific chaperone E.	Tubulin specific chaperone B.	0.950
GL50803_27147	GL50803_13478	A8BRM2	A8BBS6	GMP_PDE_delta domain-containing protein.	ARL1; Belongs to the small GTPase superfamily. Arf family.	0.999
GL50803_27147	GL50803_15906	A8BRM2	A8BEZ7	GMP_PDE_delta domain-containing protein.	Tubulin specific chaperone D.	0.641
GL50803_27147	GL50803_4192	A8BRM2	A8BQH7	GMP_PDE_delta domain-containing protein.	ARL2.	0.824
GL50803_27147	GL50803_7655	A8BRM2	A8BWX1	GMP_PDE_delta domain-containing protein.	C-CAP/cofactor C-like domain-containing protein.	0.641